Journals / Türk Kardiyoloji Derneği Arşivi / 2013 / Cilt: 41 - Sayı: 5

Akut koroner sendromlu hastalarda yüksek eritrosit dağılım genişliği koroner kollaterallerin yokluğu ile ilişkilidir

Increased red cell distribution width level is associated with absence of coronary collateral vessels in patients with acute coronary syndromes

Pages
399–405
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: We found that high levels of RDW were associ- ated with absence of CCV in patients with ACS.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objectives: Several studies have evaluated a relationship between increased red cell distribution width (RDW) and mor- bidity and mortality of acute coronary syndrome (ACS).
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Key Findings & Data:Study design: We evaluated 226 patients with ACS in this pro- spective and cross-sectional study.
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Conclusion & Impact:Conclusion: We found that high levels of RDW were associ- ated with absence of CCV in patients with ACS.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: Several studies have evaluated a relationship between increased red cell distribution width (RDW) and mor- bidity and mortality of acute coronary syndrome (ACS). In this study, we aimed to investigate the association of serum RDW levels and development of coronary collateral vessel (CCV) in patients with ACS. Study design: We evaluated 226 patients with ACS in this pro- spective and cross-sectional study. Traditional laboratory and clinical parameters and serum RDW levels were measured on admission. All patients underwent coronary angiography on the first day after admission and patients with >80% stenosis were included in the study. The CCV was graded according to the Rentrop scoring system, and a Rentrop grade 0 was accepted as no CCV development (Group 1), while Rentrop grades 1-2-3 were accepted as presence of CCV development (Group 2). Results: Only levels of RDW were significantly higher in Group 1 than in Group 2 (Group 1 RDW 14.6±1.9, Group 2 RDW 14.1±1.4, p=0.02). The predictive value of serum RDW level for absence of collaterals (sensitivity of 58% and speci- ficity of 54%, area under the receiver operating characteristic (ROC) curve = 0.573) was 13.90. Conclusion: We found that high levels of RDW were associ- ated with absence of CCV in patients with ACS.

Özet

Amaç: Eritrosit dağılım genişliği (EDG) ile akut koroner sendromların (AKS) morbidite ve mortalitesi arasındaki ilişki çeşitli çalışmalarda araştırılmıştır. Bu çalışmada, AKSli hastalarda EDG ile koroner kollateral damar (KKD) gelişimi arasındaki ilişki araştırıldı.Çalışma planı: Çalışmada AKSli 226 hasta ileriye dönük ve kesitsel olarak incelendi. Geleneksel laboratuvar ve klinik parametreler ve EDG düzeyleri hasta kabul edilirken ölçüldü. Tüm hastalara kabulden sonraki birinci gün içinde koroner anjiyografi yapıldı ve %80 ve üzerinde damar tıkanıklığı olan hastalar çalışmaya alındı. Koroner kollateral damar dereceleri Rentrop skoruna göre değerlendirildi ve Rentrop 0 KKD olmayan grup (Grup 1), Rentrop 1, 2, 3 KKD olan grup (Grup 2) olarak kabul edildi. Bulgular: Grup 1de sadece EDG Grup 2ye göre anlamlı derecede yüksekti (Grup 1 EDG 14.6±1.9, Grup 2 EDG 14.1±1.4, p=0.02). Koroner kollateral damar yokluğunu öngördüren EDG değeri (%58 duyarlılık ve 54 özgüllük ile, ROC [receiver-operating characteristics] eğrisi altındaki alan =0.573) 13.90 idi. Sonuç: Akut koroner sendromlu hastalarda yüksek EDG düzeylerinin KKD yokluğu ile ilişkili olduğunu bulduk.

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Cite This Article

AKIN, F., OĞUZHAN, A., DURAN, M., ERYOL, N. K., YILMAZ, Y., BARAN, O., ERGİN, A., KAYA, M. G., GÜNEBAKMAZ, Ö., İNANÇ, M. T., UYSAL, O. K. (2022). Akut koroner sendromlu hastalarda yüksek eritrosit dağılım genişliği koroner kollaterallerin yokluğu ile ilişkilidir. Türk Kardiyoloji Derneği Arşivi, Cilt: 41 - Sayı: 5, 399–405. https://ajindex.com/articles/632967

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