Journals / Türk Nefroloji Diyaliz ve Transplantasyon Dergisi / 2016 / Cilt: 25 - Sayı: 1

Metformine Bağlı Nefrotik Sendrom

Nephrotic Syndrome Due to Metformin

Pages
118–120
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Our case is important as it is the first case with nephrotic syndrome due to metformin in the literature

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Heavy proteinuria and nephrotic syndrome may occur in association with a wide variety of primary and systemic diseases and also with drugs.
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Key Findings & Data:Major drugs that can induce nephrotic syndrome and glomerular damage are gold, penicillamine, bucillamine and non-steroidal anti-inflammatory drugs.
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Conclusion & Impact:Our case is important as it is the first case with nephrotic syndrome due to metformin in the literature
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Heavy proteinuria and nephrotic syndrome may occur in association with a wide variety of primary and systemic diseases and also with drugs. Major drugs that can induce nephrotic syndrome and glomerular damage are gold, penicillamine, bucillamine and non-steroidal anti-inflammatory drugs. In nephrotic syndrome due to these drugs, the major type of renal disease is membranous glomerulonephritis and the nephropathy resolves completely when the drug is withdrawn. Here we report a patient who developed nephrotic syndrome after the initiation of metformin. Laboratory parameters improved rapidly after the discontinuation of the drug. Our case is important as it is the first case with nephrotic syndrome due to metformin in the literature

Özet

Ağır proteinüri ve nefrotik sendrom primer, sekonder hastalıklar ya da ilaçların değişik oranlarda katkıları ile birlikte oluşabilir. Altın, penisilamin, busilamin ve steroid olmayan yangı giderici ilaçlar nefrotik sendrom ve glomerüler hasarı oluşturan önemli ilaçlardır. Bu ilaçlardan dolayı oluşan nefrotik sendromda renal hastalığın önemli tipi membranöz glomerülonefrittir ve ilaç kesildiği zaman nefropati tamamı ile gerileyebilir. Biz metformin başlandıktan sonra nefrotik sendrom gelişen olguyu rapor ediyoruz. Laboratuvar parametreleri ilaç kesildikten sonra hızlı birşekilde iyileşmişti. Bizim olgumuz literatürde metformine bağlı nefrotik sendrom olan ilk olgu olmasından dolayı öneme sahiptir

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Cite This Article

KARAKAŞ, Y., TAŞTEKİN, F., ŞAHİN, G., AÇIKALIN, M. F. (2022). Metformine Bağlı Nefrotik Sendrom. Türk Nefroloji Diyaliz ve Transplantasyon Dergisi, Cilt: 25 - Sayı: 1, 118–120. https://ajindex.com/articles/636186

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