Journals / Türk Kardiyoloji Derneği Arşivi / 2004 / Cilt: 32 - Sayı: 6

Prevalance of the metabolic syndrome and its effect on inhospital outcomes in patients with unstable angina pectoris

Kararsız angina pektorisli hastalarda metabolik sendrom sıklığı ve hastane içi sonuçlara etkisi

Pages
356–363
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In conclusion, MS existed in a very high prevalence amory patients with unstable angina pectoris.

📌 3 Key Takeaways

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Objective & Hypothesis:The metabolic syndrome (MS) is a public health problem which is becoming increasingly common worldwide.
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Key Findings & Data:According to TEKHARF study database, MS was responsible for 53% of patients with established coronary heart disease (CHD) indicating its role es an important public health insure in Turkish adults.
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Conclusion & Impact:In conclusion, MS existed in a very high prevalence amory patients with unstable angina pectoris.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The metabolic syndrome (MS) is a public health problem which is becoming increasingly common worldwide. According to TEKHARF study database, MS was responsible for 53% of patients with established coronary heart disease (CHD) indicating its role es an important public health insure in Turkish adults. We studied prevalance, component distribution of the MS and its relationship with CHD and high-sensitivity C-reactive protein (hsCRP) in patients with unstable angina pectoris. Study population consisted of 100 hospitalized patients with unstable angina pectoris (M 77, F 23; mean age 60.33±9.48 yrs). These patients had not received lipid-lowering therapy before hospitalization. Components of the MS were screened and apoA, apoB and hsCRP levels were measured in all patients. Body mass index was calculated and all patients underwent coronary angiography. The number of coronary arteries with critical stenosis was determined. MS existed in 57% of patients. MS prevalance was 53% in men and 69% in women. Among components of the MS, most frequent three components were low HDL-cholesterol levels (81%), hypertriglyceridemia (63%) and hypertension (53%) in men and abdominal obesity (waist circumference >88 cm) (91%), low HDL-cholesterol levels (82%) and hypertension (65%) in women respectively. Between MS and non-MS groups; one, two, three vessels disease and hsCRP levels were not statistically significant (p>0.05). The geometric mean values of hsCRP increased in relation to the number of diseased coronary arteries. In conclusion, MS existed in a very high prevalence amory patients with unstable angina pectoris. The component distribution of the MS varied somew hat between male and females. Increased levels of hsCRP were measured in patients with unstable angina pectoris, but MS does not contribute to this augmentation.

Özet

Metabolik sendrom (MS), tüm dünyada giderek yaygınlaşan bir halk sağlığı sorunudur. TEKHARF çalışması veritabanına göre koroner kalp hastalığı (KKH) gelişiminin %53'ünden sorumlu tutulan MS, Türk toplumu için de oldukça önemli bir problemdir. Biz çalışmamızda, kararsız angina pektorisli hastalarda MS sıklığını, MS unsurlarının dağılımını, MS'un KKH ve yüksek duyarlıklı C-reaktif protein (hsCRP) ile ilişkisini araştırdık. Çalışmaya hastanede yatan ve öncesinde antilipidemik ilaç kullanmayan 100 kararsız angina pektorisli hasta dahil edildi (77 erkek, 23 kadın; ort. yaş 60.33±9.48 yıl). Tüm hastalarda MS unsurları tarandı, apoA, apoB ve hsCRP ölçümleri yapıldı. Beden kitle indeksleri hesaplandı ve hastaların tümüne koroner anjiyografi uygulanarak kritik darlık gösteren koroner damarların sayısı belirlendi.Hastaların %57'sinde MS saptandı. MS sıklığı erkeklerde %53 iken kadınlarda %69 olarak belirlendi. Erkek bireylerde en sık görülen üç unsur sırasıyla HDL-K düşüklüğü (%81), hipertrigliseridemi (%63) ve hipertansiyon (%53) iken kadınlardaki sıralama; artmış bel çevresi (%91), HDL-K düşüklüğü (%82) ve hipertansiyon (%65) şeklinde idi. Ayrıca MS'u olan ve olmayan gruplar arasında tek, iki, üç damar tutulumu ve hsCRP düzeyleri açısından anlamlı fark gözlenmedi (p>0.05). Hasta damar sayısı arttıkça hsCRP geometrik ortalama değerlerinin de arttığı görüldü Sonuç olarak MS, kararsız angina pektorisli hasta grubunda oldukça yüksek oranda tespit edildi. MS unsurlarının dağılımı erkek ve kadın hastalarda farklılık gösterdi. hsCRP değerlerinin kararsız angina pektorisli hastalarda arttığı, MS'un buna ek katkı yapmadığı belirlendi.

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Cite This Article

ÇAKMAK, M., ÇAKMAK, N., SAYAR, N., ERDİNLER, İ., AKYOL, A., OĞUZ, E., GÜRKAN, K., EKSİK, A., ALPER, A. T. (2022). Prevalance of the metabolic syndrome and its effect on inhospital outcomes in patients with unstable angina pectoris. Türk Kardiyoloji Derneği Arşivi, Cilt: 32 - Sayı: 6, 356–363. https://ajindex.com/articles/633829

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