Journals / Türk Kardiyoloji Derneği Arşivi / 2015 / Cilt: 43 - Sayı: 2

Artmış eritrosit dağılım genişliği kararlı koroner arter hastalarında yetersiz koroner kollateral dolaşımı ile ilişkilidir

Increased level of red cell distribution width is associated with poor coronary collateral circulation in patients with stable coronary artery disease

Pages
123–130
Publication Date
2022-11-05
DOI
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In multivariate logistic regression analysis, elevated levels of RDW and LDL were found to be independent predictors of poor CCC (OR 1.73, 95% CI: 1.30-2.29p=0.01 and OR 1.01 95% CI 1.002-1.02; p=0.02, respectively)Conclusion: In the present study, poor CCC was found to be independently correlated with RDW, but not with any othehematological parameters in patients with stable CAD.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: Previous studies have shown the association between various hematological parameters and cardiovascular diseases, and their prognostic value.
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Key Findings & Data:Study design: 326 patients with stable coronary artery disease (CAD) were evaluated retrospectively.
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Conclusion & Impact:In multivariate logistic regression analysis, elevated levels of RDW and LDL were found to be independent predictors of poor CCC (OR 1.73, 95% CI: 1.30-2.29p=0.01 and OR 1.01 95% CI 1.002-1.02; p=0.02, respectively)Conclusion: In the present study, poor CCC was found to be independently correlated with RDW, but not with any othehematological parameters in patients with stable CAD.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: Previous studies have shown the association between various hematological parameters and cardiovascular diseases, and their prognostic value. In this study, we compared red cell distribution width (RDW), neutrophil lymphocyte ratio (NLR) and mean platelet volume (MPV) measurementamong patients with poor coronary collateral circulation (CCCand well-developed CCC. Study design: 326 patients with stable coronary artery disease (CAD) were evaluated retrospectively. CCC was graded by using the Rentrop classification. The poor CCC group included patients with Rentrop 0-1 CCC, and the good CCC group included Rentrop 2-3 CCC. Results: There were 171 subjects (84% male; mean age 56.6±10.4 years) in the poor CCC group, and 155 subject(89% male; mean age 57.6±9.7 years) in the good CCC groupThe total number of vessels with >95% stenosis (1.1±0.5 vs1.0±0.4; p=0.64) and Gensini scores (84.4±38.8 vs. 83.3±37.4p=0.83) was not higher in the poor CCC group compared to the good CCC group. RDW was significantly higher in the pooCCC group compared to the good CCC group (14.19±1.36% vs13.89±1.19%; p=0.04). In multivariate logistic regression analysis, elevated levels of RDW and LDL were found to be independent predictors of poor CCC (OR 1.73, 95% CI: 1.30-2.29p=0.01 and OR 1.01 95% CI 1.002-1.02; p=0.02, respectively)Conclusion: In the present study, poor CCC was found to be independently correlated with RDW, but not with any othehematological parameters in patients with stable CAD.

Özet

Amaç: Hematolojik parametrelerin kardiyovasküler hastalıklarla ilişkisi ve prognostik önemleri gösterilmiştir. Bu çalışmada eritrosit dağılım genişliği (EDG), nötrofil lenfosit oranı (NLO) ve ortalama trombosit hacmi (OTH), yetersiz koroner kollateral dolaşımı (KKD) ve iyi gelişmiş KKD olan hastalarda karşılaştırılmıştır.Çalışma planı: Kararlı koroner arter hastalığı (KAH) olan 326 kişi geriye dönük olarak incelendi. KKD değerlendirilmesi Rentrop sınıflandırılması kullanılarak yapıldı. Yetersiz KKD grubuna Rentrop 0-1 kollateral dolaşımı olan, iyi gelişmiş KKD grubuna Rentrop 2-3 kollateral dolaşımı olan hastalar alındı.Bulgular: Yetersiz KKD grubunda 171 olgu (%84 erkek, ortalama yaş 56.6±10.4 yıl), iyi gelişmiş KKD grubunda 155 olgu (%89 erkek, ortalama yaş 57.6±9.7) bulunmaktaydı. Yetersiz KKD grubunda >%95den fazla darlık bulunan toplam damar sayısı (1.1±0.5 ve 1.0±0.4, p=0.64) ve Gensini skoru (84.4±38.8 ve 83.3±37.4; p=0.83) iyi gelişmiş KKD grubundan yüksek değildi. Hematolojik parametrelere bakıldığında, sadece EDG düzeyinin, yetersiz KKD grubunda anlamlı olarak daha yüksek olduğu bulundu (14.19±1.36 ve %13.89±%1.19, p=0.04). Çoklu değişkenli lojistik regresyon analizinde artmış EDG ve LDL-kolesterol düzeylerinin yetersiz KKDnin bağımsız belirleyicisi olduğu saptandı (sırasıyla, OR 1.73, %95 CI: 1.30-2.29, p=0.01 ve OR 1.01 %95 CI 1.002-1.02; p=0.02).Sonuç: Çalışmamızda hematolojik parametrelerden sadece EDG ile yetersiz KKD arasında bağımsız bir korelasyon olduğu saptanmıştır.

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Cite This Article

OKUYAN, E., KAYA, A., DİNÇKAL, M. H., GÜNGÖR, B., SIĞIRCI, S., ŞAHİN, İ., CAN, M. M., AVCI, İ. İ., KARABULUT, A., AYÇA, B. (2022). Artmış eritrosit dağılım genişliği kararlı koroner arter hastalarında yetersiz koroner kollateral dolaşımı ile ilişkilidir. Türk Kardiyoloji Derneği Arşivi, Cilt: 43 - Sayı: 2, 123–130. https://ajindex.com/articles/633523

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