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Journals / Türk Kardiyoloji Derneği Arşivi / 2008 / Cilt: 36 - Sayı: 6

Yavaş koroner akıma sahip hastalarda ortalama trombosit hacmi ve bunun klinik prezantasyonla ilişkisi

Mean platelet volume in patients with slow coronary flow and its relationship with clinical presentation

Betül ERER
Ahmet T. ALPER
Ahmet L. ORHAN
Aycan E. ZENCİRCİ
Hale Ü. AKSU
Dilek Ş. ERGÜN
Hale Y. YILMAZ
İbrahim SARI
Mehmet EREN
Zekeriya NURKALEM
Pages
363–367
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

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Results: The mean TIMI frame count was markedly increased in patients with SCF compared to controls (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: We investigated mean platelet volume (MPV) in patients with slow coronary flow (SCF) and its possible relationship with clinical presentation.
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Key Findings & Data:Study design: The study included 50 patients with SCF and otherwise normal coronary arteries and 22 patients (control group) with normal coronary arteries.
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Conclusion & Impact:Results: The mean TIMI frame count was markedly increased in patients with SCF compared to controls (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: We investigated mean platelet volume (MPV) in patients with slow coronary flow (SCF) and its possible relationship with clinical presentation. Study design: The study included 50 patients with SCF and otherwise normal coronary arteries and 22 patients (control group) with normal coronary arteries. In the SCF group, there were 26 patients with stable angina pectoris (SAP), and 24 patients with unstable angina pectoris (USAP). Coronary blood flow was measured using the TIMI frame count. To determine MPV, blood samples with K3 EDTA were processed after one hour of venipuncture. The relationship between MPV and SCF was sought. Results: The mean TIMI frame count was markedly increased in patients with SCF compared to controls (p

Özet

Amaç: Çalışmamızda yavaş koroner akımlı (YKA) hastalarda ortalama trombosit hacmi (OTH) ve bunun klinik prezantasyonla ilişkisi araştırıldı. Çalışma planı: Çalışmada YKA saptanan, koroner arterleri normal 50 hasta ve normal koroner anatomiye sahip 22 hasta (kontrol grubu) incelendi. Yavaş koroner akım grubunda 26 hastada kararlı angina, 24 hastada kararsız angina vardı. Koroner kan akımı TIMI kare sayısından hesaplandı. Ortalama trombosit hacmini belirlemek için, K3 EDTA’lı kan örnekleri kan alımından bir saat sonra çalışıldı. Ortalama trombosit hacmi ile YKA arasındaki ilişki araştırıldı.Bulgular: TIMI kare sayısı ortalaması YKA’lı hastalarda kontrollere göre anlamlı derecede yüksek bulundu (p

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Cite This Article

ERER, B., ALPER, A. T., ORHAN, A. L., ZENCİRCİ, A. E., AKSU, H. Ü., ERGÜN, D. Ş., YILMAZ, H. Y., SARI, İ., EREN, M., NURKALEM, Z. (2022). Yavaş koroner akıma sahip hastalarda ortalama trombosit hacmi ve bunun klinik prezantasyonla ilişkisi. Türk Kardiyoloji Derneği Arşivi, Cilt: 36 - Sayı: 6, 363–367. https://ajindex.com/articles/633518

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References (15)

  1. Martin JF, Bath PM, Burr ML. Influence of platelet size on outcome after myocardial infarction. Lancet 1991;338:1409-11
  2. Dalby Kristensen S, Milner PC, Martin JF. Bleeding time and platelet volume in acute myocardial infarction-a 2 year follow-up study. Thromb Haemost 1988;59:353-6
  3. Mathur A, Robinson MS, Cotton J, Martin JF, Erusalimsky JD. Platelet reactivity in acute coronary syndromes: evidence for differences in platelet behaviour between unstable angina and myocardial infarction. Thromb Haemost 2001;85:989-94
  4. Pizzulli L, Yang A, Martin JF, Luderitz B. Changes in platelet size and count in unstable angina compared to stable angina or non-cardiac chest pain. Eur Heart J 1998;19:80-4
  5. Yilmaz MB, Cihan G, Guray Y, Guray U, Kisacik HL, Sasmaz H, et al. Role of mean platelet volume in triagging acute coronary syndromes. J Thromb Thrombolysis 2008;26:49-54
  6. Martin JF, Shaw T, Heggie J, Penington DG. Measurement of the density of human platelets and its relationship to volume. Br J Haematol 1983;54:337-52
  7. Tambe AA, Demany MA, Zimmerman HA, Mascarenhas E. Angina pectoris and slow flow velocity of dye in coronary arteries-a new angiographic finding. Am Heart J 1972;84:66-71
  8. Yigit F, Sezgin AT, Demircan S, Tekin G, Erol T, Muderrisoglu H. Slow coronary flow is associated with carotid artery dilatation. Tohoku J Exp Med 2006; 209: 41-8
  9. Beltrame JF, Limaye SB, Horowitz JD. The coronary slow flow phenomenon-a new coronary microvascular disorder. Cardiology 2002;97:197-202
  10. Braunwald E, Jones RH, Mark DB, Brown J, Brown L, Cheitlin MD, et al. Diagnosing and managing unstable angina. Agency for Health Care Policy and Research. Circulation 1994;90:613-22
  11. Gibson CM, Cannon CP, Daley WL, Dodge JT Jr, Alexander B Jr, Marble SJ, et al. TIMI frame count: a quantitative method of assessing coronary artery flow. Circulation 1996;93:879-88
  12. Senaran H, Ileri M, Altinbas A, Kosar A, Yetkin E, Ozturk M, et al. Thrombopoietin and mean platelet volume in coronary artery disease. Clin Cardiol 2001; 24:405-8
  13. Rao AK, Goldberg RE, Walsh PN. Platelet coagulant activities in diabetes mellitus. Evidence for relationship between platelet coagulant hyperactivity and platelet volume. J Lab Clin Med 1984;103:82-92
  14. Jakubowski JA, Adler B, Thompson CB, Valeri CR, Deykin D. Influence of platelet volume on the ability of prostacyclin to inhibit platelet aggregation and the release reaction. J Lab Clin Med 1985;105:271-6
  15. Endler G, Klimes