Journals / Türk Nefroloji Diyaliz ve Transplantasyon Dergisi / 2016 / Cilt: 25 - Sayı: 2

Non-Caseating Granulamatus Nephritis: Rare Sign of Sarcoidosis

Non-Kazeifiye Granülomatöz Nefrit: Sarkoidozun Nadir Bulgusu

Pages
215–217
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Proteinuria and serum creatinine increase are important in patients with sarcoidosis and treatment must be started immediately to prevent end-stage renal failure.

📌 3 Key Takeaways

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Objective & Hypothesis:Sarcoidosis is chronic multisystem granulomatous disease.
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Key Findings & Data:We diagnosed non-caseating granulomatous nephritis with renal biopsy in a 50-year-old female pulmonary sarcoidosis case.
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Conclusion & Impact:Proteinuria and serum creatinine increase are important in patients with sarcoidosis and treatment must be started immediately to prevent end-stage renal failure.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Sarcoidosis is chronic multisystem granulomatous disease. It can rarely cause renal structural and functional damage. Renal impairment is mostly due to the calcium metabolism and associated with hypercalciuria, nephrolithiasis and nephrocalcinosis. Non-caseating granulomatous nephritis can also be seen in few patients. We diagnosed non-caseating granulomatous nephritis with renal biopsy in a 50-year-old female pulmonary sarcoidosis case. Steroid treatment was immediately started and there was a significant decrease in proteinuria and creatinine after a month. Proteinuria and serum creatinine increase are important in patients with sarcoidosis and treatment must be started immediately to prevent end-stage renal failure.

Özet

Sarkoidoz multisistemik ve kronik granülomatöz bir hastalıktır. Sarkoidoz nadir olarak böbrekte yapısal ve fonksiyonel hasara yol açar. Renal tutulum daha çok kalsiyum metabolizmasına bağlı hiperkalsiüri, nefrolityazis, nefrokalsinozise bağlı görülür. Non-kazeifiye granülomatöz nefrit daha az hastada görülebilir. Biz akciğer sarkoidoz tanısı almış 50 yaşında kadın hastada renal biopsi ile nonkazefiye granülomatöz nefrit tespit ettik. Hemen steroid tedavisi başladık, bir ay sonra serum kreatinin ve proteinürinin azaldığını bulduk. Sarkoidoz tanısı alan hastalarda proteinüri ve serum kreatinin artışı önemli olup hemen renal biopsi yapılıp son dönem böbrek yetmezliğine ilerlemeden tedavisi yapılmalıdır.

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Cite This Article

GÜNEY, İ., YAZICI, R., ASLAN, U., GENÇER, V., BÖLÜKBAŞ, Ö., ESEN, H. (2022). Non-Caseating Granulamatus Nephritis: Rare Sign of Sarcoidosis. Türk Nefroloji Diyaliz ve Transplantasyon Dergisi, Cilt: 25 - Sayı: 2, 215–217. https://ajindex.com/articles/636142

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References (1)

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