Journals / Türk Kardiyoloji Derneği Arşivi / 2019 / Cilt: 47 - Sayı: 6

Prediction of the development of pulmonary arterial hypertension with Tei Index in congenital heart diseases with left-to-right shunt

Soldan sağa şantlı doğumsal kalp hastalıklarında pulmoner arteriyel hipertansiyon gelişiminin Tei indeksi ile öngörülmesi

Pages
466–475
Publication Date
2022-11-05
DOI
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A significant correlation was detected between the Tei Index value measured from the left ventricular posterior wall and the mean PAP (correlation coefficient: 0.491).Conclusion: The right ventricular Tei Index values in chil- dren with CHD and a left-to-right shunt can be used as a pa- rameter to follow up on the potential development of PAH, to make a diagnosis in the early period, and to make a timely decision about surgery.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The aim of this study was to determine the use- fulness of the Tei Index, an echocardiographic parameter, in the early determination of pulmonary artery pressure (PAP) in congenital heart disease (CHD) with a left-to-right shunt.Methods: Right and left ventricular functions were evalu- ated using Tei Index values determined with tissue Doppler echocardiography.
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Key Findings & Data:The presence of pulmonary arterial hyperten- sion (PAH) was defined as a mean PAP of ≥25 mm Hg and a pulmonary vascular resistance index of >3 WU/m2.
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Conclusion & Impact:A significant correlation was detected between the Tei Index value measured from the left ventricular posterior wall and the mean PAP (correlation coefficient: 0.491).Conclusion: The right ventricular Tei Index values in chil- dren with CHD and a left-to-right shunt can be used as a pa- rameter to follow up on the potential development of PAH, to make a diagnosis in the early period, and to make a timely decision about surgery.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: The aim of this study was to determine the use- fulness of the Tei Index, an echocardiographic parameter, in the early determination of pulmonary artery pressure (PAP) in congenital heart disease (CHD) with a left-to-right shunt.Methods: Right and left ventricular functions were evalu- ated using Tei Index values determined with tissue Doppler echocardiography. Cardiac catheterization was performed in all cases. The presence of pulmonary arterial hyperten- sion (PAH) was defined as a mean PAP of ≥25 mm Hg and a pulmonary vascular resistance index of >3 WU/m2. Patients with a pulmonary/systemic blood flow ratio of ≥2 were con- sidered candidates for surgery.Results: The Tei Index values measured from the left ven- tricular posterior wall and the right ventricular anterior wall were found to be significantly higher in the patients with PAH (0.68±0.18, 0.67±0.16, respectively) compared with the patients without PAH (0.56±0.16, p=0.027; 0.51±0.12 p=0.001). A significant correlation was detected between the Tei Index value measured from the left ventricular posterior wall and the mean PAP (correlation coefficient: 0.491).Conclusion: The right ventricular Tei Index values in chil- dren with CHD and a left-to-right shunt can be used as a pa- rameter to follow up on the potential development of PAH, to make a diagnosis in the early period, and to make a timely decision about surgery.

Özet

Amaç: Çalışmamızın amacı, soldan sağa şantlı doğumsal kalp hastalıklarında pulmoner arter basıncını belirlemede bir ekokardiyografik parametre olan Tei İndeksi’nin kullanı- labilirliğinin belirlenmesidir. Yöntemler: İzole soldan sağa şantlı doğumsal kalp hasta- lığı olan ve cerrahi öncesi tanı amaçlı kalp kateterizasyonu yapılan 30 olgu ile 30 sağlıklı çocuk çalışmaya alındı. Grup- ların sağ ve sol ventrikül fonksiyonları Tei İndeksi belirlemek amacıyla doku Doppler ekokardiyografi ile değerlendirildi. Pulmoner ve sistemik kan akımları hesaplandı. Ortalama pulmoner arter basıncı ≥25 mm Hg ve pulmoner vasküler rezistans indeksi >3 WU/m2 olan olgular pulmoner arteriyel hipertansiyon olarak kabul edildi. Pulmoner/sistemik kan akımı oranı ≥2 olanlar cerrahiye uygun olgular olarak de- ğerlendirildi. Bulgular: Sol ventrikül arka duvar ve sağ ventrikül ön du- vardan ölçülen Tei İndeksi değerleri pulmoner arteriyel hi- pertansiyonu olan olgularda (0.68±0.18, 0.67±0.16) pulmo- ner arteriyel hipertansiyonu olmayan olgulara (0.56±0.16, 0.51±0.12) göre belirgin olarak yüksek tespit edildi (p=0.027, p=0.001). Ayrıca, sol ventrikül arka duvardan elde edilen Tei İndeksi ile ortalama pulmoner arter basıncı arasında belirgin korelasyon olduğu görüldü (korelasyon katsayısı: 0.491). Sonuç: Soldan sağa şantlı doğumsal kalp hastalığı bulunan çocuklarda özellikle sağ ventrikülün çeşitli bölgelerinden öl- çülen Tei İndeksi değerleri, pulmoner arteriyel hipertansiyon gelişiminin takibinde, bunun erken tanısında ve uygun za- manda cerrahiye karar vermede kullanılabilir.

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Cite This Article

ALP, H., BAYSAL, T., YORULMAZ, A., KARAARSLAN, S., YÜCEL, M. (2022). Prediction of the development of pulmonary arterial hypertension with Tei Index in congenital heart diseases with left-to-right shunt. Türk Kardiyoloji Derneği Arşivi, Cilt: 47 - Sayı: 6, 466–475. https://ajindex.com/articles/632081

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