Journals / Türk Kardiyoloji Derneği Arşivi / 2015 / Cilt: 43 - Sayı: 8

İzole sol ana koroner arter darlığının uzun dönem cerrahi revaskülarizasyon sonuçları: Tek merkezli sağkalım çalışması

Long term outcomes of surgical revascularization for isolated left main coronary artery stenosis: a single-center surveillance study

Pages
684–691
Publication Date
2022-11-05
DOI
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Conclusion: Postoperative short- and long-term prognosis ofisolated LMCA stenosis appears good in terms of mortalityand coronary event symptoms.

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Objective & Hypothesis:Objective: The objective of this study was to retrospectivelyanalyze the clinical course and postoperative long-term sur- vival of patients diagnosed with isolated left main coronaryartery (LMCA) stenosis after surgical revascularization.
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Key Findings & Data:Methods: A total of 38 patients (27 males, 11 females) whowere diagnosed with isolated LMCA stenosis and underwentsurgical revascularization were enrolled in the study.
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Conclusion & Impact:Conclusion: Postoperative short- and long-term prognosis ofisolated LMCA stenosis appears good in terms of mortalityand coronary event symptoms.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: The objective of this study was to retrospectivelyanalyze the clinical course and postoperative long-term sur- vival of patients diagnosed with isolated left main coronaryartery (LMCA) stenosis after surgical revascularization. Methods: A total of 38 patients (27 males, 11 females) whowere diagnosed with isolated LMCA stenosis and underwentsurgical revascularization were enrolled in the study. IsolatedLMCA stenosis was classified into 2 groups: ostial stenosisand nonostial stenosis. Coronary events were defined asdeath of cardiac origin, the need for a new myocardial re- vascularization procedure, or the occurrence of myocardialinfarction in the course of follow-up. The postoperative as- sessment period included short- and long-term follow-up. Thestudy endpoint was defined as all-cause mortality. Results: Among the 38 patients who participated in the study,25 suffered from ostial LMCA stenosis. The early postopera- tive mortality rate before hospital discharge was 2.6%. Me- dian duration of postoperative long-term follow-up was 73.43months (range: 0.17 187.23). Median duration of long-termfollow-up free from coronary events or percutaneous coro- nary interventions was 73.43 months. Postoperative 2-yearsurvival rate was 97.4%, and 5-year survival rate was 92.1%.The postoperative survival period and period free of coronaryevents of patients with isolated ostial LMCA stenosis did notdiffer significantly from those of patients with nonostial steno- sis (p=0.801, p=0.970, respectively). Conclusion: Postoperative short- and long-term prognosis ofisolated LMCA stenosis appears good in terms of mortalityand coronary event symptoms.

Özet

Amaç: Bizim bu çalışmadaki amacımız sol ana koroner arter(LMCA) darlığı olan hastaların cerrahi revaskülarizasyon son- rası klinik seyir ve uzun dönem sağkalım sonuçlarını geriyedönük olarak incelemektir. Yöntemler: Bu çalışmaya tek başına LMCA darlığı tanısıkonulan ve cerrahi revaskülarizasyon yapılan 38 hasta (27erkek, 11 kadın) alındı. Tek başına LMCA darlığı iki grup- ta sınıflandırıldı: Ostial ve nonostial darlık. Takip seyrinde;kalp nedenli ölüm, yeni bir miyokart revaskülarizasyonu ih- tiyacı veya miyokart enfarktüsü gelişimi koroner olay olaraktanımlandı. Ameliyat sonrası değerlendirme periyodu erkenve uzun dönem takiplerinden oluşmaktaydı. Çalışmanınsonlanım noktası tüm nedenlere bağlı ölüm olarak tanım- landı.Bulgular: Çalışmaya katılan 38 hastanın 25inde LMCA os- tial darlığı mevcuttu. Hastaneden taburcu edilmeden öncekierken dönem ameliyat sonrası mortalitesi %2.6 idi. Ameliyatsonrası uzun dönemde medyan takip süresi 73.43 (dağılım,0.17-187.23) aydı. Revaskülarizasyon sonrası koroner olaysız veya perkütan koroner girişimsiz geçen medyan süre73.43 aydı. Ameliyat sonrası iki yıllık sağkalım oranı %97.4;beş yıllık sağkalım oranı %92.1 idi. Ostial ve nonostial darlığı olan hastaların koroner olaysız geçen süreleri ve ameliyatsonrası sağkalım sonuçları arasında anlamlı farklılık yoktu (sırasıyla, p=0.801 ve p=0.970). Sonuç: Mortalite ve koroner olaylar açısından bakıldığı zaman tek başına LMCA darlığının ameliyat sonrası kısa veuzun dönem prognozu iyi gözükmektedir.

