Journals / Türk Kardiyoloji Derneği Arşivi / 2012 / Cilt: 40 - Sayı: 1

eGFR ve hemoglobin çarpımı, ciddi anemi ve böbrek yetersizliği olmaksızın sistolik kalp yetersizliği olan hastalarda mortaliteyi öngörmede yardımcı olabilir

The product of eGFR and hemoglobin may help predict mortality in systolic heart failure patients without severe anemia and renal failure

Pages
9–15
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Eighty-two patients (55.4%) had an eGFR of

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: Cardiorenal anemia syndrome is defined in patients with heart failure (HF).
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Key Findings & Data:We aimed to investigate whether product of estimated glo- merular filtration rate (eGFR) and hemoglobin (Hb) pre- dicts outcomes in patients with HF.Study design: The study included 148 consecutive pa- tients (89 males, 59 females; mean age 68±10 years) who were hospitalized with acutely decompensated systolic HF and discharged alive.
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Conclusion & Impact:Eighty-two patients (55.4%) had an eGFR of
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: Cardiorenal anemia syndrome is defined in patients with heart failure (HF). Although individual influ- ences of renal impairment and anemia were shown pre- viously, complex interaction between the kidney, bone marrow, and the heart renders decision making relatively inefficient in patients with milder forms of these diseases. We aimed to investigate whether product of estimated glo- merular filtration rate (eGFR) and hemoglobin (Hb) pre- dicts outcomes in patients with HF.Study design: The study included 148 consecutive pa- tients (89 males, 59 females; mean age 68±10 years) who were hospitalized with acutely decompensated systolic HF and discharged alive. Discharge Hb levels were measured. Renal function was estimated via the MDRD (Modification of Diet in Renal Disease) formula. The eGFR x Hb product was derived, and cut-off was defined using the ROC (re- ceiver operating characteristic) analysis. The influence of eGFR x Hb product on mortality was analyzed after a fol- low-up period of up to 34 months (mean 8.2±5.5 months).Results: The mean Hb was 12.7±2 g/dl, the mean creati- nine was 105±46 μmol/l, and the mean eGFR was 61±23 ml/min/1.73 m2. Eighty-two patients (55.4%) had an eGFR of

Özet

Amaç: Kardiyorenal anemi sendromu kalp yetersizliği (KY) hastalarında tanımlanmıştır. Renal bozukluğun ve aneminin ayrı ayrı etkileri daha önce ortaya konmuş olsa da, böbrek, kemik iliği ve kalp arasındaki karmaşık etkileşim, hastalığı daha hafif olan kişilerde karar verme işlemini nispeten verimsiz kılar. Bu çalışmada, tahmini glomerül filtrasyon hızı (eGFR) ve hemoglobin (Hb) çarpımının KY hastalarında sonlanımı öngörmedeki rolünü araştırmayı amaçladık. Çalışma planı: Çalışmaya, akut dekompanse sistolik KY tanısıyla hastaneye yatırılıp taburcu edilen ardışık 148 hasta (89 erkek, 59 kadın; ort. yaş 68±10) alındı. Taburcu edilirken Hb düzeyleri ölçüldü, böbrek fonksiyonu MDRD (Modification of Diet in Renal Disease) formülü ile belirlendi. eGFRxHb çarpımı hesaplanarak, ROC (alıcı işletim karakteristiği) analiziyle kesim değeri çıkarıldı. Hastaların 34 aya varan takipleri (ort. 8.2±5.5 ay) sonrasında eGFRxHb çarpımı değerinin ölüm üzerindeki etkisi araştırıldı. Bulgular: Hasta grubunda ortalama Hb 12.7±2 gr/dl, ortalama kreatinin 105±46 μmol/l ve ortalama eGFR 61±23 ml/dk/1.73 m2 bulundu. Seksen iki hastada (%55.4) eGFR

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Cite This Article

TANDOĞAN, İ., BEKTAŞOĞLU, G., ZORLU, A., YILMAZ, M. B., YONTAR, O. C. (2022). eGFR ve hemoglobin çarpımı, ciddi anemi ve böbrek yetersizliği olmaksızın sistolik kalp yetersizliği olan hastalarda mortaliteyi öngörmede yardımcı olabilir. Türk Kardiyoloji Derneği Arşivi, Cilt: 40 - Sayı: 1, 9–15. https://ajindex.com/articles/633098

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