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Journals / Türk Kardiyoloji Derneği Arşivi / 2012 / Cilt: 40 - Sayı: 7

Klasik aterosklerotik risk faktörü bulunmayan plak tipi psoriasisi olan hastalarda subklinik aterosklerozun değerlendirilmesi

Determination of subclinical atherosclerosis in plaque type psoriasis patients without traditional risk factors for atherosclerosis

İbrahim BAŞARICI
İbrahim DEMİR
Serkan KOÇ
Emre Refik ALTEKİN
Erkan ALPSOY
Mustafa Serkan KARAKAŞ
Atakan YANIKOĞLU
Pages
574–580
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Results: PWV, and the maximum and average CIMT values of psoriasis patients were higher than those of the healthy group (PWV: 7.04±1.1 m/sn vs. 6.03±0.61 m/sn, p

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: Systemic inflammation plays an important role in the pathogenesis of atherosclerosis in psoriasis patients.
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Key Findings & Data:Study design: Fifty-seven plaque-type psoriasis patients (31 males, 26 females; mean age 41±10.8 years) and 60 healthy individuals (32 males, 28 females; mean age 40±9.4 years) were included.
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Conclusion & Impact:Results: PWV, and the maximum and average CIMT values of psoriasis patients were higher than those of the healthy group (PWV: 7.04±1.1 m/sn vs. 6.03±0.61 m/sn, p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: Systemic inflammation plays an important role in the pathogenesis of atherosclerosis in psoriasis patients. Therefore, persistent skin inflammation in psoriasis patients may contribute to the development of premature atherosclerosis, as it occurs in rheumatoid arthritis and systemic lupus erythematosus. We aimed to evaluate the relationship between subclinical atherosclerosis and psoriasis by using pulse wave velocity (PWV) and the measurement of carotid intima media thickness (CIMT) in psoriatic patients. Study design: Fifty-seven plaque-type psoriasis patients (31 males, 26 females; mean age 41±10.8 years) and 60 healthy individuals (32 males, 28 females; mean age 40±9.4 years) were included. Atherosclerotic risk factors were excluded in both of the groups. Demographic, bio-chemical data, psoriasis area and severity index (PASI) score of the psoriasis group, and disease duration were recorded. Carotid- femoral artery PWV and CIMT values were compared. Results: PWV, and the maximum and average CIMT values of psoriasis patients were higher than those of the healthy group (PWV: 7.04±1.1 m/sn vs. 6.03±0.61 m/sn, p

Özet

Amaç: Psoriasisli hastalarda görülen sistemik enflamasyon ateroskleroz gelişiminde önemli rol oynayabilir. Bu hastalarda görülen kronik enflamasyon, romatoid artrit ve sistemik lupus eritamozuslu hastalarda olduğu gibi erken ateroskleroz gelişimine katkıda bulunabilir. Çalışmamızda, nabız dalga hızı (NDH) ve karotis intima medya kalınlığı (KİMK) ölçüm yöntemleri kullanarak, psoriasis ile subklinik ateroskleroz arasındaki ilişkinin araştırılması amaçlandı. Çalışma planı: Klasik ateroskleroz risk faktörleri bulunmayan, plak tipi psoriasisi olan 57 hasta (31 erkek, 26 kadın; ort. yaş 41±10.8 yıl) ve 60 sağlıklı birey (32 erkek, 28 kadın; ort. yaş. 40±9.4 yıl) çalışmaya alındı. Çalışmaya alınan bireylerin demografik, biyokimyasal verilerine ek olarak, hastalıklı bireylerde psoriasis alanını ve ciddiyet indeksini ölçen PASİ skoru ve hastalığın süresi kayıt edildi. Sağlıklı ve psoriasisli olgularda karotis ve femoral arterlerde yapılan NDH ve KİMK ölçümleri karşılaştırıldı. Bulgular: NDH, maksimal ve ortalama KİMK değerleri psoriasis grubunda, sağlıklı gruptan fazla bulundu (sırasıyla, NDH: 7.04±1.1 m/sn ve 6.03±0.61 m/sn, p

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Cite This Article

BAŞARICI, İ., DEMİR, İ., KOÇ, S., ALTEKİN, E. R., ALPSOY, E., KARAKAŞ, M. S., YANIKOĞLU, A. (2022). Klasik aterosklerotik risk faktörü bulunmayan plak tipi psoriasisi olan hastalarda subklinik aterosklerozun değerlendirilmesi. Türk Kardiyoloji Derneği Arşivi, Cilt: 40 - Sayı: 7, 574–580. https://ajindex.com/articles/632983

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