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Cite This Article

ALTAY, S., ÖZER, N., VELİBEY, Y., GÜZELBURÇ, Ö., AYKUT, S. A., TUSUN, E., BAKSHALİYEV, N., KARACA, M., YEKELER, İ., EREN, M. (2022). İzole sol ana koroner arter darlığının uzun dönem cerrahi revaskülarizasyon sonuçları: Tek merkezli sağkalım çalışması. Türk Kardiyoloji Derneği Arşivi, Cilt: 43 - Sayı: 8, 684–691. https://ajindex.com/articles/632589

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References (13)

  1. Arima M, Kanoh T, Okazaki S, Iwama Y, Matsuda S, Naka- zato Y. Long-term clinical and angiographic follow-up in pa- tients with isolated ostial stenosis of the left coronary artery. Circ J 2009;73:1271–7
  2. Martinovic I, Greve H. Surgical treatment of the isolated left ostial stenosis. J Cardiovasc Surg (Torino) 2012;53:375–9
  3. Harling L, Sepehripour AH, Ashrafian H, Lane T, Jarral O, Chikwe J, et al. Surgical patch angioplasty of the left main coronary artery. Eur J Cardiothorac Surg 2012;42:719–27
  4. Gan HL, Zhang JQ, Xiao W, Zhao S, Huang FJ, Gu CX, et al. Ostial left main coronary artery stenosis as an additional risk factor in off-pump coronary artery bypass grafting. J Thorac Cardiovasc Surg 2012;143:103–10
  5. Kawakami H, Matsuoka H, Koyama Y, Saeki H, Inoue K, Nishimura K, et al. Isolated left coronary ostial stenosis as a result of fibromuscular dysplasia in a young man. Jpn Circ J 2000;64:988–9
  6. Loop FD, Lytle BW, Cosgrove DM, Sheldon WC, Irarrazaval M, Taylor PC, et al. Atherosclerosis of the left main coronary artery: 5 years results of surgical treatment. Am J Cardiol 1979;44:195–201
  7. Caracciolo EA, Davis KB, Sopko G, Kaiser GC, Corley SD, Schaff H, et al. Comparison of surgical and medical group survival in patients with left main coronary artery disease. Long-term CASS experience. Circulation 1995;91:2325–34
  8. Campeau L, Corbara F, Crochet D, Petitclerc R. Left main coronary artery stenosis: the influence of aortocoronary by- pass surgery on survival. Circulation 1978;57:1111–5. 9. d’Allonnes FR, Corbineau H, Le Breton H, Leclercq C, Le- guerrier A, Daubert C. Isolated left main coronary artery ste- nosis: long term follow up in 106 patients after surgery. Heart 2002;87:544–8
  9. Thompson R. Isolated coronary ostial stenosis in women. J Am Coll Cardiol 1986;7:997–1003
  10. Koh KK, Hwang HK, Kim PG, Lee SH, Cho SK, Kim SS, et al. Isolated left main coronary ostial stenosis in Oriental people: operative, histopathologic and clinical findings in six patients. J Am Coll Cardiol 1993;21:369–73
  11. Darabian S, Amirzadegan AR, Sadeghian H, Sadeghian S, Abbasi A, Raeesi M. Ostial lesions of left main and right coro- nary arteries: demographic and angiographic features. Angiol- ogy 2009;59:682–7
  12. Wilson VE, Bates ER. Subacute bilateral coronary ostial ste- noses following cardiac catheterization and PTCA. Cathet Cardiovasc Diagn 1991;23:114–6
  13. Shin H, Katogi T, Yozu R, Kawada S. Surgical angioplasty of left main coronary sten