Journals / Türk Nefroloji Diyaliz ve Transplantasyon Dergisi / 2016 / Cilt: 25 - Sayı: 3

Relation Between Circadian Blood Pressure Variation and Estimated GFR in Normotensives

Normotansif Kişilerde Sirkadyen Kan Basıncı Değişikliklerinin eGFR ile İlişkisi

Pages
279–282
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

When the partial correlation test was performed, the night SBP reduction rate was associated with serum creatinine (r= -0.312, p=0.002) and eGFR (r= 0.319, p=0.002)

📌 3 Key Takeaways

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Objective & Hypothesis:The aim of this study was to evaluate the effects of circadian blood pressure variation on estimated GFR in normotensive patients who have normal serum creatinine levels.
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Key Findings & Data:MATERIAL and METhODS: In this retrospective study, ambulatory blood pressure monitoring of 102 patients was performed with the Suntech AccuWin ProV3.RESULTS: 50 (49%) out of 102 patients were female and 52 (51%) were male with a mean age of 49.8±15.6 years.
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Conclusion & Impact:When the partial correlation test was performed, the night SBP reduction rate was associated with serum creatinine (r= -0.312, p=0.002) and eGFR (r= 0.319, p=0.002)
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The aim of this study was to evaluate the effects of circadian blood pressure variation on estimated GFR in normotensive patients who have normal serum creatinine levels. MATERIAL and METhODS: In this retrospective study, ambulatory blood pressure monitoring of 102 patients was performed with the Suntech AccuWin ProV3.RESULTS: 50 (49%) out of 102 patients were female and 52 (51%) were male with a mean age of 49.8±15.6 years. When patients were divided into dipper and nondipper groups according to night systolic blood pressure (SBP) reduction, Egfr levels were significantly different between the groups. When the partial correlation test was performed, the night SBP reduction rate was associated with serum creatinine (r= -0.312, p=0.002) and eGFR (r= 0.319, p=0.002)

Özet

Normotansif ve serum kreatinin düzeyleri normal olan kişilerde dipper ve nondipper kan basıncı değişiminin tahmini glomerüler filtrasyon hızı (eGFR) üzerine etkisini değerlendirmektir. GEREÇ ve YÖNTEMLER: 102 normotansif kişinin ayaktan kan basıncı izlemi (AKBİ) ve serum kreatinin değerleri retrospektif olarak değerlendirildi. Gece sistolik kan basıncı (SKB) azalma oranları hesaplandı. MDRD eşitliği kullanılarak eGFR düzeyleri hesaplandı. BULGULAR: Olgular dipper (51 kişi, kadın/erkek:25/26) ve nondipper (51 kişi, kadın/erkek:25/26) gruplarına ayrıldı. Nondipper grubun eGFR düzeyleri anlamlı olarak daha düşük bulundu (76,1±15,5 vs 88,6±24,3, p=0,003). Parsiyel korelasyon analizinde, gece kan basıncı azalma oranı ile eGFR (r= 0,319, p=0,002) ve kreatinin (r=-0,312, p=0,002) arasında anlamlı korelasyon saptandı. Gece SKB azalma oranı ile eGFR arasında bağımsız ilişki olduğu görüldü (ß:0,096 p:0,002).SONUÇ: Normotansif kişilerde bozulmuş sirkadyen kan basıncı değişikliği, subklinik böbrek hasarı ile birliktelik gösterebilir

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Cite This Article

ÖZTÜRK, M. T., EBİNÇ, F. A., KUTLUGÜN, A. A., EFE, F. K. (2022). Relation Between Circadian Blood Pressure Variation and Estimated GFR in Normotensives. Türk Nefroloji Diyaliz ve Transplantasyon Dergisi, Cilt: 25 - Sayı: 3, 279–282. https://ajindex.com/articles/636192

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