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Journals / Türk Kardiyoloji Derneği Arşivi / 2018 / Cilt: 46 - Sayı: 1

Atherogenic index of plasma as a cardiovascular risk marker in manic, depressive, and euthymic stages of bipolar disorder

Bipolar bozukluğun manik, depresif ve ötimik evrelerinde bir kardiyovasküler risk belirleyicisi olarak aterojenik plazma indeksi

Özge Yüksel
Nesrin Karamustafalıoğlu
Tevfik Kalelioğlu
Mustafa Akkuş
Pelin Ünalan
Burcu Kök
Şule Sözen
Refik Cihnioğlu
Pages
32–38
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The significance level was setat p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Individuals with bipolar disorder (BD) frequentlysuffer from cardiovascular disease (CVD), and it is a leadingcause of mortality.
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Key Findings & Data:Clinicians use routine laboratory tests, including a lipid profile, to predict cardiovascular risk.
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Conclusion & Impact:The significance level was setat p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Individuals with bipolar disorder (BD) frequentlysuffer from cardiovascular disease (CVD), and it is a leadingcause of mortality. Clinicians use routine laboratory tests, including a lipid profile, to predict cardiovascular risk. In addition,a particular lipid ratio, the atherogenic index of plasma (AIP),is a sensitive, new parameter that can be used to assess highrisk groups. To our knowledge, this is the first study evaluatingcardiovascular risk via AIP in different stages of BD.Methods: The study group consisted of male patients withBD who were in a manic, depressive, or euthymic state, andage- and gender-matched healthy controls. Lipid profiles wereanalyzed and the AIP parameter of logarithm of triglyceride(TG) / high-density lipoprotein cholesterol (HDLc) was calculated for all of the participants. The significance level was setat p

Özet

Amaç: Bipolar bozukluğu (BB) olan bireylerde, mortalitenin başlıca nedeni olan kardiyovasküler hastalıklar sıkça görülmektedir. Klinikçiler kardiyovasküler riski öngörmek için lipit profili de dahil olmak üzere rutin laboratuvar testlerini kullanmaktadırlar. Rutin testlerin yanında, lipit parametrelerinin çeşitli oranlamalarıyla hesaplanan aterojenik plazma indeksi (APİ) de, yüksek riskli grupları değerlendirmek için kullanılan yeni ve hassas bir parametredir. Bildiğimiz kadarıyla çalışmamız bipolar bozukluğun farklı evrelerinde APİ yoluyla kardiyovasküler riski değerlendiren ilk çalışmadır. Yöntemler: Çalışmamızın grupları, BB tanılı ve manik, depresif veya ötimik dönemde olan hastalar ile yaş-cinsiyet eşleştirilmiş sağlıklı kontrollerden oluşmaktadır. Tüm katılımcılar için lipit profili incelendi ve APİ log (TG / HDLc) parametresi hesaplandı. Anlamlılık düzeyi p

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Cite This Article

Yüksel, Ö., Karamustafalıoğlu, N., Kalelioğlu, T., Akkuş, M., Ünalan, P., Kök, B., Sözen, Ş., Cihnioğlu, R. (2022). Atherogenic index of plasma as a cardiovascular risk marker in manic, depressive, and euthymic stages of bipolar disorder. Türk Kardiyoloji Derneği Arşivi, Cilt: 46 - Sayı: 1, 32–38. https://ajindex.com/articles/632125

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