AI Summary & Key Takeaways
AI InsightOverall mortality and early mortality rates were 42.9% and 38.1%, respectively.
📌 3 Key Takeaways
Abstract
Postinfarction ventricular septal defect (VSR) developing in 1-2% of patients is a serious complication with high mortality rates. In this study, VSRs repaired surgically were evaluated retrospectively with clinical and echocardiographic findings to analyse variables affecting mortality and morbidity as well as surgical technique. The preoperative, perioperative, and postoperative early and mid-term follow-up data of 21 patients with VSR who underwent surgical repair from 1996 through 2001, were evaluated. Preoperative coronary angiography, cardiac catheterization were performed in all patients. Preoperative and postoperative control echocardiography were also performed in all patients but two patients who died perioperatively. Follow-up data after the discharge of these patients were obtained via monthly periodical examinations in the first 6 months, and thereafter via telephone interviews. The mean follow-up time of surviving 13 patients was 27.62±22.60 (2-67) months. Overall mortality and early mortality rates were 42.9% and 38.1%, respectively. Postoperative complications were observed in 13 (68.4%) patients. The most frequently encountered complication was congestive heart failure developed in 8 patients. Advanced age and cardiogenic shock were significant risk factors for postoperative renal failure and congestive heart failure. Overall morbidity was significantly high in patients with preoperative QP/QS>2. Advanced age, anterior MI, ejection fraction (LVEF)
Özet
Akut miyokard infarktüsü sonrası ventriküler septal rüptür (VSR) %1-2 hastada oluşan çok yüksek mortalite ile seyreden bir komplikasyondur. Çalışmamızda cerrahi tedavi uygulanan postinfarktüs VSR'ler cerrahi teknik ve mortalite ile morbiditeye etkili risk faktörleri açısından klinik ve ekokardiyografik bulguları ile retrospektif olarak değerlendirilmiştir. Merkezimizde 1996-2001 arasında akut postinfarktüs VSR saptanan 21 olguya cerrahi tedavi uygulanmıştır. Bütün olgulara preoperatif koroner anjiografi, sol ventrikülografi ve perioperatif olarak kaybedilen iki olgu haricindeki bütün olgulara preoperatif ve postoperatif ekokardiyografi yapılmıştır. Olgular postoperatif ilk 6 ayda poliklinik kontrolleri, sonrasında telefon görüşmeleri ile izlenmişlerdir. Postoperatif kontrolleri yapılan toplam 13 olgunun ortalama izlem süresi 27.6±22.6 (2-67) aydır. Toplam mortalite 9 (%42.9) olgu olup, 8 (%38.1) olgu erken dönem hastane mortalitesidir. Postoperatif dönemde yaşayan 19 olgudan 13'ünde (%68.4) 30 komplikasyon gelişmiştir. En sık karşılaşılan 8 (%42.1) olguda gelişen KKY'dir. İleri yaş ve kardiyojenik şok ile postoperatif renal yetersizlik ve KKY ilişkisi anlamlı bulunmuştur. Preoperatif şantı fazla (>2) olan olgularda genel morbidite anlamlı derecede yüksek bulunmuştur. İleri yaş, ön yüz lokalizasyonlu MI, LVEF (