Journals / Türk Kardiyoloji Derneği Arşivi / 2009 / Cilt: 37 - Sayı: 3

Clinical and epidemiological characteristics of infective endocarditis

Enfektif endokarditli olguların klinik ve epidemiyolojik özellikleri

Pages
182–186
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: The diagnosis and treatment of IE shouldbe designed taking into consideration that epidemiologic and clinical features of IE may differ from those ofindividual countries.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objectives: We evaluated the clinical and laboratorycharacteristics of patients with infective endocarditis (IE).Study design: During a five-year period (January2002-December 2006), 96 patients (56 men, 40 women;mean age 47±15 years; range 16 to 81 years) were treatedand followed for IE.
📊
Key Findings & Data:Blood samples were cultured in both aerobic andanaerobic media and incubated for 21 days.
💡
Conclusion & Impact:Conclusion: The diagnosis and treatment of IE shouldbe designed taking into consideration that epidemiologic and clinical features of IE may differ from those ofindividual countries.
🔬Design:Review & Systematic Survey
📍Scope:2006 Verileri
⚙️Variables:Domain Parameters

Abstract

Objectives: We evaluated the clinical and laboratorycharacteristics of patients with infective endocarditis (IE).Study design: During a five-year period (January2002-December 2006), 96 patients (56 men, 40 women;mean age 47±15 years; range 16 to 81 years) were treatedand followed for IE. All the patients underwent transthoracic and transesophageal echocardiography. Clinical andlaboratory characteristics of the patients were reviewed.All cases of prosthetic valve endocarditis were late-onsetIE. Blood samples were cultured in both aerobic andanaerobic media and incubated for 21 days. The diagnosisof IE was made according to the Duke criteria. Results: Male-to-female ratio was 1.4. The most common complaint on presentation was dyspnea (n=58,60.4%), followed by fever (n=20, 20.8%), and fatigue(n=16, 16.7%). The mean follow-up period was 21±12days (range 2 to 52 days). While transthoracic echocardiography was sufficient to detect vegetations in 69patients (71.9%), IE lesions could be demonstrated bytransesophageal echocardiography in 27 patients (28.1%).The most common involvement was seen in the mitralvalve (54.2%), and the incidence of native valve involvement (79.2%) was greater than that of prosthetic valveinvolvement. Forty-nine patients (51%) were submittedto surgery. In-hospital mortality occurred in 12 patients(12.5%). The prevalence of IE among all patients hospitalized in cardiology department was 0.13%. The culpritmicroorganism was isolated in only 36 patients (37.5%),being staphylococci (33.3%), enterococci (27.8%), brucellae (22.2%), and streptococci (11.1%). Conclusion: The diagnosis and treatment of IE shouldbe designed taking into consideration that epidemiologic and clinical features of IE may differ from those ofindividual countries.

Özet

Amaç: Enfektif endokarditli (EE) olguların klinik ve laboratuvar özellikleri değerlendirildi. Ça­lış­ma pla­nı: Kliniğimizde beş yıllık süre içinde (Ocak 2002-Aralık 2006) 96 hasta (56 erkek, 40 kadın; ort. yaş 47±15; dağılım 16-81) EE tanısıyla tedavi edildi ve izlendi. Tüm hastalar transtorasik ekokardiyografi ve transözofageal ekokardiyografi ile değerlendirildi. Hastaların klinik özellikleri, laboratuvar bulguları belirlendi. Protez kapak endokarditlerinin tümü geç dönem EE idi. Kültürler aerob ve anaerob ortamlara ekilerek 21 güne kadar inkübasyon sağlandı. Enfektif endokardit tanısı Duke ölçütlerine göre kondu. Bul­gu­lar: Erkek/kadın oranı 1.4 bulundu. Başvuru sırasında en sık yakınma (n=58, %60.4) nefes darlığı idi; bunu ateş (n=20, %20.8) ve halsizlik (n=16, %16.7) izlemekteydi. Ortalama izlem süresi 21±12 gün (dağılım 2-52 gün) idi. Transtorasik ekokardiyografi 69 hastada (%71.9) vejetasyon saptanmasında yeterli olurken, EE’ye ait kitle lezyonları 27 hastada (%28.1) transözofageal ekokardiyografi ile saptanabildi. En sık mitral kapak tutulumu (%54.2) izlendi; doğal kapak tutulumu (%79.2) protez kapak tutulumundan fazlaydı. Kırk dokuz hastada (%51) cerrahi endikasyonu kondu. Hastane içi mortalite 12 hastada (%12.5) görüldü. Enfektif endokardit tanısı konan hastaların kardiyoloji servislerine yatan tüm hastalara oranı %0.13 bulundu. Hastaların yalnızca 36’sında (%37.5) sorumlu mikroorganizma kültürde gösterilebildi. En sık etken stafilokoklar (%33.3) idi, bunu enterokoklar (%27.8), brusella (%22.2) ve streptokoklar (%11.1) izlemekteydi. So­nuç: Enfektif endokarditin tanı ve tedavisinin planlanmasında, ülkemizdeki epidemiyolojik ve klinik verilerin diğer ülkelerdekinden farklılıklar gösterdiği dikkate alınmalıdır.

