Journals / Türk Nefroloji Diyaliz ve Transplantasyon Dergisi / 2015 / Cilt: 24 - Sayı: 2

Periton Diyalizi İlişkili Peritonitlerde Nötrofil-Lenfosit ve Platelet-Lenfosit Oranları

Neutrophil to Lymphocyte and Platelet to Lymphocyte Ratios in Peritoneal Dialysis-Related Peritonitis Periton Diyalizi İlişkili Peritonitlerde Nötrofil-Lenfosit ve

Pages
158–161
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

NLR and PLR are also more simple to calculate and cheaper parameters than classical markers.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Abstract OBJECTIVE: Peritonitis is an important problem for peritoneal dialysis (PD) patients.
📊
Key Findings & Data:It has been demonstrated that the erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) increase nonspecifically in end-stage renal disease (ESRD) without infection.
💡
Conclusion & Impact:NLR and PLR are also more simple to calculate and cheaper parameters than classical markers.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Abstract OBJECTIVE: Peritonitis is an important problem for peritoneal dialysis (PD) patients. It has been demonstrated that the erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) increase nonspecifically in end-stage renal disease (ESRD) without infection. The neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) have been recently investigated as a new alternative inflammatory parameter to distinguish infections and other inflammatory events in a number of studies. We aimed to investigate the diagnostic value of NLR and PLR in bacterial PD peritonitis. MATERIAL and METHODS: In this study, we evaluated 40 peritonitis episodes that we treated. NLR and PLR were calculated from the same blood sample at the beginning and after the treatment of peritonitis. The same parameters were evaluated for 20 control subjects. RESULTS: Classical inflammatory markers such as CRP and ESR; NLR and PLR decreased with the successful treatment of peritonitis, and levels of these parameters were significantly different between the periods (p< 0.05). CONCLUSION: Both NLR and PLR are valuable markers to follow the course of peritonitis and response to the treatment of peritonitis in correlation with conventional inflammation markers of infection. NLR and PLR are also more simple to calculate and cheaper parameters than classical markers.

Özet

Öz AMAÇ: Periton diyalizi (PD) hastaları için peritonit önemli bir sorundur. Son dönem böbrek hastalığı (SDBH) olgularında enfeksiyon olmaksızın, eritrosit sedimantasyon hızı (ESH) ve C- reaktif protein (CRP) düzeylerinin arttığı gösterilmiştir. Nötrofil-lenfosit (NLO) ve platelet-lenfosit oranları (PLO) güncel çalışmalarda enfeksiyöz ve öteki inflamatuvar olayların ayırımında yeni inflamatuvar belirteçler olarak çalışılmıştır. Bakteriyel PD peritonitlerinde NLO ve PLOlarının tanısal değeri araştırıldı. GEREÇ ve YÖNTEMLER: Tedavi ettiğimiz 40 peritonit epizodunu değerlendirdik. NLO ve PLO başlangıçta ve peritonit tedavisi sonrası değerlendirildi. Aynı parametreler 20 kontrol olgusu için de hesaplandı. BULGULAR: CRP ve ESH gibi klasik inflamasyon belirteçleri, NLO ve PLO peritonitin başarılı tedavisi sonrası anlamlı biçimde azaldı (p< 0,05). SONUÇ: NLO ve PLO peritonit seyrinin takibinde değerli parametreler olup, peritonit tedavisi ile klasik inflamasyon belirteçleriyle korelasyon gösteren seyir izlemektedirler. Dahası NLO ve PLO, klasik belirteçlere kıyasla hem daha ucuz ve hem de hesaplanması kolay parametrelerdir. Anahtar sözcükler: Periton diyalizi, Peritonit, Nötrofil-lenfosit oranı, Platelet-lenfosit oranı

🔖

Cite This Article

GÜREL, A., DOĞUKAN, A., ULU, R., ÇELİKER, H., AYGEN, B., YİĞİT, İ. P. (2022). Periton Diyalizi İlişkili Peritonitlerde Nötrofil-Lenfosit ve Platelet-Lenfosit Oranları. Türk Nefroloji Diyaliz ve Transplantasyon Dergisi, Cilt: 24 - Sayı: 2, 158–161. https://ajindex.com/articles/636251

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (13)

  1. Sipahioglu MH, Aybal A, Unal A, Tokgoz B, Oymak O, Utas C: Patient and technique survival and factors affecting mortality on peritoneal dialysis in Turkey: 12 years’ experience in a single center. Perit Dial Int 2008
  2. 28(3):238-245 11. Çelik A, Çamsarı T: CAPD peritonitis and its treatment. Turk Neph Dial Transpl 1994
  3. 4 12. An X, Mao HP, Wei X, Chen JH, Yang X, Li ZB, Yu XQ, Li ZJ: Elevated neutrophil to lymphocyte ratio predicts overall and cardiovascular mortality in maintenance peritoneal dialysis patients. Int Urol Nephrol 2012
  4. 1528 13. Okyay GU, Inal S, Oneç K, Er RE, Paşaoğlu O, Paşaoğlu H, Derici U, Erten Y: Neutrophil to lymphocyte ratio in evaluation of inflammation in patients with chronic kidney disease. Ren Fail 2013
  5. 35(1):29-36 14. Fine A: Relevance of C-reactive protein levels in peritoneal dialysis patients. Kidney Int 2002
  6. 620 15. Hind CRK, Thomson SP, Winearls CG, Pepys MB: Serum C-reactive protein concentration in the management of infection in patients treated by CAPD. J Clin Pathol 1985
  7. 463 16. Turkmen K, Erdur FM, Ozcicek F, Ozcicek A, Akbas EM, Ozbicer A, Demirtas L, Turk S, Tonbul HZ: Platelet-to-lymphocyte ratio better predicts inflammation than neutrophil-to-lymphocyte ratio in end-stage renal disease patients. Hemodial Int 2013
  8. 396 17. Sen BB, Rifaioglu EN, Ekiz O, Inan MU, Sen T, Sen N: Neutrophil to lymphocyte ratio as a measure of systemic inflammation in psoriasis. Cutan Ocul Toxicol 2014
  9. 33(3):223-227 18. Turak O, Özcan F, Işleyen A, Başar FN, Gül M, Yilmaz S, Sökmen E, Yüzgeçer H, Lafçi G, Topaloğlu S, Aydoğdu S: Usefulness of Neutrophil to lymphocyte ratio to predict ın- hospital outcomes in infective endocarditis. Can J Cardiol 2013
  10. 29(12):1672-1678 19. de Jager CP, Wever PC, Gemen EF, Kusters R, van Gageldonk- Lafeber AB, van der Poll T, Laheij RJ: The neutrophil- lymphocyte count ratio in patients with community- acquired pneumonia. PLoS One 2012
  11. 7(10):e46561 20. Terradas R, Grau S, Blanch J, Riu M, Saballs P, Castells X, Horcajada JP, Knobel H: Eosinophil count and neutrophil- lymphocyte count ratio as prognostic markers in patients with bacteremia: A retrospective cohort study. PLoS One 2012
  12. 7(8):e42860 21. de Jager CP, van Wijk PT, Mathoera RB, de Jongh- Leuvenink J, van der Poll T, Wever PC: Lymphocytopenia and neutrophil- lymphocyte count ratio predict bacteremia better than conventional infection markers in an emergency care unit. Crit Care 2010
  13. 14(5):R192 22. Markar SR, Karthike