Kalp hızı türbülansı uzun QT sendromunun iyi bir öngördürücüsü değil mi?

The long QT syndrome (LQTS) is associated with recurrent syncope, ventricular arrhythmias and sudden death. It was shown that heart rate turbulence (HRT) predicts mortality and sudden cardiac death following myocardial infarction. In this study our aim is to examine HRT parameters in sudden cardiac death survivors with LQTS. Four patients with LQTS (mean age 12.5±1,8) were included in the study. Their 24 hours ambulatory electrocardiograms (ECGs) were recorded with Reynolds recorder device in a drug free period. Holter recordings were analyzed with Reynolds Medical Pathfinder Software Version V8.255. HRT was determined with HRT! View Version 0.60-0.1 software program and turbulence onset (TO) and turbulence slope (TS) were determined. In Holter recordings all patients where in sinus rhythm and atrial fibrillation, ventricular and supraventricular tachycardia attacks were not observed. TO and TS values of patients were found within normal range. TO values were lower than 0 and TS values were bigger than 2.5. I n conclusion, HRT has no predictive value for assessing mortality and sudden death following myocardial infarction in patients with LQTS. HRT may not be a good risk predictor for LQTS.

Özet

Uzun QT sendromu (UQTS) elektrokardiyogramda QT uzaması, klinikte tekrarlayan senkop atakları, ventriküler aritmiler ve ani ölümle seyreden bir hastalıktır. Kalp hızı türbülansının (HRT), miyokard infarktüsü sonrasında mortaliteyi ve ani ölümü saptamada güçlü bir ön belirleyici olduğu saptanmıştır. Bizde çalışmamızda ani ölümlerin gözlendiği UQTS'lu hastalarda HRT parametrelerini araştırdık. UQTS olan 4 erkek hasta (ort yaş 12.5±1.8) çalışmaya kabul edildi. Hastaların ilaç kullanmadıkları dönemde 24 saatlik ambulatuvar elektrokardiyogram kayıtları, Reynolds marka kaydedicilerle kaydedildi. Aritmi analizi Reynolds Medical Pathfinder Software Version V8.255 ile yapıldı. HRT analizi HRT! View Version 0.60-0.1 software program yapılarak, "turbulence onset (TO)" ve "turbulence slope (TS)" değerleri belirlendi. Holter kayıtlarında, tüm hastalar sinüs ritminde idi, hiçbir hastada atriyal fibrilasyon, ventriküler ve supraventriküler taşikardi atağı gözlenmedi. Hastaların TO ve TS değerleri normal sınırlarda bulundu. Tüm hastaların TO değerleri 0 dan küçük, TS değerleri 2.5 dan büyüktü. Sonuç olarak HRT, UQTS'lu hastalarda ani ölümü ve mortaliteyi saptamada, miyokard infarktüsünde olduğu gibi belirleyici görünmemektedir

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Cite This Article

ÇELİK, A., KİLİT, C., BARUTÇU, İ., ONRAT, E., MELEK, M., KAYA, D., KERPETEN, K., ESEN, A. M. (2022). Kalp hızı türbülansı uzun QT sendromunun iyi bir öngördürücüsü değil mi?. Türk Kardiyoloji Derneği Arşivi, Cilt: 31 - Sayı: 12, 770–775. https://ajindex.com/articles/633897

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