Journals / Türk Kardiyoloji Derneği Arşivi / 2008 / Cilt: 36 - Sayı: 4

Clinical importance of cardiac troponins

Kardiyak troponinlerin klinik önemi

Pages
269–277
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this article, we reviewed the clinical syndromes associated with elevated cTn levels.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Cardiac troponins (cTn) are highly sensitive and specific markers of myocardial injury.
📊
Key Findings & Data:Elevated cTn levels have considerable significance in both prognosis and guidance of the therapy of acute coronary syndrome.
💡
Conclusion & Impact:In this article, we reviewed the clinical syndromes associated with elevated cTn levels.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Cardiac troponins (cTn) are highly sensitive and specific markers of myocardial injury. Elevated cTn levels have considerable significance in both prognosis and guidance of the therapy of acute coronary syndrome. Thus, cTn measurements are commonly utilized in coronary care units and emergency departments to diagnose acute coronary syndrome. However, it must be considered that cTn elevations may be seen in many diseases other than acute coronary syndrome. In this article, we reviewed the clinical syndromes associated with elevated cTn levels.

Özet

Kardiyak troponinler (cTn) miyokard hasarının oldukça duyarlı ve özgül göstergeleridir. Akut koroner sendromda, artmış cTn düzeyleri hem prognoz hem de tedavinin yönlendirilmesi açısından önem taşımaktadır. Bu nedenle, acil serviste ve yoğun bakım ünitelerinde akut koroner sendromun ayırıcı tanısında sıklıkla cTn düzeyi ölçümlerinden yararlanılmaktadır. Ancak, cTn yüksekliğinin akut koroner sendrom dışında diğer bazı klinik durumlarla da ilişkili olabileceği göz önünde bulundurulmalıdır. Bu derlemede artmış cTn düzeyleri ile ilişkili olabilecek klinik durumlar ele alındı.

🔖

Cite This Article

DİKER, E., ÇELEBİ, Ö. Ö., AYDOĞDU, S. (2022). Clinical importance of cardiac troponins. Türk Kardiyoloji Derneği Arşivi, Cilt: 36 - Sayı: 4, 269–277. https://ajindex.com/articles/633578

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (11)

  1. Adams JE 3rd, Abendschein DR, Jaffe AS. Biochemical markers of myocardial injury. Is MB creatine kinase the choice for the 1990s? Circulation 1993;88:750-63
  2. Alpert JS, Thygesen K, Antman E, Bassand JP. Myocardial infarction redefined-a consensus document of The Joint European Society of Cardiology/American College of Cardiology Committee for the redefinition of myocardial infarction. J Am Coll Cardiol 2000;36:959-69
  3. Kavsak PA, MacRae AR, Lustig V, Bhargava R, Vandersluis R, Palomaki GE, et al. The impact of the ESC/ACC redefinition of myocardial infarction and new sensitive troponin assays on the frequency of acute myocardial infarction. Am Heart J 2006;152:118-25
  4. Braunwald E, Antman EM, Beasley JW, Califf RM, Cheitlin MD, Hochman JS, et al. ACC/AHA 2002 guideline update for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction-summary article: a report of the American College of Cardiology/American Heart Association task force on practice guidelines (Committee on the Management of Patients With Unstable Angina). J Am Coll Cardiol 2002;40:1366-74
  5. Bassand JP, Hamm CW, Ardissino D, Boersma E, Budaj A, Fernández-Aviles F, et al. Guidelines for the diagnosis and treatment of non-ST-segment elevation acute coronary syndromes. Task Force for Diagnosis and Treatment of Non-ST-Segment Elevation Acute Coronary Syndromes of European Society of Cardiology. Eur Heart J 2007;28:1598-660
  6. Panteghini M, Pagani F, Yeo KT, Apple FS, Christenson RH, Dati F, et al. Evaluation of imprecision for cardiac troponin assays at low-range concentrations. Clin Chem 2004;50:327-32
  7. Panteghini M, Gerhardt W, Apple FS, Dati F, Ravkilde J, Wu AH. Quality specifications for cardiac troponin assays. Clin Chem Lab Med 2001;39:175-9
  8. Wu AH, Apple FS, Gibler WB, Jesse RL, Warshaw MM, Valdes R Jr. National Academy of Clinical Biochemistry Standards of Laboratory Practice: recommendations for the use of cardiac markers in coronary artery diseases. Clin Chem 1999;45:1104-21
  9. Fleming SM, O’Byrne L, Finn J, Grimes H, Daly KM. False-positive cardiac troponin I in a routine clinical population. Am J Cardiol 2002;89:1212-5
  10. Apple FS, Christenson RH, Valdes R Jr, Andriak AJ, Berg A, Duh SH, et al. Simultaneous rapid measurement of whole blood myoglobin, creatine kinase MB, and cardiac troponin I by the triage cardiac panel for detection of myocardial infarction. Clin Chem 1999;45:199-205
  11. Roger VL, Killian JM, Weston S