Journals / Türk Mikrobiyoloji Cemiyeti Dergisi / 2007 / Cilt: 37 - Sayı: 3

Susceptibility of Streptococcus pneumoniae strains to widely used antibiotics in the treatment

Streptococcus pneumoniae suşlarının tedavide sık kullanılan antibiyotiklere karşı duyarlılıkları

Pages
147–151
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

All penicillin resistant isolates and 82.4% of the penicillin intermediate resistant isolates were resistant to at least two antibiotics.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The worldwide increase of resistance to penicillin and other widely used antibiotics prefered in the treatment of S. pneumoniae infections has become a serious problem within the last 20 years.
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Key Findings & Data:Antimicrobial resistance of 78 S. pneumoniae strains, which isolated from clinical samples between June 2004 and May 2005, to penicillin, erythromycin, azithromycin, trimethoprim- sulfamethoxazole, cefotaxime, cefuroxime, doxycycline, ofloxacin and levofloxacin were determined by E test method (AB-Biodisk, Sweeden).
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Conclusion & Impact:All penicillin resistant isolates and 82.4% of the penicillin intermediate resistant isolates were resistant to at least two antibiotics.
🔬Design:Research Article
📍Scope:2004 Verileri
⚙️Variables:Domain Parameters

Abstract

The worldwide increase of resistance to penicillin and other widely used antibiotics prefered in the treatment of S. pneumoniae infections has become a serious problem within the last 20 years. Antimicrobial resistance of 78 S. pneumoniae strains, which isolated from clinical samples between June 2004 and May 2005, to penicillin, erythromycin, azithromycin, trimethoprim- sulfamethoxazole, cefotaxime, cefuroxime, doxycycline, ofloxacin and levofloxacin were determined by E test method (AB-Biodisk, Sweeden). The rates of penicilin resistance and intermediate resistance of strains were 7.7% and 21.8% respectively. The highest resistance rates was detected for trimethoprim-sulfametaxazole (28.2%), azithromycin (16.7%) and erythromycin (14.1%). All penicillin resistant isolates and 82.4% of the penicillin intermediate resistant isolates were resistant to at least two antibiotics.

Özet

Son yirmi yılda, Streptococcus pneumoniae infeksiyonlarının tedavisinde tercih edilen penisilin ve sık kullanılan diğer antimikrobiyallere karşı direncin artması tüm dünyada önemli bir problem haline gelmiştir. Çalışmamızda Haziran 2004 - Mayıs 2005 tarihleri arasında izole edilen 78 adet S. pneumoniae suşunun penisilin, eritromisin, azitromisin, trimetoprim-sulfametoksazol, sefotaksim, sefuroksim, doksisiklin, ofloksasin ve levofloksasine karşı duyarlılıkları E test yöntemiyle (AB-Biodisk, Sweeden) değerlendirilmiştir. Penisiline orta dirençli ve dirençli suşların oranı sırasıyla %21.8 ve %7.7 olarak bulunmuştur. En yüksek direnç oranları trimetoprim-sulfametoksazol (%28.2), azitromisin (%16.7) ve eritromisine (% 14.1) karşı görülmüştür. Penisilin dirençli suşların tamamının ve orta dirençli suşların %82.4'ünün en az iki antibiyotiğe dirençli olduğu tespit edilmiştir.

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Cite This Article

KARAHAN, Z. C., BALABAN, N., SULTAN, N., BODUR, H., HAYIRLIOĞLU, N., MUMCUOĞLU, İ. (2022). Susceptibility of Streptococcus pneumoniae strains to widely used antibiotics in the treatment. Türk Mikrobiyoloji Cemiyeti Dergisi, Cilt: 37 - Sayı: 3, 147–151. https://ajindex.com/articles/636010

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