SavedAdd your journal

Journals / Türk Kardiyoloji Derneği Arşivi / 2006 / Cilt: 34 - Sayı: 2

Evaluation of left atrial appendage functions by transesophageal echocardiography in patients with hyperthyroidism

Hipertiroidili hastalarda transözofajiyal ekokardiyografiyle sol atriyum apendiks fonksiyonlarının değerlendirilmesi

Erhan TENEKECİOĞLU
Tahsin BOZAT
Süleyman BİNİCİ
Kenar Selma TİRYAKİOĞLU
Hasan ARI
M. Vedat KOCA
M. Cem BAŞEL
Hakan ÖZKAN
Pages
79–83
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Similarly, compared to group IV, group II had significantly higher emptying (0.7 m/s vs 0.4 m/s) and filling (0.7 m/s vs 0.4 m/s) velocities (p=0.0001).Conclusion: Our results show that the contractile functions of the left atrial appendage are preserved in patients with hyperthyroidism, suggesting a lower risk for hemostasis and thrombus formation.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objectives: We evaluated the contractile function of the left atrial appendage, an important anatomical structure in the pathogenesis of systemic embolism, by transesophageal echocardiography in patients with hyperthyroidism.Study design: Transthoracic and transesophageal echocardiography were performed in four patient groups having the following features: hyperthyroid patients with atrial fibrillation (group I, n=23), hyperthyroid patients with sinus rhythm (group II, n=22), control patients with atrial fibrillation (group III, n=12), and control patients with sinus rhythm (group IV, n=12).
📊
Key Findings & Data:Transthoracic and transesophageal echocardiography findings were compared between groups I and III, and groups II and IV.Results: No significant differences were found between the groups with respect to standard transthoracic echocardiography parameters.
💡
Conclusion & Impact:Similarly, compared to group IV, group II had significantly higher emptying (0.7 m/s vs 0.4 m/s) and filling (0.7 m/s vs 0.4 m/s) velocities (p=0.0001).Conclusion: Our results show that the contractile functions of the left atrial appendage are preserved in patients with hyperthyroidism, suggesting a lower risk for hemostasis and thrombus formation.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: We evaluated the contractile function of the left atrial appendage, an important anatomical structure in the pathogenesis of systemic embolism, by transesophageal echocardiography in patients with hyperthyroidism.Study design: Transthoracic and transesophageal echocardiography were performed in four patient groups having the following features: hyperthyroid patients with atrial fibrillation (group I, n=23), hyperthyroid patients with sinus rhythm (group II, n=22), control patients with atrial fibrillation (group III, n=12), and control patients with sinus rhythm (group IV, n=12). Transthoracic and transesophageal echocardiography findings were compared between groups I and III, and groups II and IV.Results: No significant differences were found between the groups with respect to standard transthoracic echocardiography parameters. In transesophageal echocardiography, the emptying (0.5 m/s vs 0.3 m/s, p=0.028) and filling (0.5 m/s vs 0.4 m/s, p=0.015) velocities of the left atrial appendage were found to be significantly higher in group I than in group III. Similarly, compared to group IV, group II had significantly higher emptying (0.7 m/s vs 0.4 m/s) and filling (0.7 m/s vs 0.4 m/s) velocities (p=0.0001).Conclusion: Our results show that the contractile functions of the left atrial appendage are preserved in patients with hyperthyroidism, suggesting a lower risk for hemostasis and thrombus formation.

