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Journals / Türk Nefroloji Diyaliz ve Transplantasyon Dergisi / 2016 / Cilt: 25 - Sayı: 3

Crescentic Henoch-Schonlein Purpura Nephritis and p-ANCA Positivity in a Case with Advanced Age

İleri Yaştaki Bir Olguda Kresentik Henoch-Schönlein Purpurası Nefriti ve p-AncA Pozitifliği

Caner ÇAVDAR
Ali ÇELİK
Serkan YILDIZ
Taner ÇAMSARI
Sülen SARIOĞLU
Evrim BOZKAYA
Mehtat ÜNLÜ
Aykut SİFİL
Pages
324–328
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We report here a case of crescentic HSP nephritis with perinuclear anti-neutrophil cytoplasmic antibody (p-ANCA) positivity

📌 3 Key Takeaways

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Objective & Hypothesis:Henoch-Schönlein purpura (HSP) is a vasculitis characterized by purpuric rash, arthritis, nephritis and gastrointestinal symptoms and it is generally seen in children.
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Key Findings & Data:Henoch-Schönlein purpura (HSP) is a vasculitis characterized by purpuric rash, arthritis, nephritis and gastrointestinal symptoms and it is generally seen in children.
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Conclusion & Impact:We report here a case of crescentic HSP nephritis with perinuclear anti-neutrophil cytoplasmic antibody (p-ANCA) positivity
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Henoch-Schönlein purpura (HSP) is a vasculitis characterized by purpuric rash, arthritis, nephritis and gastrointestinal symptoms and it is generally seen in children. We report here a case of crescentic HSP nephritis with perinuclear anti-neutrophil cytoplasmic antibody (p-ANCA) positivity

Özet

Henoch-Schönlein purpurası (HSP) sıklıkla çocuklarda görülen, purpurik döküntü, artrit, nefrit ve gastrointestinal semptomlar ile karakterize sistemik küçük damar vaskülitidir. Yazıda perinükleer anti-nötrofil sitoplazmik antikor (p-ANCA) pozitifliği saptanan ileri yaş kresentik HSP nefriti olgusu sunulmuştur.Olgu 78 yaşında ve erkek idi. İdrarda azalma, nefes darlığı, karın ağrısı, eklem ağrısı ve ödem yakınmaları ile hastanemize başvurdu. Fizik bakıda gluteal bölgede ve her iki alt ekstremitede purpura tarzında döküntüler vardı. Böbrek yetmezliği, proteinüri ve hematüri saptandı. Nefroloji kliniğine yatırıldı ve hemodiyaliz tedavisine başlandı. Cilt biyopsisinde damar duvarlarında granüler IgA depolanması ve böbrek biyopsisinde kresentik IgA saptandı. Kresentik HSP nefriti düşünüldü. Serum kompleman düzeyleri normal sınırlarda ölçülen olguda p-ANCA pozitifliği saptandı. Plazmaferez tedavisi ile birlikte damardan yüksek doz metilprednizolon ve siklofosfamid tedavisi uygulandı

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Cite This Article

ÇAVDAR, C., ÇELİK, A., YILDIZ, S., ÇAMSARI, T., SARIOĞLU, S., BOZKAYA, E., ÜNLÜ, M., SİFİL, A. (2022). Crescentic Henoch-Schonlein Purpura Nephritis and p-ANCA Positivity in a Case with Advanced Age. Türk Nefroloji Diyaliz ve Transplantasyon Dergisi, Cilt: 25 - Sayı: 3, 324–328. https://ajindex.com/articles/636181

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References (11)

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