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Journals / Türk Kardiyoloji Derneği Arşivi / 2020 / Cilt: 48 - Sayı: 1

The relationship between a combination of vitamin D deficiency and hyperuricemia and the severity of coronary artery disease in myocardial infarction patients

Miyokart enfarktüslü hastalarda D vitamini eksikliği ve hiperürisemi birlikteliğinin koroner arter hastalığı ciddiyeti ile ilişkisi

Mustafa Umut SOMUNCU
Ferit AKGÜL
Mustafa Ozan ÇAKIR
Murat CAN
Nail Güven SERBEST
Tunahan AKGÜN
Fatih Paşa TATAR
Abdulkadir TEKİN
Pages
10–19
Publication Date
2022-11-06
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

A 2x2 factorial design was used to create groups according to the presence of hyperuricemia(>7 mg/dL) and vitamin D deficiency (

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Vitamin D deficiency has been shown to be associated with coronary artery disease (CAD).
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Key Findings & Data:In addition, there are studies suggesting that hyperuricemia is an independent risk factor for atherosclerosis, whereas the relationship between the combination of these 2 parameters and severity of CAD remains unclear.
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Conclusion & Impact:A 2x2 factorial design was used to create groups according to the presence of hyperuricemia(>7 mg/dL) and vitamin D deficiency (
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Vitamin D deficiency has been shown to be associated with coronary artery disease (CAD). In addition, there are studies suggesting that hyperuricemia is an independent risk factor for atherosclerosis, whereas the relationship between the combination of these 2 parameters and severity of CAD remains unclear. The aim of this study was to investigate the association between the combination of vitamin D deficiencyand hyperuricemia and the extent of CAD.Methods: A total of 502 patients who had experienced myocardial infarction (MI) were included in this cross-sectional study. The 25-hydroxyvitamin D (25OHD) and serumuric acid (SUA) levels were measured in blood samples taken at the time of admission. A 2x2 factorial design was used to create groups according to the presence of hyperuricemia(>7 mg/dL) and vitamin D deficiency (

Özet

Amaç: Vitamin D eksikliğinin koroner arter hastalığıyla ilişkisi gösterilmiştir. Ayrıca, hiperüriseminin de aterosklerozun bağımsız prediktörü olduğuna dair çalışmalar mevcuttur. Bununla birlikte, bu iki parametrenin birlikteliğinin koroner arter hastalığının ciddiyeti ile ilişkisi net değildir. Çalışmamızda, Vitamin D eksikliği ve hiperürisemi varlığının koroner arter hastalığının ciddiyeti ile ilişkisi olup olmadığını araştırmayı amaçladık. Yöntemler: Bu kesitsel çalışmaya miyokart enfarktüs tanılı 502 hasta alındı. 25-hidroksivitamin D (25OHD) ve serum ürik asit (SUA) seviyesi hastane başvurusu sırasında alınan kandan ölçüldü. Hiperürisemi (>7 mg/dL) ve vitamin D eksikliği (

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Cite This Article

SOMUNCU, M. U., AKGÜL, F., ÇAKIR, M. O., CAN, M., SERBEST, N. G., AKGÜN, T., TATAR, F. P., TEKİN, A. (2022). The relationship between a combination of vitamin D deficiency and hyperuricemia and the severity of coronary artery disease in myocardial infarction patients. Türk Kardiyoloji Derneği Arşivi, Cilt: 48 - Sayı: 1, 10–19. https://ajindex.com/articles/631952

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