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Journals / Türk Kardiyoloji Derneği Arşivi / 2017 / Cilt: 45 - Sayı: 8

Primer perkütan koroner girişim ile tedavi edilen ST yükselmeli miyokart enfarktüslü hastalarda stent restenozu ile koroner arter hastalığının yaygınlığı arasındaki ilişkinin değerlendirilmesi

Relationship between the extent of coronary artery disease and in-stent restenosis in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention

Atila İYİSOY
Murat ÇELİK
Uygar Çağdaş YÜKSEL
Cem BARÇIN
Yalçın GÖKOĞLAN
Salim YAŞAR
Suat GÖRMEL
Mustafa KOKLU
Erkan YILDIRIM
Barış BUĞAN
Pages
702–714
Publication Date
2022-11-05
DOI
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⚡ TL;DR(Too Long; Didn't Read)

The mean Gensini score was significantly higher in patients with ISR when compared with group without restenosis (69 [range: 51–90] vs 42 [range: 32–61]; p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The pathophysiological mechanism of in-stent restenosis (ISR) is different from atherosclerosis of native coronary arteries.
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Key Findings & Data:Methods: A total of 372 consecutive patients presenting with first acute STEMI who were successfully treated with primary percutaneous coronary intervention within 12 hours from the onset of symptoms and who had an angiographic follow-up at 3 months were included in the study.
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Conclusion & Impact:The mean Gensini score was significantly higher in patients with ISR when compared with group without restenosis (69 [range: 51–90] vs 42 [range: 32–61]; p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: The pathophysiological mechanism of in-stent restenosis (ISR) is different from atherosclerosis of native coronary arteries. The aim of this study was to evaluate the relationship between ISR and the extent of coronary artery disease (CAD), and to identify other risk factors associated with ISR in ST-segment elevation myocardial infarction (STEMI) patients. Methods: A total of 372 consecutive patients presenting with first acute STEMI who were successfully treated with primary percutaneous coronary intervention within 12 hours from the onset of symptoms and who had an angiographic follow-up at 3 months were included in the study. The extent of CAD was calculated using the Gensini score.Results: The incidence of ISR observed in our group of patients was 23.4% (n=87). The mean Gensini score was significantly higher in patients with ISR when compared with group without restenosis (69 [range: 51–90] vs 42 [range: 32–61]; p

Özet

Amaç: Stent içi restenoz (SİR) ile koroner aterosklerozu arasında altta yatan patofizyolojik mekanizmalar açısından önemli farklılıklar vardır. Çalışmamızda ST yükselmeli miyokart enfarktüsünde (STYME) koroner arter hastalığı (KAH) yaygınlığı ile SİR arasındaki ilişkinin değerlendirilmesini ve SİR ile ilişkili olabilecek diğer faktörleri tespit etmeyi amaçladık.Yöntemler: Çalışmamıza ilk kez STYME ile başvuran, ilk 12 saatte primer perkütan koroner girişim ile başarılı bir şekilde tedavi edilen ve üçüncü ayda kontrol anjiyografisi yapılan 372 hasta dahil edildi. KAH yaygınlığı Gensini skoru ile tespit edildi.Bulgular: Çalışmamızda SİR oranı %23.4 (87 hasta) olarak tespit edildi. Ortalama Gensini skoru SİR olan grupta belirgin derecede yüksek bulundu (69 [dağılım, 51-90] ve 42 [dağılım, 32-61], p

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Cite This Article

İYİSOY, A., ÇELİK, M., YÜKSEL, U. Ç., BARÇIN, C., GÖKOĞLAN, Y., YAŞAR, S., GÖRMEL, S., KOKLU, M., YILDIRIM, E., BUĞAN, B. (2022). Primer perkütan koroner girişim ile tedavi edilen ST yükselmeli miyokart enfarktüslü hastalarda stent restenozu ile koroner arter hastalığının yaygınlığı arasındaki ilişkinin değerlendirilmesi. Türk Kardiyoloji Derneği Arşivi, Cilt: 45 - Sayı: 8, 702–714. https://ajindex.com/articles/632288

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