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Journals / Türk Klinik Biyokimya Dergisi / 2016 / Cilt: 14 - Sayı: 1

Immunoturbidimetric and Electrochemiluminescence Methods for Ferritin Measurement

Ferritin Ölçümü için İmmunoturbidimetrik ve Elektrokemilüminesans Yöntemler

Defne ÖZBEK
Fatma Demet İNCE
Ramazan AVCI
Elif Merve ARI
Merve ZEYTİNLİ
Hamit Yaşar ELLİDAĞ
Pages
51–57
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results: Although a strong positive correlation (r=0.999; p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Purpose: The measurement of serum ferritin is used as a reliable and noninvasive method for the monitoring of iron stores.
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Key Findings & Data:Material and Methods: The 109 blood samples were analyzed by immunoturbidimetric and electrochemiluminescent method.
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Conclusion & Impact:Results: Although a strong positive correlation (r=0.999; p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: The measurement of serum ferritin is used as a reliable and noninvasive method for the monitoring of iron stores. There are many different methods for the ferritin measurement. However, the immunoturbidimetric method that having the less cost and possibility of the simultaneously ferritin measurement with other parameters is more useful than electrochemiluminescent method. Thus, we aimed to compare the results of immunoturbidimetric and electrochemiluminescent method. Material and Methods: The 109 blood samples were analyzed by immunoturbidimetric and electrochemiluminescent method. The comparison study was performed according to the Clinical Laboratory Standards Institute EP9-A3 protocol. The bias between two methods was evaluated according to acceptable systematic error limit. Diagnostic agreement according to the reference value was analyzed by the Kappa test. Results: Although a strong positive correlation (r=0.999; p

Özet

Amaç: Serum ferritin ölçümü, demir depolarının izlenmesi için güvenilir ve non-invaziv bir yöntem olarak kullanılmaktadır. Ferritin ölçümü için birçok farklı yöntem bulunmaktadır. Bununla birlikte, daha az maliyet ile diğer parametrelerin eş zamanlı ölçüm olanağına sahip immunoturbidimetrik yöntem, elektrokemilüminesans yönteme göre daha kullanışlıdır. Bu nedenle,immunoturbidimetrik yöntem ile elektrokemiluminesans yöntem sonuçlarının karşılaştırılmasını amaçladık. Materyal ve Metod: 109 kan örneği immünoturbidimetrik ve elektrokemiluminesans yöntem ile analiz edildi. Karşılaştırma çalışması, Klinik Laboratuar Standartları Enstitüsü EP9-A3 protokolüne uygun olarak gerçekleştirildi. İki yöntem arasındaki bias kabul edilebilir sistematik hata sınırına göre değerlendirildi. Referans değerlere göre tanısal uyum Kappa testi ile analiz edildi. Bulgular: İmmünoturbidimetrik ve elektrokemiluminesans yöntem sonuçları arasında güçlü pozitif korelasyon (r=0.999; p

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Cite This Article

ÖZBEK, D., İNCE, F. D., AVCI, R., ARI, E. M., ZEYTİNLİ, M., ELLİDAĞ, H. Y. (2022). Immunoturbidimetric and Electrochemiluminescence Methods for Ferritin Measurement. Türk Klinik Biyokimya Dergisi, Cilt: 14 - Sayı: 1, 51–57. https://ajindex.com/articles/634411

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