Journals / Türk Kardiyoloji Derneği Arşivi / 2013 / Cilt: 41 - Sayı: 7

Koroner arter ektazisi ile ortalama trombosit hacmi, gama glutamil transferaz ve ürik asit düzeyleri arasında anlamlı ilişki yoktur

No relevant association between coronary artery ectasia and mean platelet volume, gamma-glutamyltransferase and uric acid levels

Pages
598–603
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Unlike previous studies, our study failed to dem- onstrate any association between CAE and MPV, uric acid and GGT levels.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: In this study, we aimed to investigate whether there is an association between mean platelet volume (MPV), gamma-glutamyltransferase (GGT) and uric acid and coro- nary artery ectasia (CAE) in a large patient population.
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Key Findings & Data:Study design: A total of 406 patients (245 male, 161 female; mean age: 55±9 years) were selected retrospectively as the study population from among 3265 individuals who underwent coronary angiography between August 2011 and December 2012.
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Conclusion & Impact:Conclusion: Unlike previous studies, our study failed to dem- onstrate any association between CAE and MPV, uric acid and GGT levels.
🔬Design:Research Article
📍Scope:2011 Verileri
⚙️Variables:Domain Parameters

Abstract

Objectives: In this study, we aimed to investigate whether there is an association between mean platelet volume (MPV), gamma-glutamyltransferase (GGT) and uric acid and coro- nary artery ectasia (CAE) in a large patient population. Study design: A total of 406 patients (245 male, 161 female; mean age: 55±9 years) were selected retrospectively as the study population from among 3265 individuals who underwent coronary angiography between August 2011 and December 2012. Information regarding blood tests of the patients ob- tained during hospitalization was extracted from the institute electronic database. Results: MPV, GGT and uric acid levels were significantly higher in subjects with stenotic coronary artery disease (CAD) and in subjects with both CAD and CAE compared with sub- jects with isolated CAE and subjects with normal coronary ar- teries (NCA). There were no significant differences between the isolated CAE and NCA groups in terms of MPV (8.6±1.2 fL vs. 8.6±1.1, respectively, p=0.993), serum GGT (33±15 U/L vs. 30±15 U/L, respectively, p=0.723) and uric acid levels (5.4±1.6 mg/dl vs. 5.2±1.7 mg/dl, respectively, p=0.845). Conclusion: Unlike previous studies, our study failed to dem- onstrate any association between CAE and MPV, uric acid and GGT levels.

Özet

Amaç: Bu çalışmada büyük bir hasta grubunda, ortalama trombosit hacmi (OTH), gama glutamil transferaz (GGT) ve ürik asit (ÜA) düzeylerinin koroner arter ektazisi ile ilişkilerini araştırmayı amaçladık.Çalışma planı: Çalışma grubunu oluşturan 406 hasta (245 erkek, 161 kadın, ortalama yaş 55±9 yıl), Ağustos 2011 ve Aralık 2012 tarihleri arasında koroner anjiyografi yapılmış olan 3265 hasta içerisinden geriye dönük olarak seçildi. Hastaneye yatış esnasında alınan kan testlerini içeren bilgi hastane elektronik veritabanından çıkarıldı.Bulgular: OTH, GGT ve ürik asit düzeyleri, hem tek başına hem de koroner arter ektazisi ile birlikte ciddi koroner darlığı bulunan hastalarda izole koroner ektazisi bulunanlara göre anlamlı olarak yüksekti. Ancak, izole koroner ektazisi bulunanlar ile normal koroner arter tespit edilenler arasında OTH (8.6±1.2 fLe karşı 8.6±1.1, p=0.993), GGT (33±15 U/Le karşı 30±15 U/L, p=0.723) ve ürik asit düzeyleri (5.4±1.6 mg/dle karşı 5.2±1.7 mg/dl, p=0.845) açısında anlamlı fark yoktu.Sonuç: Bu çalışmada, önceki çalışmaların aksine koroner arter ektazisi ile OTH, GGT ve ürik asit düzeyleri arasında ilişki bulunmamıştır.

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Cite This Article

SAĞLAM, H., KARADAĞ, Z., ŞARLI, B., BAKTIR, A. O., KATLANDUR, H., ARINÇ, H., KAYA, M. G., AKPEK, M., KURTUL, S. (2022). Koroner arter ektazisi ile ortalama trombosit hacmi, gama glutamil transferaz ve ürik asit düzeyleri arasında anlamlı ilişki yoktur. Türk Kardiyoloji Derneği Arşivi, Cilt: 41 - Sayı: 7, 598–603. https://ajindex.com/articles/632968

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