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Journals / Türk Kardiyoloji Derneği Arşivi / 2006 / Cilt: 34 - Sayı: 8

The relationship of high plasma levels of atrial and brain natriuretic peptides with disease severity in mitral valve stenosis

Mitral kapak darlığında yüksek plazma atriyal ve beyin natriüretik peptid düzeylerinin hastalık ciddiyeti ile ilişkisi-

Nevzat USLU
Zekeriya NURKALEM
İlhan İlker AVCI
Hasan O. ÖZER
İbrahim SARI
Zübeyir ACAR
Ahmet L. ORHAN
Mehmet EREN
Şevket GÖRGÜLÜ
Pages
484–488
Publication Date
2022-11-05
DOI
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Results: Compared with controls, patients with MS had significantly higher plasma ANP (6±4 ng/ml vs 45±33 ng/ml) and BNP (12±7.2 pg/ml vs 79±55 pg/ml) levels (p

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Objective & Hypothesis:Objectives: We aimed to determine plasma levels of atrial (ANP) and brain (BNP) natriuretic peptides in patients with mitral stenosis (MS), and to seek clinical and echocardiographic correlations with these peptides.
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Key Findings & Data:Study design: Thirty-eight patients (33 females, 5 males; mean age 44±9 years) with MS and 12 healthy controls (10 females, 2 males; mean age 46±7 years) were examined by echocardiography.
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Conclusion & Impact:Results: Compared with controls, patients with MS had significantly higher plasma ANP (6±4 ng/ml vs 45±33 ng/ml) and BNP (12±7.2 pg/ml vs 79±55 pg/ml) levels (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: We aimed to determine plasma levels of atrial (ANP) and brain (BNP) natriuretic peptides in patients with mitral stenosis (MS), and to seek clinical and echocardiographic correlations with these peptides. Study design: Thirty-eight patients (33 females, 5 males; mean age 44±9 years) with MS and 12 healthy controls (10 females, 2 males; mean age 46±7 years) were examined by echocardiography. All the patients were in sinus rhythm. Venous blood samples were taken to measure ANP and BNP levels. Results: Compared with controls, patients with MS had significantly higher plasma ANP (6±4 ng/ml vs 45±33 ng/ml) and BNP (12±7.2 pg/ml vs 79±55 pg/ml) levels (p

Özet

Amaç: Mitral kapak darlığı (MKD) olan hastalarda A-tip ve B-tip natriüretik peptidlerin (ANP ve BNP) düzeyleri belirlendi, bu düzeylerin klinik ve ekokardiyografik parametrelerle ilişkileri incelendi. Çalışma planı: İzole MKD saptanan ve sinus ritmindeki 38 hasta (33 kadın, 5 erkek; ort. yaş 44±9) ve sağlıklı bireylerden oluşan 12 kişide (10 kadın, 2 erkek; ort. yaş 46±7) ekokardiyografik inceleme yapıldı ve ANP ve BNP düzeylerini belirlemek için kan örnekleri alındı. Bulgular: Hasta grubunda plazma BNP ve ANP düzeyleri kontrol grubuna göre anlamlı derecede yüksek bulundu (BNP için sırasıyla, 79±55 pg/ml ve 12±7.2 pg/ml; ANP için 45±33 ng/ml ve 6±4 ng/ml; p

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Cite This Article

USLU, N., NURKALEM, Z., AVCI, İ. İ., ÖZER, H. O., SARI, İ., ACAR, Z., ORHAN, A. L., EREN, M., GÖRGÜLÜ, Ş. (2022). The relationship of high plasma levels of atrial and brain natriuretic peptides with disease severity in mitral valve stenosis. Türk Kardiyoloji Derneği Arşivi, Cilt: 34 - Sayı: 8, 484–488. https://ajindex.com/articles/633699

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