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Journals / Türk Kardiyoloji Derneği Arşivi / 2020 / Cilt: 48 - Sayı: 1

Implications of continuous positive airway pressure on heart rate variability in patients with obstructive sleep apnea: Does gender matter?

Obstrüktif uyku apneli hastalarda sürekli pozitif havayolu basıncı tedavisinin kalp hızı değişkenliği üzerine etkisi: Cinsiyetin önemi nedir?

Murat BİTEKER
Oğuzhan ÇELİK
Ali Rıza BİLGE
Volkan DOĞAN
Özcan BAŞARAN
Bülent ÖZLEK
Eda ÖZLEK
Cem ÇİL
Pages
26–35
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

After 1 year of CPAP treatment, heart rate decreased (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective:This study was designed to determine the ef-fectiveness of continuous positive airway pressure (CPAP) treatment on the improvement of heart rate variability (HRV) and whether gender plays a role in HRV in patients with mode-rate to severe obstructive sleep apnea syndrome (OSAS).Methods:Consecutive patients with recently diagnosed moderate to severe OSAS underwent continuous synchro-nized electrocardiographic monitoring and were prospec-tively considered for inclusion in the study.
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Key Findings & Data:HRV was ana-lyzed before starting CPAP therapy and 1 year thereafter.
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Conclusion & Impact:After 1 year of CPAP treatment, heart rate decreased (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective:This study was designed to determine the ef-fectiveness of continuous positive airway pressure (CPAP) treatment on the improvement of heart rate variability (HRV) and whether gender plays a role in HRV in patients with mode-rate to severe obstructive sleep apnea syndrome (OSAS).Methods:Consecutive patients with recently diagnosed moderate to severe OSAS underwent continuous synchro-nized electrocardiographic monitoring and were prospec-tively considered for inclusion in the study. HRV was ana-lyzed before starting CPAP therapy and 1 year thereafter. The effects of CPAP on HRV were evaluated in men and women separately to ascertain whether there are gender dif-ferences in the clinical manifestations of OSAS and whether female HRV responses to CPAP are similar to those of men.Results:A total of 18 patients (10 men, median age: 56 years) were included in the study. There were no signifi-cant differences in the baseline clinical characteristics of the male and female patients. After 1 year of CPAP treatment, heart rate decreased (p

Özet

Amaç:Bu çalışmada, orta ve ciddi obstrüktif uyku apne sendromlu (OUAS) hastalarda sürekli pozitif hava yolu ba-sıncı (SPHB) tedavisinin kalp hızı değişkenliğini (KHD) iyi-leştirmedeki etkinliğini ve bu etkinlikte cinsiyetin rol oynayıp oynamadığını araştırmayı amaçladık. Yöntemler:Orta ve ciddi OUAS tanısı olan ve dışlama kri-terleri dışında kalan ardışık hastalar çalışmaya ileriye yö-nelik olarak dahil edilerek, sürekli senkronize elektrokardi-yografik inceleme yapıldı. SPHB tedavisine başlanmadan önce ve tedavi başlangıcından bir yıl sonraki sürede KHD analizi yapıldı. SPHB’nin, KHD üzerine olan etkilerinde cin-siyet farklılığı olup olmadığını incelemek ve SPHB yanıtının kadın ve erkeklerde farklı olup olmadığını analiz etmek için erkek ve kadınlarda ayrı ayrı değerlendirme yapıldı. Bulgular:Çalışmaya 18 hasta (10 erkek, ortanca yaş 56) dahil edildi. Erkek ve kadın hastalar arasında bazal klinik özellikler açısından anlamlı farklılık yoktu. Bir yıllık SPHB tedavisi sonrasında hem erkek hem kadınlarda; ortalama kalp hızının azaldığı (p

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Cite This Article

BİTEKER, M., ÇELİK, O., BİLGE, A. R., DOĞAN, V., BAŞARAN, Ö., ÖZLEK, B., ÖZLEK, E., ÇİL, C. (2022). Implications of continuous positive airway pressure on heart rate variability in patients with obstructive sleep apnea: Does gender matter?. Türk Kardiyoloji Derneği Arşivi, Cilt: 48 - Sayı: 1, 26–35. https://ajindex.com/articles/631981

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References (14)

  1. Eckert DJ, Malhotra A. Pathophysiology of Adult Obstructive Sleep Apnea. Proc Am Thorac Soc 2008;5:144−53
  2. Yaggi HK, Concato J, Kernan WN, Lichtman JH, Brass LM, Mohsenin V. Obstructive sleep apnea as a risk factor for stroke and death. N Engl J Med 2005;353:2034−41
  3. Sorajja D, Gami AS, Somers VK, Behrenbeck TR, GarciaTouchard A, Lopez-Jimenez F. Independent association between obstructive sleep apnea and subclinical coronary artery disease. Chest 2008;133:927−33
  4. Jean-Louis G, Zizi F, Clark LT, Brown CD, McFarlane SI. Obstructive sleep apnea and Cardiovascular Disease: Role of the Metabolic Syndrome and Its Components. J Clin Sleep Med 2008;4:261−72
  5. Guilleminault C, Poyares D, Rosa A, Huang YS. Heart rate variability, sympathetic and vagal balance and EEG arousals in upper airway resistance and mild obstructive sleep apnea syndromes. Sleep Med 2005;6:451−7
  6. Smith RP, Veale D, Pépin JL, Lévy PA. Obstructive sleep apnoea and the autonomic nervous system. Sleep Med Rev 1998;2:69−92
  7. Aydin M, Altin R, Ozeren A, Kart L, Bilge M, Unalacak M. Cardiac autonomic activity in obstructive sleep apnea: timedependent and spectral analysis of heart rate variability using 24-hour Holter electrocardiograms. Tex Heart Inst J 2004;31:132−6
  8. Urbanik D, Gać P, Martynowicz H, Poręba M, Podgórski M, Negrusz-Kawecka M, et al. Obstructive sleep apnea as a predictor of reduced heart rate variability. Sleep Med 2018;54:8−15
  9. Spicuzza L, Caruso D, Di Maria G. Obstructive sleep apnea syndrome and its management. Ther Adv Chronic Dis 2015;6:273−85
  10. Romero-Corral A, Somers VK, Pellikka PA, Olson EJ, Bailey KR, Korinek J, et al. Decreased Right and Left Ventricular Myocardial Performance in Obstructive Sleep Apnea. Chest 2007;132:1863−70
  11. Dursunoglu N, Dursunoglu D, Ozkurt S, Gür S, Ozalp G, Evyapan F. Effects of CPAP on right ventricular myocardial performance index in obstructive sleep apnea patients without hypertension. Respir Res 2006;7:22
  12. Stein PK, Bosner MS, Kleiger RE, Conger BM. Heart rate variability: a measure of cardiac autonomic tone. Am Heart J 1994;127:1376−81
  13. Véber O, Lendvai Z, Ronai KZ, Dunai A, Zoller R, Lindner AV, et al. Obstructive sleep apnea and heart rate variability in male patients with metabolic syndrome: cross-sectional study. Metab Syndr Relat Disord 2014;12:117−24
  14. Weaver TE, Grunstein RR. Adherence to continuous positive airway pressure therapy: the challenge to effective treatment. Proc Am Thorac Soc 2008