Journals / Türk Kardiyoloji Derneği Arşivi / 2012 / Cilt: 40 - Sayı: 5

A retrospective investigation of clinical and laboratory findings in children with acute rheumatic fever, reactivation and compliance with prophylaxis)

Akut romatizmal ateşli çocuklarda klinik ve laboratuvar bulguların geriye dönük olarak incelenmesi: Reaktivasyon ve koruyucu tedaviye uyumunun araştırılması

Pages
427–435
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The importance of appropriate prophylaxis should also be emphasized.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: We aimed to retrospectively investigate the patients with acute rheumatic fever (ARF) by evaluating their clinic and laboratory properties, echocardiographic findings as well as the reactivation and the compliance to penicillin prophylaxis.
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Key Findings & Data:Study design: The study involved 255 patients (143 boys, 112 girls; mean age 10.1±2.7 years) with ARF.
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Conclusion & Impact:The importance of appropriate prophylaxis should also be emphasized.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: We aimed to retrospectively investigate the patients with acute rheumatic fever (ARF) by evaluating their clinic and laboratory properties, echocardiographic findings as well as the reactivation and the compliance to penicillin prophylaxis. Study design: The study involved 255 patients (143 boys, 112 girls; mean age 10.1±2.7 years) with ARF. Their sex, age, clinic and laboratory properties, echocardiographic findings, the reactivation and the compliance to penicillin prophylaxis were recorded.Results: Patients spent 13.3±4.3 days in the hospital, and 94 had a history of ARF. Arthritis was found in 233 patients, carditis in 166, Sydenham’s chorea in 14, subcutaneous nodule in 2, and arthritis-carditis in 151 patients. Erythema marjinatum was not found in any patient. Arthralgia (n=15) and fever (n=246) were found in patients. Throat culture was positive in 94 patients and anti-streptolysin-O titers were high in 124 patients. Mitral involvement was found in 205 patients while the combination of mitral and aortic valve involvement were observed in 118 patients.Conclusion: ARF still continues to be a major public health problem in our country. A bad prognosis may be prevented by early diagnosis and treatment. The importance of appropriate prophylaxis should also be emphasized.

Özet

Amaç: Bu çalışmada, akut romatizmal ateşli (ARA) hastaların klinik ve laboratuvar özellikleri, ekokardiyografik bulguları geriye dönük olarak incelendi, reaktivasyon ve penisilin koruyucu tedavi uyumu araştırıldı.Çalışma planı: ARA tanısı alan 255 hastanın (143 erkek, 112 kız; ort. yaş 10.1±2.7 yıl), cinsiyet, yaş, klinik ve laboratuvar özellikleri, ekokardiyografik bulguları yanı sıra reaktivasyonu ve penisilin koruyucu tedavisine uyumları incelendi.Bulgular: Çalışmaya alınan hastaların hastanede kalma süreleri 13.3±4.3 gün idi. ARA öyküsü olan hasta sayısı 94 idi. Majör bulgular, hastaların 233’ünde artrit, 166’sında kardit, 14’ünde Sydenham koresi ve 2’sinde subkütan nodüldü. Artrit ve kardit birlikteliği 151 hastada görüldü, hiçbir hastada eritema marjinatum görülmedi. Minör bulgular ateş (n=246) ve artralji idi (n=15). Hastaların 94’ünde boğaz kültürü pozitifti, antistreptolizin-O 124 hastada yüksek bulundu. İzole mitral kapak tutulumu 205 hastada saptandı, hem mitral hem de aort tutulumu 118 hastada görüldü.Sonuç: ARA ülkemizde önemli bir halk sağlığı sorunu olmaya devam etmektedir. Kötü prognozun önlenmesi için erken tanı ve tedavinin yanı sıra uygun koruyucu tedavinin önemi de vurgulanmalıdır.

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Cite This Article

ŞEN, V., TAŞ, M. A., KANĞIN, M., FİDAN, M., TAŞKESEN, M., MERMUTOĞLU, N., ALYAN, Ö., GÖZÜ, A. P. (2022). A retrospective investigation of clinical and laboratory findings in children with acute rheumatic fever, reactivation and compliance with prophylaxis). Türk Kardiyoloji Derneği Arşivi, Cilt: 40 - Sayı: 5, 427–435. https://ajindex.com/articles/633072

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