Journals / Türk Kardiyoloji Derneği Arşivi / 2020 / Cilt: 48 - Sayı: 1

Admission Tpe interval predicts reperfusion success in STEMI patients treated with fibrinolytic agents

Başvuru anındaki Tpe aralığı fibrinolitik ajan ile tedavi edilen STYME hastalarında reperfüzyon başarısını öngörür

Pages
49–57
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

The average Tpe interval on the admission ECG was shorter (91.7 vs. 100.9 milliseconds [ms]) (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Myocardial infarction is a leading cause of morbidity and mortality.
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Key Findings & Data:Fibrinolytic administration is still a lifesaving choice in ST-segment elevated myocardial infarction(STEMI), but the rate of successful reperfusion can be inconsistent.
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Conclusion & Impact:The average Tpe interval on the admission ECG was shorter (91.7 vs. 100.9 milliseconds [ms]) (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Myocardial infarction is a leading cause of morbidity and mortality. Fibrinolytic administration is still a lifesaving choice in ST-segment elevated myocardial infarction(STEMI), but the rate of successful reperfusion can be inconsistent. Failed reperfusion adds additional clinical risks to rescue percutaneous coronary intervention for STEMIpatients. The interval between the peak of the T wave and the end of the T wave (Tpe) and the ratio of Tpe and a corrected measurement of the time from the start of the Q waveto the end of the T wave (Tpe/QTc ratio) are relatively new electrocardiogram (ECG) indices and have not yet been tested in STEMI patients treated with fibrinolytic agents.Methods: A total of 177 STEMI patients (mean age: 60.5±11.1 years; 138 men and 39 women) were enrolled in this retrospective study to evaluate ECG parameters.The Tpe interval and the Tpe/QTc ratio at baseline and at the 90th minute following the administration of fibrinolytic therapy were analyzed. The clinical and ECG findings ofsuccessful and failed reperfusion groups were compared.Results: Successful reperfusion was achieved in 119 patients (67.2%). The average Tpe interval on the admission ECG was shorter (91.7 vs. 100.9 milliseconds [ms]) (p

Özet

Amaç: Miyokart enfarktüsü günümüzde morbidite ve mortalitenin en sık rastlanan sebebidir. Fibrinolitik uygulanması ST-segment yükselmeli miyokart enfarktüsünde (STYME) hayat kurtarıcı bir seçenek olmaya devam etmektedir, öte yandan başarılı reperfüzyon oranları net değildir. Başarısız reperfüzyon takiben uygulanacak kurtarıcı perkütan koroner girişim (PKG) esnasında STYME hastaları için ek klinik risk durumu oluşturmaktadır. Tpe aralığı ve Tpe/QTc oranı yeni tanımlanan elektrokardiyografi (EKG) parametreleridir ve fibrinolitik ajanlar ile tedavi edilen STYME hastalarında daha önce araştırılmamıştır. Yöntemler: Çalışmaya 177 STYME hastası (ortalama yaş 60.5±11.1 yıl: 138 erkek ve 39 kadın) dahil edildi ve EKG parametreleri geriye dönük olarak incelendi. Tpe aralığı ve Tpe/QTc oranı başvuru anı ve fibrinolitik uygulanmasını takiben 90. dakikada ölçüldü. Klinik özellikler ve EKG bulguları başarılı ve başarısız reperfüzyon gruplarında karşılaştırıldı. Bulgular: Başarılı reperfüzyon 119 hastada izlendi (%67.2). Başvuru anındaki ortalama Tpe aralığı başarılı reperfüzyon sağlananlarda daha kısa idi (91.7 ve 100.9 ms) (p

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Cite This Article

AKKÜÇÜK, M. H., ALTIN, C., AKINCI, S., ÇONER, A., MÜDERRİSOĞLU, H. (2022). Admission Tpe interval predicts reperfusion success in STEMI patients treated with fibrinolytic agents. Türk Kardiyoloji Derneği Arşivi, Cilt: 48 - Sayı: 1, 49–57. https://ajindex.com/articles/631926

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