Evaluation of subclinical atherosclerosis in chronic sinusitis patients

Objective & Hypothesis:Objective: This study aimed to assess the impact of chronic sinusitis (CS) on carotid-intima-media thickness (CIMT), a marker of early atherosclerotic changes in the arterial bed.

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Key Findings & Data:Methods: The study included 50 patients with CS (25 male, 25 female, mean age 26.6±5.34 years), and 50 healthy subjects (25 male, 25 female, mean age 25.8±4.76 years), aged 18 to 35 years without atherosclerotic risk factors, normal body mass index and normal metabolic parameters.

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Conclusion & Impact:However, mean values of CIMT (mm) were significantly greater in CS patients than in healthy subjects (0.51±0.09 vs. 0.40±0.07, p

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Domain Parameters

Abstract

Objective: This study aimed to assess the impact of chronic sinusitis (CS) on carotid-intima-media thickness (CIMT), a marker of early atherosclerotic changes in the arterial bed. Methods: The study included 50 patients with CS (25 male, 25 female, mean age 26.6±5.34 years), and 50 healthy subjects (25 male, 25 female, mean age 25.8±4.76 years), aged 18 to 35 years without atherosclerotic risk factors, normal body mass index and normal metabolic parameters. CIMT was measured in all patients by ultrasonography. CS was confirmed by medical history and computed tomography scan of the paranasal cavities. Results: No significant difference existed between the groups in terms of age, sex, body mass index (BMI), waist circumference, plasma creatinine, glucose, low-density lipoprotein (LDL), highdensity lipoprotein (HDL) cholesterol values (p>0.05). However, mean values of CIMT (mm) were significantly greater in CS patients than in healthy subjects (0.51±0.09 vs. 0.40±0.07, p

Özet

Amaç: Bu çalışmada, kronik sinüzitin (KS) arter sistemindeki erken dönem aterosklerotik değişikliklerin bir göstergesi olan karotis intima-medya kalınlığı (KİMK) üzerindeki etkisini değerlendirmeyi amaçladık.Yöntemler: Aterosklerotik risk faktörleri olmayan, normal beden kütle indeksi (BKİ) ve normal metabolik parametreleri olan 18-35 yaş arasında KSli 50 hasta (25 erkek, 25 kadın, ort. yaş 26.6±5.34 yıl) ve 50 sağlıklı birey (25 erkek, 25 kadın, ort. yaş 25.8±4.76 yıl) çalışmaya dahil edildi. Tüm hastalarda, KİMK ultrason aracılığıyla ölçüldü. Kronik sinüzit, tıbbi öykü ve paranazal boşlukların bilgisayarlı tomografi taraması aracılığıyla doğrulandı.Bulgular: Gruplar arasında yaş, cinsiyet, BKİ, bel çevresi, serum kreatinin, glukoz, düşük yoğunluklu lipoprotein (LDL) ve yüksek yoğunluklu lipoprotein (HDL) kolesterol değerleri açısından önemli farklılık yoktu (p>0.05). Ancak, ortalama KİMK (mm) KSli hastalarda sağlıklı bireylerden önemli derecede fazlaydı (0.51±0.09 ve 0.40±0.07, p

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Cite This Article

KARATAŞ, M., DOĞAN, S., SARIKAYA, Y., DOĞAN, A., ÇAKICI, M., KASKALAN, E., ABUŞ, S., ÇETİN, M., POLAT, M., TAŞOLAR, H. (2022). Evaluation of subclinical atherosclerosis in chronic sinusitis patients. Türk Kardiyoloji Derneği Arşivi, Cilt: 43 - Sayı: 3, 234–241. https://ajindex.com/articles/632651

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