Journals / Türk Kardiyoloji Derneği Arşivi / 2006 / Cilt: 34 - Sayı: 7

The relationship between plasma brain natriuretic peptide levels and left ventricular end-diastolic pressure and the extent of coronary artery involvement in chronic coronary artery disease

Kronik koroner kalp hastalığında serum beyin natriüretik peptid düzeyi ile sol ventrikül diyastol sonu basıncı ve hastalığın derecesi arasındaki ilişki

Pages
413–418
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Vessel involvement was significantly correlated with BNP (r=0.463, p

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: Recent studies suggest that brain natriuretic peptide (BNP) is associated with the prognosis of coronary heart disease.
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Key Findings & Data:Study design: The study included 100 patients (30 women, 70 men; mean age 56 years; range 37 to 78 years) who underwent coronary angiography for definite or suspected coronary artery disease.
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Conclusion & Impact:Vessel involvement was significantly correlated with BNP (r=0.463, p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: Recent studies suggest that brain natriuretic peptide (BNP) is associated with the prognosis of coronary heart disease. We studied the relationship between BNP and left ventricular (LV) end-diastolic pressure and the number of involved coronary arteries in patients with chronic coronary artery disease. Study design: The study included 100 patients (30 women, 70 men; mean age 56 years; range 37 to 78 years) who underwent coronary angiography for definite or suspected coronary artery disease. Before angiography, baseline serum samples were obtained for plasma BNP, and LV end-diastolic pressure was measured. The patients were classified in three groups as normal (n=35), one-vessel disease (n=16) and multivessel disease (n=49). Results: The incidence of diabetes mellitus and the levels of BNP and fasting blood glucose were significantly higher, and LV end-diastolic pressure and the mean heart rate were significantly increased in multivessel disease. Vessel involvement was significantly correlated with BNP (r=0.463, p

Özet

Amaç: Son yıllarda beyin natriüretik peptidin (BNP) koroner kalp hastalığında (KKH) prognozla ilişkili olduğunu gösteren çalışmalar vardır. Bu çalışmada yüksek BNP seviyesinin, KKH’li semptomsuz hastalarda sol ventrikül diyastol sonu basıncı (DSB) ve anjiyografik olarak hasta damar sayısı ile ilişkisi araştırıldı. Çalışma planı: Çalışmaya koroner arter hastalığı tanısı veya şüphesiyle koroner anjiyografi yapılan 100 hasta (30 kadın, 70 erkek; ort. yaş 56; dağılım 37-78) alındı. Hastalardan BNP ve diğer laboratuvar ölçümleri için kan alındıktan sonra sol ventrikül basınçları ölçüldü ve koroner anjiyografi uygulandı. Anjiyografi sonuçlarına göre hastalar, normal (n=35), tek damar hastalığı (n=16) ve çokdamar hastalığı (n=49) şeklinde üç gruba ayrıldı. Bulgular: Çokdamar hastalığı olan grupta diyabetes mellitus sıklığı, sol ventrikül DSB, BNP ve açlık kan şekeri düzeyleri diğer iki gruba göre anlamlı derecede daha yüksekti. Çokdamar hastalığı olan grupta ortalama kalp hızı, tek damar hastalığı grubuna göre daha yüksekti. Hasta damar sayısı ile BNP (r=0.463, p

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Cite This Article

SOYLU, Ö., SAN, İ., ORHAN, A. L., UYAREL, H., SAYAR, N., EREN, M., USLU, N., GÖRGÜLÜ, Ş., NURKALEM, Z., KARABULUT, A., SÜRGİT, Ö. (2022). The relationship between plasma brain natriuretic peptide levels and left ventricular end-diastolic pressure and the extent of coronary artery involvement in chronic coronary artery disease. Türk Kardiyoloji Derneği Arşivi, Cilt: 34 - Sayı: 7, 413–418. https://ajindex.com/articles/633663

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