Journals / Türk Nefroloji Diyaliz ve Transplantasyon Dergisi / 2012 / Cilt: 21 - Sayı: 3

Chronic lithium use as a rare cause of chronic renal failure

Kronik böbrek yetmezliğinin nadir bir nedeni: Kronik lityum kullanımı

Pages
313–315
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We present this case as it is a rare event.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Lithium is the treatment of choice in bipolar disorders.
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Key Findings & Data:A 37-year-old female patient on lithium with proteinuria and renal failure was diagnosed as having chronic tubulointerstistial nephritis and secondary focal segmental glomerulosclerosis at renal biopsy.
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Conclusion & Impact:We present this case as it is a rare event.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Lithium is the treatment of choice in bipolar disorders. Long-term use has important side effects such as nephrotoxicity. A 37-year-old female patient on lithium with proteinuria and renal failure was diagnosed as having chronic tubulointerstistial nephritis and secondary focal segmental glomerulosclerosis at renal biopsy. These fi ndings were linked to lithium use. We present this case as it is a rare event.

Özet

Lityum, bipolar bozuklukların tedavisinde kullanılan en etkin ilaçtır. Uzun süreli kullanımda önemli yan etkileri vardır ve nefrotoksisite bunlardan birisidir. Otuz yedi yaşındaki bayan hasta, proteinüri ve böbrek yetmezliği nedeniyle tetkik edildi ve böbrek biyopsisinde kronik tübülointerstisyel nefrit ve sekonder fokal segmental glomerülokleroz saptandı. Bulgular lityum kullanımına bağlandı. Biz bu olguyu literatürde nadir olması nedeniyle sunuyoruz.

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Cite This Article

GÜNGÖR, Ö., TAMER, A. F., AŞÇI, G., AKÇİÇEK, F., TATAR, E., ŞEN, S. (2022). Chronic lithium use as a rare cause of chronic renal failure. Türk Nefroloji Diyaliz ve Transplantasyon Dergisi, Cilt: 21 - Sayı: 3, 313–315. https://ajindex.com/articles/636417

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References (1)

  1. D’Agati VD, Kaskel FJ, Falk RJ: Focal segmental glomerulosclerosis. N Engl J Med 2011; 365: 2398-2411 2. Hajek T, Alda M, Grof P: Discontinuation of lithium because of side effects. J Psychiatry Neurosci 2011; 36: 39-40 3. Grünfeld JP, Rossier BC: Lithium nephrotoxicity revisited. Nat Rev Nephrol 2009; 5: 270-276 4. McKnight RF, Adida M, Budge K, Stockton S, Goodwin GM, Geddes JR: Lithium toxicity profi le: A systematic review and metaanalysis. Lancet 2012; 379 (9817): 721-728 5. Lazarus JH: Lithium and thyroid. Best Pract Res Clin Endocrinol Metab 2009; 23: 723-733 6. Järhult J, Ander S, Asking B, Jansson S, Meehan A, Kristoffersson A, Nordenström J: Long-term results of surgery for lithiumassociated hyperparathyroidism. Br J Surg 2010; 97: 1680-1685 7. Trepiccione F, Christensen BM: Lithium-induced nephrogenic diabetes insipidus: New clinical and experimental fi ndings. J Nephrol 2010; 16: 43-48 8. Presne C, Fakhouri F, Noël LH, Stengel B, Even C, Kreis H, Mignon F, Grünfeld JP: Lithium-induced nephropathy: Rate of progression and prognostic factors. Kidney Int 2003; 64: 585-592 9. Petersen CE, Amaral S, Frosch E: Lithium-induced nephrotic syndrome in a prepubertal boy. J Child Adolesc Psychopharmacol 2008; 18: 210-213 10. Tam VK, Green J, Schwieger J, Cohen AH: Nephrotic syndrome and renal insuffi ciency associated with lithium therapy. Am J Kidney Dis 1996; 27: 715-720 11. Schreiner A, Waldherr R, Rohmeiss P, Hewer W: Focal segmental glomerulosclerosis and lithium treatment. Am J Psychiatry 2000; 157: 834 12. Santella RN, Rimmer JM, MacPherson BR: Focal segmental glomerulosclerosis in patients receiving lithium carbonate. Am J Med 1988; 84: 951-954 13. Bendz H, Schön S, Attman PO, Aurell M: Renal failure occurs in chronic lithium treatment but is uncommon. Kidney Int 2010; 77: 219-224 14. Lepkifker E, Sverdlik A, Iancu I, Ziv R, Segev S, Kotler M: Renal insuffi ciency in long-term lithium treatment. J Clin Psychiatry 2004; 65: 850-856 15. Presne C, Fakhouri F, Kenouch S, Stengel B, Kreis H, Grünfeld JP: Progressive renal failure caused by lithium nephropathy. Presse Med 2002; 31: 828-833