Journals / Türk Kardiyoloji Derneği Arşivi / 2016 / Cilt: 44 - Sayı: 3

Yavaş koroner akımla normal-hafif bozulmuş böbrek fonksiyonları arasında bir ilişki var mı?

Is there a relationship between slow coronary flow and normal to mildly impaired renal function?

Pages
207–214
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: No correlation was found between SCF and nor- mal to mildly impaired renal function.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The Chronic Kidney Disease Epidemiology Col- laboration (CKD-EPI) equation is more effective at estimatingglomerular filtration rate (GFR) than the Modification of Dietin Renal Disease (MDRD) equation, particularly in patientswith mildly impaired renal function.
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Key Findings & Data:Recent studies have dem- onstrated, using the Cockroft-Gault and MDRD formulas, asignificant correlation between slow coronary flow (SCF) andnormal to mildly impaired renal function.
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Conclusion & Impact:Conclusion: No correlation was found between SCF and nor- mal to mildly impaired renal function.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: The Chronic Kidney Disease Epidemiology Col- laboration (CKD-EPI) equation is more effective at estimatingglomerular filtration rate (GFR) than the Modification of Dietin Renal Disease (MDRD) equation, particularly in patientswith mildly impaired renal function. Recent studies have dem- onstrated, using the Cockroft-Gault and MDRD formulas, asignificant correlation between slow coronary flow (SCF) andnormal to mildly impaired renal function. However, these stud- ies had some limitations. The aim of the present study was toinvestigate the relationship between SCF and normal to mildlyimpaired renal function using the CKD-EPI equation. Methods: A total of 370 patients were included, 172 with nor- mal coronary flow (NCF) and 198 with SCF. All participantshad normal to mildly impaired renal function. Both the CKD- EPI and MDRD formulas were used to calculated estimatedglomerular filtration rate (eGFR), which was compared be- tween groups. Results: No significant difference in mean values of eGFR wasfound between the NCF and SCF groups (CKD-EPI: 92.9±14.7vs 92.7±14.2, p=0.72; MDRD: 89.5±19.5 vs 88.2±17.0, p=0.70,respectively). Among patients with eGFR(MDRD) ≥90 mL/ min/1.73 m2, mean eGFR levels were lower among patientswith SCF (107.0±12.7 vs 102.7±10.0, p=0.02). Conclusion: No correlation was found between SCF and nor- mal to mildly impaired renal function.

Özet

Amaç: Hafif bozulmuş böbrek fonksiyonları olan hastalardaglomerül filtrasyon hızını (GFR) tahmin etmede CKD-EPI(The Chronic Kidney Disease Epidemiology Collaboration)formülü MDRD (Modification of Diet in Renal Disease) formü- lünden daha etkindir. Yeni yayınlar, MDRD ve Cockroft-Gaultformüllerini kullanarak yavaş koroner akımla (YKA) normal- hafif bozulmuş böbrek fonksiyonları arasında ilişki olduğunugöstermiştir; ancak bu çalışmaların bazı kısıtlılıkları mevcut- tur. Biz, CKD-EPI denklemini kullanarak, YKA ile normal-hafifbozulmuş böbrek fonksiyonları arasındaki ilişkiyi araştırmayıamaçladık. Yöntemler: Çalışmaya 370 hasta alındı (172 hasta normalkoroner akım [NKA], 198 hasta YKA). Böbrek fonksiyonlarınormal-hafif bozulmuş hastalar seçildi. İki gruptaki tüm has- taların tahmini glomerül filtrasyon hızı (eGFR) CKD-EPI veMDRD formülleri ile hesaplandı ve sonuçları karşılaştırıldı. Bulgular: Ortalama değerler bazında NKA ve YKA arasındaeGFR açısından yapılan ölçümlerde anlamlı bir fark yoktu (sı- rasıyla, CKD-EPI: 92.9±14.7 ve 92.7±14.2, p=0.72; MDRD:89.5±19.5 ve 88.2±17.0, p=0.70). Ölçülen eGFR(MDRD) ≥90mL/dk/1.73 m2 alt grup hastalarda ortalama eGFR değerleriaçısından YKA olan hastalarda daha az bulundu (107.0±12.7ve 102.7±10.0, p=0.02). Sonuç: Yavaş koroner akımla normal-hafif bozulmuş böbrekfonksiyonları arasında bir ilişki bulunmadı.

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Cite This Article

ÇABUK, A. K., GÜRAY, Ü., ÇABUK, G., KARAMANLIOĞLU, M., KADER, E. U., BAĞLAN, S. U., ASLANTÜRK, Ö. F. (2022). Yavaş koroner akımla normal-hafif bozulmuş böbrek fonksiyonları arasında bir ilişki var mı?. Türk Kardiyoloji Derneği Arşivi, Cilt: 44 - Sayı: 3, 207–214. https://ajindex.com/articles/632498

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