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Journals / Türk Nefroloji Diyaliz ve Transplantasyon Dergisi / 2013 / Cilt: 22 - Sayı: 2

Diyaliz hastalarında QTc dispersiyonun sıklığının ve klinik ve laboratuvar parametrelerle ilişkisinin değerlendirilmesi

Evaluation of the frequency of QTc dispersion and ıts relationship with clinical and laboratory parameters in dialysis patients

Ali Kemal KADİROĞLU
Emre AYDIN
Yaşar YILDIRIM
Mehmet Emin YILMAZ
Hasan KAYABAŞI
Zülfikar YILMAZ
Fatma AYDIN YILMAZ
Pages
196–201
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Patients with QTcd >50 ms had significantly higher SBP, urea and ferritin levels, but significantly lower iron binding capacity and calcium levels compared those with QTcd ≤ 50 ms(p

📌 3 Key Takeaways

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Objective & Hypothesis:OBJECTIVE: QTc dispersion is defined as the difference between the maximal and minimal correct QT interval on standard 12-lead ECG.
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Key Findings & Data:Increased QTc dispersion has been reported in ESRD patients.
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Conclusion & Impact:Patients with QTcd >50 ms had significantly higher SBP, urea and ferritin levels, but significantly lower iron binding capacity and calcium levels compared those with QTcd ≤ 50 ms(p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

OBJECTIVE: QTc dispersion is defined as the difference between the maximal and minimal correct QT interval on standard 12-lead ECG. Increased QTc dispersion has been reported in ESRD patients. In our study, we aimed to evaluate the frequency of QTc dispersion and its relationship between clinical and laboratory parameters in patients on regular dialysis programme. MATERIAL and METHODS: Sixty patients underwent dialysis (30 HD, 30 CAPD) and another 30 healthy subjects were enrolled into the study. The standard 12 lead ECGs were performed and QTcd was measured from all dialysis patients and control subjects. Blood samples were collected for the measurement of laboratory parameters. RESULTS: Dialysis patients showed significantly higher QTcd than control subjects (55.75±36.48 versus 28.73±28.27; p=0.001). Patients with QTcd >50 ms had significantly higher SBP, urea and ferritin levels, but significantly lower iron binding capacity and calcium levels compared those with QTcd ≤ 50 ms(p

Özet

AMAÇ: 12 derivasyonlu standart EKG’de en uzun QTc mesafesi ile en kısa QTc mesafesi arasındaki fark QTc dispersiyonu olarak tanımlanır. SDBY hastalarında artmış QTc dispersiyonu bildirilmiştir. Biz çalışmamızda, diyaliz hastalarında QTc dispersiyonunun sıklığını ve klinik ve laboratuvar parametrelerle ilişkisinin değerlendirilmesini amaçladık. GEREÇ ve YÖNTEMLER: Çalışmaya 60 diyaliz hastası (30 HD, 30 PD) ve 30 sağlıklı birey dahil edildi. Tüm diyaliz hastalarının ve katılımcıların 12 derivasyonlu elektrokardiyografileri çekildi ve QTcd ölçüldü. Laboratuvar parametreleri için kan örnekleri toplandı. BULGULAR: Diyaliz hastaları kontrol grubundan daha yüksek QTcd’ye sahipti (55,75±36,48 ve 28,73±28,27; p=0.001). QTcd >50 ms olan hastalar QTcd ≤ 50 ms olanlarla karşılaştırıldığında, SKB, üre ve ferritin anlamlı olarak daha yüksek, Ca ve demir bağlama kapasitesi anlamlı olarak daha düşüktü (p

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Cite This Article

KADİROĞLU, A. K., AYDIN, E., YILDIRIM, Y., YILMAZ, M. E., KAYABAŞI, H., YILMAZ, Z., YILMAZ, F. A. (2022). Diyaliz hastalarında QTc dispersiyonun sıklığının ve klinik ve laboratuvar parametrelerle ilişkisinin değerlendirilmesi. Türk Nefroloji Diyaliz ve Transplantasyon Dergisi, Cilt: 22 - Sayı: 2, 196–201. https://ajindex.com/articles/636312

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References (1)

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