Journals / Türk Nefroloji Diyaliz ve Transplantasyon Dergisi / 2014 / Cilt: 23 - Sayı: 2

Anti-Nükleer Antikor Negatif Lupus ile Birlikte Görülen Full-House Nefropati Olgusu

A Case of Full-House Nephropathy with Anti-Nuclear Antibody Negative Lupus

Pages
161–163
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The patient had signs of lupus such as oral aphthae, symmetrical polyarthritis, and diffuse proliferative glomerulonephritis.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the development of antibodies against a variety of nuclear and cytoplasmic antigens.
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Key Findings & Data:ANA is negative in approximately 5% of patients diagnosed with SLE.
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Conclusion & Impact:The patient had signs of lupus such as oral aphthae, symmetrical polyarthritis, and diffuse proliferative glomerulonephritis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the development of antibodies against a variety of nuclear and cytoplasmic antigens. SLE renal involvement is referred to as lupus nephritis and is generally associated with anti-nuclear antibody (ANA) positivity. ANA is negative in approximately 5% of patients diagnosed with SLE. Existence of full-house nephropathy is generally associated with lupus nephritis. Herein, we present a case of full-house nephropathy in a 48-year-old male patient with negative serology for SLE. The patient had signs of lupus such as oral aphthae, symmetrical polyarthritis, and diffuse proliferative glomerulonephritis.

Özet

Sistemik lupus eritematozus (SLE), çeşitli nükleer ve sitoplazmik antijenlere karşı antikor gelişimi ile karakterize otoimmün bir hastalıktır. SLE renal tutulumu lupus nefriti olarak adlandırılır ve genellikle anti-nükleer antikor (ANA) pozitifliği ile ilişkilidir. SLE tanısı konmuş hastaların yaklaşık %5inde ANA negatiftir. Renal biyopside full-house nefropati varlığı genellikle lupus nefriti ile ilişkilidir. Bu yazıda, full-house nefropatisi olan ve SLE serolojisi negatif olmakla birlikte oral aft, simetrik poliartrit ve diffüz proliferatif glomerülonefrit gibi lupus belirtileri olan 48 yaşındaki bir erkek olgu sunulmuştur.

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Cite This Article

ELÇİOĞLU, Ö. C., ODABAŞ, A. R., ÖZKÖK, A., KILIÇARSLAN, I., BAKAN, A., KANBAY, M., ÖZLÜK, Y., TUNCAN, Ş. (2022). Anti-Nükleer Antikor Negatif Lupus ile Birlikte Görülen Full-House Nefropati Olgusu. Türk Nefroloji Diyaliz ve Transplantasyon Dergisi, Cilt: 23 - Sayı: 2, 161–163. https://ajindex.com/articles/636258

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