Journals / Türk Kardiyoloji Derneği Arşivi / 2000 / Cilt: 28 - Sayı: 4

Severe mechanic hemolysis after complete coil occlusion of patent ductus arterious due to streptokinase treatment

Duktus arteriozus açıklığının transkateter yolla tam oklüzyonundan sonra streptokinaza bağlı gelişen mekanik hemoliz

Pages
262–265
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This experience shows that if anticoagulant / fibrinolytic therapy is necessary in completely occluded patent ductus arteriosus patients, preparedness for recanalization of the arterial duct and related complications is mandatory.

📌 3 Key Takeaways

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Objective & Hypothesis:Streptokinase was used for femoral artery thrombosis in a child after the implantation of a Jackson coil for her moderate sized patent ductus arteriosus.
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Key Findings & Data:Left-to-right shunt did not stop even 35 hours after the cessation of streptokinase and severe anemia developed due to mechanical hemolysis.
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Conclusion & Impact:This experience shows that if anticoagulant / fibrinolytic therapy is necessary in completely occluded patent ductus arteriosus patients, preparedness for recanalization of the arterial duct and related complications is mandatory.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Streptokinase was used for femoral artery thrombosis in a child after the implantation of a Jackson coil for her moderate sized patent ductus arteriosus. Severe hemoglobinuria developed after the observation of patency in femoral artery although complete occlusion of the patent ductus arteriosus had been achieved angiographically. Left-to-right shunt did not stop even 35 hours after the cessation of streptokinase and severe anemia developed due to mechanical hemolysis. In order to get rid of this complication, a second Jackson coil was implanted in another procedure. This experience shows that if anticoagulant / fibrinolytic therapy is necessary in completely occluded patent ductus arteriosus patients, preparedness for recanalization of the arterial duct and related complications is mandatory.

Özet

Duktus arteriozus açıklığı nedeni ile transkateter yolla "Jackson coil" uygulanarak tam oklüzyon sağlanan bir hastada izlem sırasında femoral arter trombozu gelişti. Tromboza yönelik streptokinaz perfüzyonuna bağlandı. Ancak femoral komplikasyonun düzelmesi ile birlikte hastada hemoglobinüri gözlendi. Fibrinolitik tedavinin kesilmesinden bir gün sonra duktal şantı devam eden ve mekanik hemoliz nedeniyle derin anemiye giren hastaya ikinci "coil" uygulanmak zorunda kalındı. Bu deneyim, antikoagülan/fibrinolitik tedavi gerektiren tam oklüzyon sağlanmış duktus arteriozus açıklığı olgularında rekanalizasyon gelişebileceğini ve buna bağlı komplikasyonlara karşı hazırlıklı olunması gerekliliğini vurgulamaktadır.

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Cite This Article

AYDOĞAN, Ü., CANTEZ, T., TORUN, E., GEMİCİ, H., ERTUĞRUL, T. (2022). Severe mechanic hemolysis after complete coil occlusion of patent ductus arterious due to streptokinase treatment. Türk Kardiyoloji Derneği Arşivi, Cilt: 28 - Sayı: 4, 262–265. https://ajindex.com/articles/634085

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