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Journals / Türk Kardiyoloji Derneği Arşivi / 2005 / Cilt: 33 - Sayı: 6

The incidence of nondipping state in normotensive patients with coronary slow flow and its relationship with prognosis

Koroner yavaş akım saptanan normotansif hastalarda nondipper durum sıklığı ve bunun prognoz ile ilişkisi

Kenan DURNA
Erdoğan YAŞAR
Mustafa YAZICI
Mahmut ŞAHİN
Sabri DEMİRCAN
Pages
319–325
Publication Date
2022-11-05
DOI
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The results were compared with those of 44 subjects (18 females, 26 males; mean age 55 years) with normal coronary flow.Results: The number of nondippers compared to dippers was significantly higher in the CSF group (n=35, 68.6% vs n=16, 31.4%, p

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Objective & Hypothesis:Objectives: We investigated the frequency of nondipping pattern, which is thought to be related with increased sympathetic activity, and its influence on the pathogenesis and prognosis of patients with coronary slow flow.Study design: The study included 51 normotensive patients (22 females, 29 males; mean age 54 years) in whom coronary slow flow (CSF) was diagnosed by coronary angiography and TIMI (thrombolysis in myocardial infarction) frame count.
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Key Findings & Data:Venous blood samples were obtained at the same hours of the day to determine noradrenaline and adrenaline levels and 24-hour ambulatory blood pressure monitoring was performed.
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Conclusion & Impact:The results were compared with those of 44 subjects (18 females, 26 males; mean age 55 years) with normal coronary flow.Results: The number of nondippers compared to dippers was significantly higher in the CSF group (n=35, 68.6% vs n=16, 31.4%, p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: We investigated the frequency of nondipping pattern, which is thought to be related with increased sympathetic activity, and its influence on the pathogenesis and prognosis of patients with coronary slow flow.Study design: The study included 51 normotensive patients (22 females, 29 males; mean age 54 years) in whom coronary slow flow (CSF) was diagnosed by coronary angiography and TIMI (thrombolysis in myocardial infarction) frame count. Venous blood samples were obtained at the same hours of the day to determine noradrenaline and adrenaline levels and 24-hour ambulatory blood pressure monitoring was performed. At least 10% of sleep-related nocturnal decrease in systolic and diastolic pressures was accepted as dipping, while decreases below 10% were defined as nondipping. The results were compared with those of 44 subjects (18 females, 26 males; mean age 55 years) with normal coronary flow.Results: The number of nondippers compared to dippers was significantly higher in the CSF group (n=35, 68.6% vs n=16, 31.4%, p

Özet

Amaç: Artmış sempatik aktiviteyle ilişkili olduğu düşünülen nondipper durumun, koroner yavaş kan akımı (KYA) saptanan hastalarda görülme sıklığı ve bunun hastalığın patogenezi ve prognozu üzerine etkileri araştırıldı.Çalışma planı: Çalışmaya, koroner anjiyografi ve TIMI (thrombolysis in myocardial infarction) kare sayısı yöntemiyle KYA tanısı konan 51 normotansif hasta (22 kadın, 29 erkek; ort. yaş 54) alındı. Adrenalin ve noradrenalin düzeylerinin ölçümü için günün aynı saatlerinde venöz kan örnekleri alındı. Tüm hastaların 24 saatlik ambulatuvar kan basınçları kaydedildi. Ortalama sistolik ve diyastolik kan basıncı değerlerinin gece, gündüze göre %10’dan fazla düşmesi dipper, %10’dan daha az veya hiç düşmemesi nondipper olarak kabul edildi. Sonuçlar, koroner akımı normal bulunan 44 olgunun (18 kadın, 26 erkek; ort. yaş 55) sonuçlarıyla karşılaştırıldı.Bulgular: Koroner yavaş akım saptanan grupta nondipper durumu (n=35, %68.6) dipper durumdan (n=16, %31.4), kontrol grubunda ise dipper (n=41, %93.2) nondipper (n=3, %6.8) durumdan anlamlı derecede fazlaydı (sırasıyla, p

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Cite This Article

DURNA, K., YAŞAR, E., YAZICI, M., ŞAHİN, M., DEMİRCAN, S. (2022). The incidence of nondipping state in normotensive patients with coronary slow flow and its relationship with prognosis. Türk Kardiyoloji Derneği Arşivi, Cilt: 33 - Sayı: 6, 319–325. https://ajindex.com/articles/633744

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