Özet

Amaç: Hipertiroidili hastalarda, transözofajiyal ekokardiyografiyle, sistemik emboli için önemli bir anatomik yapı olan sol atriyum apendiksinin (SAA) kontraktil fonksiyonu değerlendirildi.Çalışma planı: Çalışmada aşağıdaki özelliklere sahip dört hasta grubu transtorasik ve transözofajiyal ekokardiyografiyle incelendi: Atriyal fibrilasyonlu (AF) ve hipertiroidili hastalar (grup I, n=23), sinüs ritmindeki hipertiroidili hastalar (grup II, n=22), AF’li kontrol grubu hastaları (grup III, n=12) ve sinüs ritmindeki kontrol grubu hastaları (grup IV, n=12). Grup I ile grup III’ün, grup II ile grup IV’ün transtorasik ve transözofajiyal ekokardiyografi bulguları karşılaştırıldı.Bulgular: Standart transtorasik ekokardiyografi parametreleri açısından gruplar arasında anlamlı farklılık yoktu. Transözofajiyal ekokardiyografiyle yapılan değerlendirmede, grup I’de ölçülen ortalama SAA boşalma (0.5 m/s) ve doluş (0.5 m/s) hızları, grup III’ün değerlerinden (sırasıyla 0.3 m/s, p=0.028 ve 0.4 m/s, p=0.015) daha yüksek bulundu. Grup II’de de, grup IV ile karşılaştırıldığında, SAA boşalma (0.7 m/s ve 0.4 m/s, p=0.0001) ve doluş hızları (0.7 m/s ve 0.4 m/s, p=0.0001) daha yüksek bulundu.Sonuç: Bulgularımız, hipertiroidili hastalarda SAA’nın kontraktil fonksiyonlarının korunduğunu göstermektedir. Bu veriler, hipertiroidili hastalarda SAA’da staz ve trombüs oluşma riskinin az olabileceğini düşündürmektedir.

🔖

Cite This Article

TENEKECİOĞLU, E., BOZAT, T., BİNİCİ, S., TİRYAKİOĞLU, K. S., ARI, H., KOCA, M. V., BAŞEL, M. C., ÖZKAN, H. (2022). Evaluation of left atrial appendage functions by transesophageal echocardiography in patients with hyperthyroidism. Türk Kardiyoloji Derneği Arşivi, Cilt: 34 - Sayı: 2, 79–83. https://ajindex.com/articles/633730

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (12)

  1. Fuster V, Ryden LE, Asinger RW, Cannom DS, Crijns HJ, Frye RL, et al. ACC/AHA/ESC guidelines for the management of patients with atrial fibrillation. A report of the American College of Cardiology/ American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines and Policy Conferences (Committee to develop guidelines for the management of patients with atrial fibrillation) developed in collaboration with the North American Society of Pacing and Electrophysiology. Eur Heart J 2001; 22:1852-923
  2. Wolf PA, Abbott RD, Kannel WB. Atrial fibrillation as an independent risk factor for stroke: the Framingham Study. Stroke 1991;22:983-8
  3. Li YH, Lai LP, Shyu KG, Hwang JJ, Ma HM, Ko YL, et al. Clinical implications of left atrial appendage function: its influence on thrombus formation. Int J Cardiol 1994;43:61-6
  4. Transesophageal echocardiographic correlates of thromboembolism in high risk patients with nonvalvular atrial fibrillation. The Stroke Prevention in Atrial Fibrillation Investigators Committee on Echocardiography. Ann Intern Med 1998;128:639-47
  5. Mugge A, Kuhn H, Nikutta P, Grote J, Lopez JA, Daniel WG. Assessment of left atrial appendage function by biplane transesophageal echocardiography in patients with nonrheumatic atrial fibrillation: identification of a subgroup of patients at increased embolic risk. J Am Coll Cardiol 1994;23:599-607
  6. Fatkin D, Kelly RP, Feneley MP. Relations between left atrial appendage blood flow velocity, spontaneous echocardiographic contrast and thromboembolic risk in vivo. J Am Coll Cardiol 1994;23:961-9
  7. Garcia-Fernandez MA, Torrecilla EG, San Roman D, Azevedo J, Bueno H, Moreno MM, et al. Left atrial appendage Doppler flow patterns: implications on thrombus formation. Am Heart J 1992;124:955-61
  8. Bar-Sela S, Ehrenfeld M, Eliakim M. Arterial embolism in thyrotoxicosis with atrial fibrillation. Arch Intern Med 1981;141:1191-2
  9. Petersen P, Hansen JM. Stroke in thyrotoxicosis with atrial fibrillation. Stroke 1988;19:15-8
  10. Klein I, Ojamaa K. Thyroid hormone and the cardiovascular system. N Engl J Med 2001;344:501-9
  11. Kiss E, Jakab G, Kranias EG, Edes I. Thyroid hormone-induced alterations in phospholamban protein expression. Regulatory effects on sarcoplasmic reticulum Ca2+ transport and myocardial relaxation. Circ Res 1994;75:245-51
  12. Dillmann WH. Biochemical basis of thyroid hormone action in the heart. Am J Med 1990;88:626-30.