Journals / Türk Kardiyoloji Derneği Arşivi / 2019 / Cilt: 47 - Sayı: 8

Mitral annular calcification-related calcified amorphous tumor in a patient with normal renal function: a case report

Böbrek fonksiyonu normal olan hastada mitral anüler kalsifikasyonla ilişkili kalsifiye amorf tümör: Bir olgu sunumu

Pages
695–697
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The rare incidence of this tumor in patients with normal renal function highlights the importance of further research of the pathology of this uncommon condition.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:A calcified amorphous tumor (CAT) of the heart is a non-neoplastic mass, characterized by nodules of calcium on a background of amorphous fibrinous material.
📊
Key Findings & Data:An asymptomatic 43-year-old man with normal renal function underwent echocardiography.
💡
Conclusion & Impact:The rare incidence of this tumor in patients with normal renal function highlights the importance of further research of the pathology of this uncommon condition.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

A calcified amorphous tumor (CAT) of the heart is a non-neoplastic mass, characterized by nodules of calcium on a background of amorphous fibrinous material. Mitral annular calcification (MAC) is one of the conditions most frequently associated with CAT. Most MAC-related CAT cases are reported in end-stage renal disease (ESRD) patients. This report is a description of a patient with normal renal function who was incidentally diagnosed with a CAT arising from MAC. An asymptomatic 43-year-old man with normal renal function underwent echocardiography. The echocardiography results revealed a highly mobile hyperechoic mass attached to the atrial side of the mitral annulus superimposed on a heavily calcified mitral annulus. Cardiac surgery and histopathological evaluation confirmed a diagnosis of MAC-related CAT. While MAC-related CAT is usually associated with ESRD patients, the precise etiology and management strategy of this benign tumor remain unclear. The rare incidence of this tumor in patients with normal renal function highlights the importance of further research of the pathology of this uncommon condition.

Özet

Kalbin kalsifiye amorf tümörü (KAT) neoplazik olmayan bir kitle olup amorf fibrinli materiyal üstünde kalsiyum nodülleri ile karakterizedir. Mitral anüler kalsifikasyon (MAK) en büyük sıklıkla KAT ile ilişkili durumlardan biridir. MAK ile ilişkili KAT olgularının çoğu son dönem böbrek hastalarında (SDBH) bildirilmiştir. Bu olgu raporu rastlantısal olarak MAK’dan kaynaklanan KAT tanısı alan böbrek fonksiyonu normal bir hastayı tanımlamaktadır. Böbrek fonksiyonu normal 43 yaşında semptomsuz bir erkek hastaya ekokardiyografi uygulandı. Ekokardiyografi sonuçları çok mobil, mitral kapağın atriyal yüzüne yapışık, son derece kalsifiye mitral kapağı örten hiperekoik bir kitleyi ortaya çıkardı. Kalp cerrahisi ve histopatolojik değerlendirme MAK ile ilişkili KAT tanısını doğruladı. MAK ile ilişkili KAT genellikle SDBH olanlarla ilişkilendirilmesine rağmen bu iyi huylu tümörün kesin etiyoloji ve sağaltım stratejisi hâlâ net değildir. Böbrek fonksiyonları normal hastalarda bu tümörün seyrek görülmesi bu olağandışı durumun patolojisini daha fazla araştırmanın önemini vurgulamaktadır

🔖

Cite This Article

Alizadehasl, A., Mombeini, H., Hosseini, S., Sanati, H. R. (2022). Mitral annular calcification-related calcified amorphous tumor in a patient with normal renal function: a case report. Türk Kardiyoloji Derneği Arşivi, Cilt: 47 - Sayı: 8, 695–697. https://ajindex.com/articles/632103

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (10)

  1. de Hemptinne Q, de Cannière D, Vandenbossche JL, Unger P. Cardiac calcified amorphous tumor: A systematic review of the literature. Int J Cardiol Heart Vasc 2015;7:1–5
  2. Nakamaru R, Oe H, Iwakura K, Masai T, Fujii K. Calcified amorphous tumor of the heart with mitral annular calcification: a case report. J Med Case Rep 2017;11:195
  3. Nishigawa K, Takiuchi H, Kubo Y, Masaki H, Tanemoto K. Calcified amorphous tumor: three-dimensional transesophageal echocardiography. Asian Cardiovasc Thorac Ann 2012;20:355
  4. Matsukuma S, Eishi K, Tanigawa K, Miura T, Matsumaru I, Hisatomi K, et al. Swinging Calcified Amorphous Tumors With Related Mitral Annular Calcification. Ann Thorac Surg 2016;101:e103–5
  5. Kubota H, Fujioka Y, Yoshino H, Koji H, Yoshihara K, Tonari K, et al. Cardiac swinging calcified amorphous tumors in endstage renal failure patients. Ann Thorac Surg 2010;90:1692–4
  6. Kawata T, Konishi H, Amano A, Daida H. Wavering calcified amorphous tumour of the heart in a haemodialysis patient. Interact Cardiovasc Thorac Surg 2013;16:219–20
  7. Fujiwara M, Watanabe H, Iino T, Kobukai Y, Ishibashi K, Yamamoto H, et al. Two cases of calcified amorphous tumor mimicking mitral valve vegetation. Circulation 2012;125:e432–4
  8. Katsuki S, Ito K, Tadokoro T, Sasaguri T, Hisahara M, Mohri M. Mitral annulus calcification-related calcified amorphous tumour trapped and extended by closing aortic valve. Eur Heart J Cardiovasc Imaging 2016;17:585
  9. Thanassoulis G, Campbell CY, Owens DS, Smith JG, Smith AV, Peloso GM, et al; CHARGE Extracoronary Calcium Working Group. Genetic associations with valvular calcification and aortic stenosis. N Engl J Med 2013;368:503–12
  10. Sadeghpour A, Alizadehasl A, Nojoomizadeh L, Pouraliakbar H, Bayati P. A Mitral Annular Calcification-Related Calcified Amorphous Tumor in End-Stage Renal Disease. CASE (Phila) 2017;1:96–8.