Journals / Türk Kardiyoloji Derneği Arşivi / 2001 / Cilt: 29 - Sayı: 1

Effect of left bundle-branch block on systolic and diastolic left ventricular functions with and without heart failure

Kalp yetersizliğinde sol ventrikülün sistolik ve diyastolik fonksiyonuna sol dal blokunun etkisi

Pages
40–46
Publication Date
2022-11-04
DOI
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Comparison with group I and group II patients showed that there was a similarity between LV systolic function parameters while the diastolic function parameters were statistically different (E/A, p=0.004; EAR, p

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Objective & Hypothesis:We designed this study to examine the effect of left bundle-branch block (LBBB) on systolic and diastolic functions of the left ventricle (LV) in patients with heart failure and in subjects with isolated LBBB.
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Key Findings & Data:Methods: A comparison between 36 patients with heart failure and LBBB (group I), 36 patients with heart failure without LBBB (group II) and 41 subjects with isolated LBBB (group III) was made.
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Conclusion & Impact:Comparison with group I and group II patients showed that there was a similarity between LV systolic function parameters while the diastolic function parameters were statistically different (E/A, p=0.004; EAR, p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

We designed this study to examine the effect of left bundle-branch block (LBBB) on systolic and diastolic functions of the left ventricle (LV) in patients with heart failure and in subjects with isolated LBBB. Methods: A comparison between 36 patients with heart failure and LBBB (group I), 36 patients with heart failure without LBBB (group II) and 41 subjects with isolated LBBB (group III) was made. Coronary angiography was performed in all patients with group I and group II, and in 20 patients of group III. LV end-diastolic pressure was calculated. Echocardiography was performed in all patients. LV ejection fraction and mean rate of circumferential shortening were calculated. The following Doppler parameters were also evaluated: peak rapid filling velocity (E wave), peak atrial filling velocity (A wave), E and A wave integrals, E wave acceleration time, deceleration time (EDT) and rates (EAR and EDR), the E/A ratio and its integral, and diastolic flow time (DT). The ejection time (ET), isovolumetric relaxation time (IRT) and preejection period were measured using the aortic and mitral flow velocities. Results: LV end-diastolic pressure was calculated as 28±4 mmHg in group I, 22±5 mmHg in group II, and: 15±3 mmHg in group III. Although the systolic function parameters in group-III patients were different, the diastolic function parameters were found to be quite similar in both patients with group II and III. Comparison with group I and group II patients showed that there was a similarity between LV systolic function parameters while the diastolic function parameters were statistically different (E/A, p=0.004; EAR, p

Özet

Kalp yetersizliği olanlarda ve normal şahıslarda sol ventrikülün (SV) sistolik ve diyastolik fonksiyonları üzerine sol dal blokunun (LBBB) etkisini araştırmak için bu çalışmayı planladık. Metot: Kalp yetersizliği ve LBBB olan 36 (grup I), kalp yetersizliği olan ve LBBB olmayan 36 (grup II) ve izole LBBB olan 41 (grup III) hasta grubunun karşılaştırması yapıldı. Grup I ve grup II'deki tüm hastalara, grup III'deki 20 hastaya koroner anjiyografi uygulandı ve SV diyastol sonu basınçları ölçüldü. Tüm hastalara ekokardiyografi yapıldı. Sol ventikül ejeksiyon fraksiyonu ve ortalama dairesel lif kısalma hızı ölçüldü. Aşağıdaki Doppler ekokardiyografi parametreleri değerlendirildi; mitral kan akımı üzerinden zirve hızlı doluş hızı (E dalgası), zirve atriyal doluş hızı (A dalgası), E ve A dalga integralleri, E dalgası akselerasyon zamanı ve deselerasyon zamanı (EDZ) ile hızları (EAH ve EDH), E/A ve integralleri oranı, diyastolik akım zamanı (DZ); ayrıca aort ve mitral akım hızları eş zamanlı kaydedilerek ejeksiyon zamanı, izovolümetrik relaksasyon zamanı (İRZ) ve preejeksiyon periyodu ölçüldü. Bulgular: SV diyastol sonu basınçları grup I, II ve III'de sırasıyla 28±4, 22±5, 15±3 mmHg olarak ölçüldü. Grup III hastalarında sistolik fonksiyon parametreleri farklı olmasına rağmen grup II ve III hastalarında diyastolik fonksiyon parametreleri oldukça benzer bulundu. Grup I ve II'nin karşılaştırılması, SV sistolik fonksiyon parametreleri benzer olmasına karşın diyastolik fonksiyon parametrelerinin istatistiksel olarak farklı olduğunu gösterdi. (E/A, p=0.004; EAH, p

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Cite This Article

ÖZDEMİR, K., GÖK, H., TOKAÇ, M., KORKUT, B., ALTUNKESER, B. B. (2022). Effect of left bundle-branch block on systolic and diastolic left ventricular functions with and without heart failure. Türk Kardiyoloji Derneği Arşivi, Cilt: 29 - Sayı: 1, 40–46. https://ajindex.com/articles/633981

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