🔖

Cite This Article

ÇAY, S., GÜREL, Ö. M., KORKMAZ, Ş. (2022). Clinical and epidemiological characteristics of infective endocarditis. Türk Kardiyoloji Derneği Arşivi, Cilt: 37 - Sayı: 3, 182–186. https://ajindex.com/articles/633440

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (15)

  1. Fink AM. Endocarditis after valve replacement surgery. Early recognition and treatment are essential to averting deadly complications. Am J Nurs 2006;106:40-51
  2. Hogevik H, Olaison L, Andersson R, Lindberg J, Alestig K. Epidemiologic aspects of infective endocarditis in an urban population. A 5-year prospective study. Medicine 1995;74:324-39
  3. Devlin RK, Andrews MM, von Reyn CF. Recent trends in infective endocarditis: influence of case definitions. Curr Opin Cardiol 2004;19:134-9
  4. Mouly S, Ruimy R, Launay O, Arnoult F, Brochet E, Trouillet JL, et al. The changing clinical aspects of infective endocarditis: descriptive review of 90 episodes in a French teaching hospital and risk factors for death. J Infect 2002;45:246-56
  5. Mylonakis E, Calderwood SB. Infective endocarditis in adults. N Engl J Med 2001;345:1318-30
  6. Berlin JA, Abrutyn E, Strom BL, Kinman JL, Levison ME, Korzeniowski OM, et al. Incidence of infective endocarditis in the Delaware Valley, 1988-1990. Am J Cardiol 1995;76:933-6
  7. Delahaye F, Goulet V, Lacassin F, Ecochard R, Selton-Suty C, Hoen B, et al. Characteristics of infective endocarditis in France in 1991. A 1-year survey. Eur Heart J 1995;16:394-401
  8. Hoen B, Alla F, Selton-Suty C, Béguinot I, Bouvet A, Briançon S, et al. Changing profile of infective endocarditis: results of a 1-year survey in France. JAMA 2002; 288:75-81
  9. Habib G. Management of infective endocarditis. Heart 2006;92:124-30
  10. Moreillon P, Que YA. Infective endocarditis. Lancet 2004;363:139-49
  11. Cabell CH, Jollis JG, Peterson GE, Corey GR, Anderson DJ, Sexton DJ, et al. Changing patient characteristics and the effect on mortality in endocarditis. Arch Intern Med 2002;162:90-4
  12. Fowler VG Jr, Miro JM, Hoen B, Cabell CH, Abrutyn E, Rubinstein E, et al. Staphylococcus aureus endocarditis: a consequence of medical progress. JAMA 2005;293:3012-21
  13. Sohail MR, Martin KR, Wilson WR, Baddour LM, Harmsen WS, Steckelberg JM. Medical versus surgical management of Staphylococcus aureus prosthetic valve endocarditis. Am J Med 2006;119:147-54
  14. Durack DT, Lukes AS, Bright DK. New criteria for diagnosis of infective endocarditis: utilization of specific echocardiographic findings. Duke Endocarditis Service. Am J Med 1994;96:200-9
  15. Baddour LM, Wilson WR, Bayer AS, Fowler VG Jr, Bolger AF, Levison ME, et al. Infective endocarditis: diagnosis, antimicrobial therapy, and management of complications: a statement for healthcare professionals from the C