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Journals / Türk Mikrobiyoloji Cemiyeti Dergisi / 2007 / Cilt: 37 - Sayı: 1

Ventilator associated pneumoniae pathogens isolated from intensive care unit patients by mini-bal cultures and their antibiotic susceptibilities

Yoğun bakım ünitesi hastalarından mini-bal kültürü ile izole edilen ventilatörle ilişkili pnömoni etkenleri ve çeşitli antibiyotiklere duyarlılıkları

Nuran Arslan KARABULUT
Nursu ŞAHİN
Emin BULUT
Banu BAYRAKTAR
Pages
15–18
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

High resistance rates for antibiotics suggested that the treatment of the empirical antibiotics recommended for VAP cases should be updated according to the surveillance data.

📌 3 Key Takeaways

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Objective & Hypothesis:The aim of this prospective study was to determine the ventilator-associated pneumoniae (VAP) pathogens isolated from mini- bronchoalveolar lavage (mini-BAL) samples obtained from patients in intensive care unit (ICU); to distinguish them from colonizing bacteria; to determine the micro-organisms distribution and their susceptibilities to several antibiotics in ICU.
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Key Findings & Data:Totally 41 strains were isolated from 64 mini-BAL samples obtained from 16 patients in ICU between February 2005 and June 2005.
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Conclusion & Impact:High resistance rates for antibiotics suggested that the treatment of the empirical antibiotics recommended for VAP cases should be updated according to the surveillance data.
🔬Design:Research Article
📍Scope:2005 Verileri
⚙️Variables:Domain Parameters

Abstract

The aim of this prospective study was to determine the ventilator-associated pneumoniae (VAP) pathogens isolated from mini- bronchoalveolar lavage (mini-BAL) samples obtained from patients in intensive care unit (ICU); to distinguish them from colonizing bacteria; to determine the micro-organisms distribution and their susceptibilities to several antibiotics in ICU. Totally 41 strains were isolated from 64 mini-BAL samples obtained from 16 patients in ICU between February 2005 and June 2005. Acinetobacter spp and Pseudomonas aeruginosa were the most frequently isolated species from mini-BAL samples. Antimicrobials which show the highest susceptibility rates for P. aeruginosa were as follows: the amicasin (83%) , ceftazidime (67%), ciprofloxasin (67%), cefepime (58%), piperacillin-tazobactam (58%); Acinetobacter strains were highly resistant to all avaliable antimicrobials and netilmicin (73%) susceptibility rate was the highest among them. High resistance rates for antibiotics suggested that the treatment of the empirical antibiotics recommended for VAP cases should be updated according to the surveillance data.

Özet

Bu prospektif çalışmada, yoğun bakım ünitesinde (YBÜ) mini-bronkoalveolar lavaj (mini-BAL) yöntemiyle incelenen örneklerden izole edilen ventilatörle ilişkili pnömoni (VİP) etkenleri ile bu etkenlerin kolonize bakterilerden ayrımı, tür dağılımı ve çeşitli antibiyotiklere duyarlılıklarının belirlenmesi amaçlanmıştır. Şubat 2005-Haziran 2005 tarihleri arasında 16 YBÜ hastasından alınan 64 mini-BAL örneğinden 41 suş izole edilmiştir. Acinetobacter spp. ve Pseudomonas aeruginosa en sık üreyen mikroorganizmalar olmuştur. P. aeruginosa için en etkili antibiyotiklerin amikasin (%83) , seftazidim (%67), siprofloksasin (%67), sefepim (%58) ve piperasilin-tazobaktam (%58) olduğu; Acinetobacter türlerinin çoklu antibiyotik direnci gösterdiği, en etkili olan antibiyotiğin netilmisin (%73) olduğu görülmüştür. Antibiyotiklere karşı görülen yüksek direnç oranları, VİP olgularının ampirik tedavisinin sürekli güncellenmesi gerektiğini düşündürmektedir.

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Cite This Article

KARABULUT, N. A., ŞAHİN, N., BULUT, E., BAYRAKTAR, B. (2022). Ventilator associated pneumoniae pathogens isolated from intensive care unit patients by mini-bal cultures and their antibiotic susceptibilities. Türk Mikrobiyoloji Cemiyeti Dergisi, Cilt: 37 - Sayı: 1, 15–18. https://ajindex.com/articles/635983

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