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Journals / Türk Kardiyoloji Derneği Arşivi / 2019 / Cilt: 47 - Sayı: 7

The effect of hemodialysis adequacy on ventricular repolarization in end-stage kidney disease

Son dönem böbrek hastalarında hemodiyaliz etkinliğinin ventriküler repolarizasyon üzerine etkisi

Fürüzan KÖKTÜRK
Bülent KAYA
Saime PAYDAŞ
Ülkü ADAM
Engin ONAN
Belma KALAYCI
Süleyman KALAYCI
Serkan BESLİ
Pages
572–580
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

After an HD session, heart rate increased, blood pressure decreased, and the QT, QTc,QT maximum, QTd, Tp-e interval, and Tp-e/QT were prolonged (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Ventricular repolarization (VR) markers may predict ventricular arrhythmias and cardiac arrest.
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Key Findings & Data:The aim of this study was to investigate the acute effects of a hemodialysis (HD) session and HD adequacy on VR markers in HDpatients.Methods: This cross-sectional study was conducted at 2 university hospitals with 83 patients and VR markers were measured before and after an HD session: QT, QTc, QT minimum, QT maximum, dispersion of QT (QTd), T-peak to T-end (Tp-e) interval, and Tp-e/QT.
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Conclusion & Impact:After an HD session, heart rate increased, blood pressure decreased, and the QT, QTc,QT maximum, QTd, Tp-e interval, and Tp-e/QT were prolonged (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Ventricular repolarization (VR) markers may predict ventricular arrhythmias and cardiac arrest. The aim of this study was to investigate the acute effects of a hemodialysis (HD) session and HD adequacy on VR markers in HDpatients.Methods: This cross-sectional study was conducted at 2 university hospitals with 83 patients and VR markers were measured before and after an HD session: QT, QTc, QT minimum, QT maximum, dispersion of QT (QTd), T-peak to T-end (Tp-e) interval, and Tp-e/QT. Kt/V measurements calculated using the second generation Daugirdas formula were used to indicate dialysis adequacy. The patients were divided into 2 groups according to the Kt/V value. Group 1 patients had a Kt/V of ≤1.6 with a standard dialysis dose, and Group 2 comprised those with a measurement of >1.6 with a high dialysis dose.Results: There were 36 patients in Group 1 and 47 patients in Group 2. There were statistically significantly more female patients in Group 2 (p=0.016). After an HD session, heart rate increased, blood pressure decreased, and the QT, QTc,QT maximum, QTd, Tp-e interval, and Tp-e/QT were prolonged (p

Özet

Amaç: Ventriküler repolarizasyon belirteçleri ventriküler aritmileri ve kardiyak arresti öngörebilir. Bu çalışma hemodiyaliz hastalarında hemodiyaliz seansının ve hemodiyaliz etkinliğinin akut etkilerinin ventiküler repolarizasyon üzerine etkisini araştırmayı amaçlamıştır.Yöntemler: İki üniversite hastanesinde gerçekleştirilen çalışma kesitsel olarak düzenlendi, 83 hemodiyaliz hastasında ventriküler repolarizasyon belirteçleri hemodiyaliz seansının öncesinde ve sonrasında ölçüldü. Bunlar: QT, QTc, QT minimum, QT maksimum, QT dispersionu (QTd), Tp-e intervali ve Tp-e/QT. İkinci jenerasyon Daugirdas formülü ile hesaplanan Kt/V diyaliz etkinliğini yansıtır. Hastalar Kt/V değerine göre grup 1 ≤1.6 standart diyaliz dozu olarak ve grup 2 >1.6 yüksek diyaliz doz alarak ikiye ayrıldı.Bulgular: Otuz altı hasta grup 1’de ve 47 hasta grup 2’deydi. Kadın hastalar istatistiksel açıdan anlamlı olarak grup 2’de daha fazlaydı (p=0.016). Hemodiyaliz sonrası kalp hızı arttı ve kan basıncı azaldı, QT, QTc, QT maksimum, QTd, Tpe intervali ve Tpe/QT ise hemodiyaliz seansı sonrasında uzuyordu (p

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Cite This Article

KÖKTÜRK, F., KAYA, B., PAYDAŞ, S., ADAM, Ü., ONAN, E., KALAYCI, B., KALAYCI, S., BESLİ, S. (2022). The effect of hemodialysis adequacy on ventricular repolarization in end-stage kidney disease. Türk Kardiyoloji Derneği Arşivi, Cilt: 47 - Sayı: 7, 572–580. https://ajindex.com/articles/632054

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