Journals / Türk Nefroloji Diyaliz ve Transplantasyon Dergisi / 2017 / Cilt: 26 - Sayı: 2

Acute Kidney Injury Related to Intravenous Immunoglobulin Therapy: A Case Report

İntravenöz İmmünglobulin Tedavisi ile İlişkili Akut Böbrek Hasarı: Olgu Sunumu

Pages
232–235
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The patients should be monitored closely after IVIG therapy for renal injury.

📌 3 Key Takeaways

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Objective & Hypothesis:Intravenous immunoglobulin (IVIG) has been developed for the treatment of hypogammaglobulinemia and is also used for many systemic inflammatory and autoimmune disorders.
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Key Findings & Data:We present the case of an 81-year old woman, treated for acute inflammatory demyelinating polyneuropathy (Guillain-Barré syndrome) that caused loss of sensation and muscle weakness in the leg.
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Conclusion & Impact:The patients should be monitored closely after IVIG therapy for renal injury.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Intravenous immunoglobulin (IVIG) has been developed for the treatment of hypogammaglobulinemia and is also used for many systemic inflammatory and autoimmune disorders. Acute kidney injury is a rare complication of the use of IVIG, and is mainly caused by stabilizing agents in the protein formulation. A complete recovery of renal function is seen within days. We present the case of an 81-year old woman, treated for acute inflammatory demyelinating polyneuropathy (Guillain-Barré syndrome) that caused loss of sensation and muscle weakness in the leg. She was treated with IVIG for five days. Renal failure developed during treatment. The patient's acute kidney injury resolved a month later. The patients should be monitored closely after IVIG therapy for renal injury.

Özet

İntravenöz immünglobulin hipogamaglobinemi tedavisinde kullanılmak üzere geliştirilmiş ve sonrasında birçok otoimmün, inflamatuvar sistemik hastalıkta kullanım alanı bulmuştur. Akut böbrek hasarı, intravenöz immünglobulin tedavisinin nadir bir komplikasyonu olup sıklıkla formülasyondaki stabilizatör maddeye bağlı gelişir ve günler içinde böbrek fonksiyonları geri kazanılır. Bu yazıda bir haftadır bacaklarında güçsüzlük ve his kaybı şikayeti ile akut inflamatuvar demyelinizan polinöropati (Guillaine Barre Sendromu) tanısı konulan; beş günlük intravenöz immünglobulin tedavisi sonrası akut böbrek hasarı gelişen ve bir ay sonra böbrek fonksiyonları tam olarak düzelen 81 yaşında kadın bir olgu sunulmuştur. İntravenöz immünglobulin kullanımı sonrası akut böbrek hasarı açısından hastalar mutlaka yakından izlenmelidir.

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Cite This Article

BİLİCİ, M., BORAZAN, A., KARAÇAY, Ş. Ö., YILMAZ, F. (2022). Acute Kidney Injury Related to Intravenous Immunoglobulin Therapy: A Case Report. Türk Nefroloji Diyaliz ve Transplantasyon Dergisi, Cilt: 26 - Sayı: 2, 232–235. https://ajindex.com/articles/636124

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