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Journals / Türk Nefroloji Diyaliz ve Transplantasyon Dergisi / 2016 / Cilt: 25 - Sayı: 2

Locking of Tunneled Cuffed Hemodialysis Catheters with a Mixture of 45% Ethanol and 4% Trisodium Citrate is Effective in Preventing Catheter-Related Infections and Thrombosis

Tünelli Keçeli Hemodiyaliz Kataterlerinin %45 Etanol ve %4 Trisodyum Sitrattan Oluşan Karışım ile Kapanması Kateter İlişkili Enfeksiyonların ve Trombozun Önlenmesinde Etkindir

Erkan YILMAZ
Bülent TOKGÖZ
Murat Hayri SİPAHİOĞLU
Oktay OYMAK
Aydın ÜNAL
İsmail KOÇYİĞİT
Tamer ARIKAN
Nilüfer OĞUZHAN
Onur TUNCA
Mustafa SOYLAK
Pages
168–174
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It also is as effective as heparin on the prevention of the development of catheter thrombosis.

📌 3 Key Takeaways

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Objective & Hypothesis:OBJECTIVE: In this study, we aimed to investigate the effect of a mixture consisting of 45% ethanol and 4% trisodium citrate (E-TSC) on the development of catheter-related infection (CRI) and catheter thrombosis in hemodialysis patients.
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Key Findings & Data:MATERIAL and METHODS: A total of 114 patients were included in the study.
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Conclusion & Impact:It also is as effective as heparin on the prevention of the development of catheter thrombosis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

OBJECTIVE: In this study, we aimed to investigate the effect of a mixture consisting of 45% ethanol and 4% trisodium citrate (E-TSC) on the development of catheter-related infection (CRI) and catheter thrombosis in hemodialysis patients. MATERIAL and METHODS: A total of 114 patients were included in the study. Patients were separated into two groups according to the type of catheter lock solution as the E-TSC and classic heparin groups. There were 51 patients in the E-TSC group and 63 patients in the heparin group. RESULTS: The development of CRI was significantly lower in the E-TSC group compared to the heparin group (p= 0.011). CRI developed in only 1 patient in the E-TSC group whereas it developed in 10 patients in the heparin group. There was no significant difference between the two groups with regard to the development of thrombosis (p > 0.05). CONCLUSION: E-TSC solution has favorable effects on the prevention of the development of CRI compared to classic heparin. It also is as effective as heparin on the prevention of the development of catheter thrombosis.

Özet

AMAÇ: Çalışmada, hemodiyaliz hastalarında kateter ilişkili enfeksiyon (KİE) ve kateter trombozu gelişimi üzerine %45 etanol ve %4 trisodyum sitrattan (E-TSS) oluşan karışımının etkisini araştırmayı amaçladık. GEREÇ ve YÖNTEMLER: Çalışmaya toplam 114 hasta dahil edildi. Hastalar kateter kapama solüsyonun tipine göre iki gruba ayrıldı: E-TSS ve klasik heparin grupları. E-TSS grubunda 51 hasta, heparin grubunda 63 hasta mevcuttu. BULGULAR: KİE gelişimi E-TSS grubunda heparin grubuna kıyasla anlamlı olarak daha düşüktü (p= 0,011). E-TSS grubunda sadece bir hastada KİE gelişirken heparin grubunda 10 hastada KİE gelişti. Tromboz gelişimi açısından 2 grup arasında anlamlı fark yoktu (p > 0,05). SONUÇ: E-TSS solüsyonu, klasik heparine kıyasla, KİE gelişiminin önlenmesi üzerine olumlu etkilere sahiptir. Bu solüsyon ayrıca kateter trombozu gelişimini önlemede heparin kadar etkindir.

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Cite This Article

YILMAZ, E., TOKGÖZ, B., SİPAHİOĞLU, M. H., OYMAK, O., ÜNAL, A., KOÇYİĞİT, İ., ARIKAN, T., OĞUZHAN, N., TUNCA, O., SOYLAK, M. (2022). Locking of Tunneled Cuffed Hemodialysis Catheters with a Mixture of 45% Ethanol and 4% Trisodium Citrate is Effective in Preventing Catheter-Related Infections and Thrombosis. Türk Nefroloji Diyaliz ve Transplantasyon Dergisi, Cilt: 25 - Sayı: 2, 168–174. https://ajindex.com/articles/636201

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