Journals / Türk Kardiyoloji Derneği Arşivi / 2016 / Cilt: 44 - Sayı: 4

Hipertrfik kardiyomiyopatili bir hastada sol ventriküldeki trombüsün apiksaban tedavisi ile rezolüsyonu

Resolution of left ventricular thrombus with apixaban in a patient with hypertrophic cardiomyopathy

Pages
335–337
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

To the best of our knowl-edge, this is the first report that describes the resolution of LV thrombus with apixaban treatment in a patient with hy-pertrophic cardiomyopathy.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Summary- Anticoagulation with warfarin is the main treat-ment of intracardiac thrombus.
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Key Findings & Data:The case of a 60-year-old woman with left ventricular (LV) thrombus sec-ondary to hypertrophic cardiomyopathy and AF is described in the present report.
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Conclusion & Impact:To the best of our knowl-edge, this is the first report that describes the resolution of LV thrombus with apixaban treatment in a patient with hy-pertrophic cardiomyopathy.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Summary- Anticoagulation with warfarin is the main treat-ment of intracardiac thrombus. While novel oral anticoagu-lants (NOACs) have been approved by the US Food and Drug Administration (FDA) for stroke prevention in patients with nonvalvular atrial fibrillation (AF), they are not indicat-ed for resolution of intracardiac thrombus. The case of a 60-year-old woman with left ventricular (LV) thrombus sec-ondary to hypertrophic cardiomyopathy and AF is described in the present report. Indications for oral anticoagulation were AF and LV thrombus. Thrombus was dissolved after 1 month of apixaban treatment. To the best of our knowl-edge, this is the first report that describes the resolution of LV thrombus with apixaban treatment in a patient with hy-pertrophic cardiomyopathy.

Özet

Kalp içi trombüsü olan hastalarda ana tedavi var-farin ile antikoagülasyondur. Bu ilaçlar kapak hastalığı ol-mayan atriyum fibrilasyonlu hastalarda inmeden korumada Amerikan Gıda ve İlaç İdaresi (FDA) tarafından onaylan-mıştır, fakat hiçbirinin kalp içi trombüs rezolüsyonunda en-dikasyonu yoktur. Bu yazıda, hipertrofik kardiyomyopati ve atriyum fibrilasyonu tanıları konan ve sol ventrikülde trom-büs gelişen 60 yaşında bir kadın hasta sunuldu. Oral anti-koagülasyon için iki endikasyon mevcuttur; atriyum fibrilas-yonu ve ventrikül trombüsü. Trombüs bir aylık apiksaban tedavisinden sonra kayboldu. Bu olgu bildiğimiz kadarıyla sol ventrikülde trombüsü olan ve apiksaban tedavisiyle kaybolan ilk hipertrofik kardiyomiyopatili olgudur.

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Cite This Article

TEKKEŞİN, A. İ., HAYIROĞLU, M. İ., KESKİN, M., KAYA, A., ALPER, A. T. (2022). Hipertrfik kardiyomiyopatili bir hastada sol ventriküldeki trombüsün apiksaban tedavisi ile rezolüsyonu. Türk Kardiyoloji Derneği Arşivi, Cilt: 44 - Sayı: 4, 335–337. https://ajindex.com/articles/632617

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References (3)

  1. Griffin BP. Manual of cardiovascular medicine. 4th ed. Phila- delphia, PA: Lippincott Williams and Wilkins; 2013. Kaku B. Intra-cardiac thrombus resolution after anti-coagula- tion therapy with dabigatran in a patient with mid-ventricular obstructive hypertrophic cardiomyopathy: a case report. J Med Case Rep 2013;7:238. Wolf PA, Abbott RD, Kannel WB. Atrial fibrillation as an independent risk factor for stroke: the Framingham Study. Stroke 1991;22:983-8.
  2. Go AS, Hylek EM, Phillips KA, Chang Y, Henault LE, Selby JV, et al. Prevalence of diagnosed atrial fibrillation in adults: national implications for rhythm management and stroke pre- vention: the AnTicoagulation and Risk Factors in Atrial Fi- brillation (ATRIA) Study. JAMA 2001;285:2370-5. Yates SW. Novel oral anticoagulants for stroke prevention in atrial fibrillation: a focus on the older patient. Int J Gen Med 2013;6:167-80.
  3. Takasugi J, Yamagami H, Okata T, Toyoda K, Nagatsuka K. Dissolution of the left atrial appendage thrombus with rivar- oxaban therapy. Cerebrovasc Dis 2013;36:322-3.