Journals / Türk Kardiyoloji Derneği Arşivi / 2012 / Cilt: 40 - Sayı: 3

Alterations in pulmonary artery pressure following mitral valve replacement

Mitral kapak değişimi sonrası pulmoner arter basıncındaki değişiklikler

Pages
235–241
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

It seems that moderate PAP levels do not have a negative influence on postoperative outcomes.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: We sought to evaluate the early postoperative hemodynamics and clinical aspects in patients with moder- ate to severe pulmonary artery pressure (PAP) who under- went mitral valve replacement (MVR) due to isolated mitral valve stenosis.
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Key Findings & Data:Study design: Fifty patients (33 women, 17 men; mean age 45.8±11.2) were divided into two groups according to mean PAP levels (PAP 50 mmHg as Group II).
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Conclusion & Impact:It seems that moderate PAP levels do not have a negative influence on postoperative outcomes.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: We sought to evaluate the early postoperative hemodynamics and clinical aspects in patients with moder- ate to severe pulmonary artery pressure (PAP) who under- went mitral valve replacement (MVR) due to isolated mitral valve stenosis. Study design: Fifty patients (33 women, 17 men; mean age 45.8±11.2) were divided into two groups according to mean PAP levels (PAP 50 mmHg as Group II). PAP and pulmonary capillary wedge pressure PCWP) values were recorded using Swan-Ganz catheter ust before the surgery in the operation theatre. These mea- surements were repeated after weaning from cardiopulmo- nary bypass, at 1, 12 and 24 hours. Intubation period in the ntensive care unit, need for inotropic agents in the pre-and postoperative course, and mortality and morbidity data were also evaluated. Transthoracic echocardiography was used o measure PAP at the postoperative 24th hour and at the 2nd month after the surgery. Results: Mean PAP decreased significantly in both groups compared with basal levels. The regression was higher in Group II than Group I. Decrease in PCWP was more sig- nificant in Group II. PAP had decreased similarly in both groups according to the postoperative 24th hour echocar- diographic evaluation; however, at the postoperative second month follow-up, the decrease in PAP was more significant n Group II. Conclusion: Pulmonary arterial and left atrial pressures significantly decreased in the early periods when the ste- nosis was alleviated in the isolated mitral stenosis cases with moderate or high PAP levels. This study demonstrates he increased morbidity in patients with higher PAP levels undergoing surgery. It seems that moderate PAP levels do not have a negative influence on postoperative outcomes.

Özet

Amaç: İzole mitral kapak darlığı nedeniyle mitral kapak değişimi (MKD) yapılan, orta ve yüksek pulmoner arter basınçlı (PAB) hastalarda ameliyat sonrası erken hemodinami ve klinik özellikler incelendi. Çalışma planı: Elli hasta (33 kadın, 17 erkek; ort. yaş 45.8±11.2) PAB seviyeleri ortalamasına göre iki gruba ayrıldı (Grup 1: PAB 50 mmHg). Tanı aşamasında ve uygulama öncesi ölçülen PAB ve pulmoner kapiller tıkalı basıncı (PCWP) değerleri kaydedildi. Ameliyathanede Swan-Ganz kateteri ile ameliyat öncesi PAB ve PCWP değerleri ölçüldü. Bu ölçümler kardiyopulmoner baypas çıkışında ameliyat sonrası 1., 12. ve 24. saatte tekrarlandı. Ayrıca, olguların yoğun bakımdaki entübasyon süreleri, ameliyat öncesi ve sonrası inotropik ajan, morbidite ve mortalite verileri de değerlendirildi. Ameliyat sonrası 24. saatte ve 2. ayda transtorasik ekokardiyografi ile PAB ölçümü yapıldı. Bulgular: Ortalama PABde her iki grupta da bazal değerlere göre anlamlı derecede düşüş saptandı. Grup 2deki düşüş Grup 1den daha fazla idi. Grup 2nin PCWP değerlerindeki düşüş Grup Iden daha fazla idi. Ameliyat sonrası 24. saatteki ekokardiyografik ölçümlerde her iki grupta da PABde anlamlı derecede düşüşler görülürken, 2. aydaki ölçümlerde Grup 2deki PAB değerleri Grup 1e göre daha fazla düşüş gösterdi. Sonuç: Yüksek ve orta derecedeki pulmoner arter basınçlı izole mitral darlığı olgularında, engel ortadan kalktığında pulmoner arter ve sol atriyal basınçlarda erken dönemde dahi anlamlı düşüşler saptanmıştır. Çalışmamız, cerrahiye giden yüksek PABli olgularda morbiditenin yüksek olduğunü göstermiştir, orta derecedeki PAB yüksekliği olan hastalarda ameliyat sonrası sonuçlarda olumsuz bir etki görülmemiştir.

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Cite This Article

TAŞOĞLU, İ., LAFÇI, G., KORKMAZ, K., GEDİK, H. S., ALTINTAŞ, G., ÇAĞLI, K., ÖZCAN, F., DİKEN, A. İ. (2022). Alterations in pulmonary artery pressure following mitral valve replacement. Türk Kardiyoloji Derneği Arşivi, Cilt: 40 - Sayı: 3, 235–241. https://ajindex.com/articles/633051

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