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Journals / Türk Nefroloji Diyaliz ve Transplantasyon Dergisi / 2012 / Cilt: 21 - Sayı: 1

Should hemodialysis for renal replacement treatment in hospitalized patients with acute kidney ınjury be ıntermittent or continuous

Hastanede yatan hastalarda akut böbrek hasarı tedavisinde aralıklı hemodiyaliz mi, sürekli hemodiyaliz mi?

Ayşegül ORUÇ
Cuma Bülent GÜL
Ayşe HOYRAZLI
Tümay ALTINAY
Nimet AKTAŞ
Abdülmecid YILDIZ
Mustafa GÜLLÜLÜ
Alparslan ERSOY
Pages
72–77
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Mortality rate (52,6%, 88,2%), oligoanuria (63.2%, 94.1%), positive inotrope therapy (28.9%, 85.3%), sepsis (15.8%, 55.9%), mechanical ventilation (15.8%, 76.5%), rate of surgery (2.6%, 32.4%) and the SOFA score (7.1, 9.5) were significantly higher in CHD group.CONCLUSION: The mortality rate was higher in CHD group, and this might be associated with the greater severity of problems such as hemodynamic instability, multi-organ dysfunction and co-morbid diseases in this group.

📌 3 Key Takeaways

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Objective & Hypothesis:OBJECTIVE: Acute kidney injury (AKI) is a frequent complication of hospitalized patients that is associated with high mortality rate despite all developments.
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Key Findings & Data:In our study we aimed to compare the mortality rates of continuous hemodialysis (CHD) and intermittent hemodialysis (IHD) in hospitalized patients.MATERIAL and METHODS: Seventy-two patients in Uludag University Hospital diagnosed with AKI in 2008 were enrolled our study.
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Conclusion & Impact:Mortality rate (52,6%, 88,2%), oligoanuria (63.2%, 94.1%), positive inotrope therapy (28.9%, 85.3%), sepsis (15.8%, 55.9%), mechanical ventilation (15.8%, 76.5%), rate of surgery (2.6%, 32.4%) and the SOFA score (7.1, 9.5) were significantly higher in CHD group.CONCLUSION: The mortality rate was higher in CHD group, and this might be associated with the greater severity of problems such as hemodynamic instability, multi-organ dysfunction and co-morbid diseases in this group.
🔬Design:Research Article
📍Scope:2008 Verileri
⚙️Variables:Domain Parameters

Abstract

OBJECTIVE: Acute kidney injury (AKI) is a frequent complication of hospitalized patients that is associated with high mortality rate despite all developments. Continuous and intermittent hemodialysis are renal replacement treatment modalities for AKI. In our study we aimed to compare the mortality rates of continuous hemodialysis (CHD) and intermittent hemodialysis (IHD) in hospitalized patients.MATERIAL and METHODS: Seventy-two patients in Uludag University Hospital diagnosed with AKI in 2008 were enrolled our study. Intermittent or continuous hemodialysis was prescribed by the nephrology counsultant. Data were recorded from patients files retrospectively.RESULTS: Patients were divided into two groups (38 IHD, 34 CHD). Mortality rate (52,6%, 88,2%), oligoanuria (63.2%, 94.1%), positive inotrope therapy (28.9%, 85.3%), sepsis (15.8%, 55.9%), mechanical ventilation (15.8%, 76.5%), rate of surgery (2.6%, 32.4%) and the SOFA score (7.1, 9.5) were significantly higher in CHD group.CONCLUSION: The mortality rate was higher in CHD group, and this might be associated with the greater severity of problems such as hemodynamic instability, multi-organ dysfunction and co-morbid diseases in this group.

Özet

AMAÇ: Akut böbrek hasarı (ABH) hastanede yatan hastalarda tüm gelişmelere karşın sıklıkla görülebilen ölüm riski yüksek bir komplikasyondur. Aralıklı ve sürekli hemodiyaliz (HD) ABH için böbrek yerine koyma tedavisi yöntemlerindendir. Çalışmamızda, hastanede yatan hastalarda sürekli HD (SHD) ve aralıklı HD (AHD) yöntemlerini ölüm oranları açısından karşılaştırmayı amaçladık.GEREÇ ve YÖNTEMLER: Uludağ Üniversitesi Tıp Fakültesi Hastanesinde 2008 yılı içinde ABH tanısı konularak HD uygulanan 72 hasta çalışmaya alındı. Nefroloji konsültasyonu ile böbrek yerine koyma tedavisi gerektiren hastalara AHD ya da SHD uygulandı. Hasta verileri geriye dönük olarak dosyalarından kaydedildi.BULGULAR: Hastalar hemodiyaliz yöntemlerine göre iki gruba ayrıldı (38 AHD, 34 SHD). Ölüm oranı (%52,6, %88,2), oligoanüri (%63,2, %94,1), inotrop gereksinimi (%28,9, %85,3), sepsis (%15,8, %55,9), mekanik solutma (%15,8, %76,5), operasyon öyküsü (%2,6, %32,4) ve SOFA skoru (7,1, 9,5) SHD grubunda anlamlı olarak yüksek bulundu.SONUÇ: SHD uygulanan grupta ölüm oranını yüksek bulduk. Hemodinamik dengesizlik, çoklu organ yetmezliği ve ek hastalıkların varlığı nedeni ile prognozu kötü hastalarda SHD'in tercih edilmesi yüksek ölüm oranı ile ilişkili olabilir.

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Cite This Article

ORUÇ, A., GÜL, C. B., HOYRAZLI, A., ALTINAY, T., AKTAŞ, N., YILDIZ, A., GÜLLÜLÜ, M., ERSOY, A. (2022). Should hemodialysis for renal replacement treatment in hospitalized patients with acute kidney ınjury be ıntermittent or continuous. Türk Nefroloji Diyaliz ve Transplantasyon Dergisi, Cilt: 21 - Sayı: 1, 72–77. https://ajindex.com/articles/636390

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