Journals / Türk Jinekoloji ve Obstetrik Derneği Dergisi / 2014 / Cilt: 11 - Sayı: 4

Endometrium kanserinde preoperatif ultrasonografik endometrial kalınlık ölçümü ile evre ve derece tahmini

Prediction of tumor grade and stage in endometrial carcinoma by preoperative assessment of sonographic endometrial thickness: Is it possible?

Pages
211–214
Publication Date
2022-11-05
DOI
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J Turk Soc Obstet Gynecol 2014;4:211-4

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Objective & Hypothesis:Objective: To evaluate preopertive accuracy of endometrial thickness for assesment of histologic grade and stage of endometrial carcinoma and also determining a cut-off value for the determination of grade of endometrial carcinoma.
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Key Findings & Data:Materials and Methods: Clinical data of 105 patients who underwent surgical staging with endometrial carcinoma were reviewed retrospectively.
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Conclusion & Impact:J Turk Soc Obstet Gynecol 2014;4:211-4
🔬Design:Review & Systematic Survey
📍Scope:2014 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: To evaluate preopertive accuracy of endometrial thickness for assesment of histologic grade and stage of endometrial carcinoma and also determining a cut-off value for the determination of grade of endometrial carcinoma. Materials and Methods: Clinical data of 105 patients who underwent surgical staging with endometrial carcinoma were reviewed retrospectively. Preoperatively endometrial thickness were recorded and correlated with pathologic information. Results: A statistically significant correlation was found in between endometrial thickness and grade of the disease (r=0.746, p=0.001). Besides, no correlation was found between endometrial thickness and stage (r=0.153, p=0.119). The endometrial thickness at 9 mm revealed the optimal sensitivity and specificity (93.33 and 26.2, respectively) for turning through grade1 to grade 2 with 68.2% positive predictive value and 66.7% negative predictive value. We indicated the endometrial thickness at 27 mm as the optimal value with sensitivity and specificity (27.27 and 95.65, respectively) for turning through grade 2 to grade 3 with 66.7% positive predictive value and 77.5% negative predictive value. Conclusion: In conlusion, sonographic evaluation of the endometrial thickness is economical, simple and can be used as a prognostic tool for endometrial cancer grading. The operating team may have the chance to get prepared before the operation and may have the chance to inform the patient about the operation. J Turk Soc Obstet Gynecol 2014;4:211-4

Özet

Amaç: Endometrial karsinomda histolojik derece ve evrenin değerlendirilmesinde endometrial kalınlığın preoperatif doğruluğunu değerlendirmek ve aynı zamanda endometrial karsinom derecesinin belirlenmesinde bir kestirim değeri belirlemek. Gereç ve Yöntemler: Endometrial karsinom nedeniyle cerrahi evreleme yapılmış 105 hastaya ait klinik veriler retrospektif olarak incelenmiştir. Preoperatif endometrial kalınlık kayıt edilmiş ve patolojik sonuç ile korele edilmiştir. Bulgular: Endometrial kalınlık ve hastalığın derecesi arasında istatistiksel anlamlı korelasyon saptanmıştır (r=0,746, p=0,001). Bunun yanı sıra, endometrial kalınlık ve evre arasında hiçbir korelasyon belirlenmemiştir (r=0,153, p=0,119). Grade 1den grade 2ye geçişte %68,2 pozitif prediktif değer ve %66,7 negatif prediktif değer ile 9 mmlik endometrial kalınlık en optimal duyarlılık ve özgüllüğe sahiptir (sırasıyla 93,33 ve 26,2). Grade 2den grade 3e geçişte %66,7 pozitif prediktif değer ve %77,5 negatif prediktif değer ile 27 mmlik endometrial kalınlığın en optimal duyarlılık ve özgüllüğe sahip olduğunu belirledik (sırasıyla 27,27 ve 95,65). Sonuç: Endometrial kalınlığın sonografik değerlendirilmesi ekonomik ve basittir ve endometrial kanser gradelendirilmesinde prognostik bir araç olarak kullanılabilir. Operasyon ekibi operasyondan önce hazırlık yapma ve hastayı operasyon hakkında bilgilendirme şansına sahip olabilir. J Turk Soc Obstet Gynecol 2014;4:211-4

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Cite This Article

ÇORAKÇI, A., YÜCESOY, İ., ÖZCAN, C., ÇAKIROĞLU, Y., NALBANT, B., YILDIRIM, Ş. K., DOĞER, E. (2022). Endometrium kanserinde preoperatif ultrasonografik endometrial kalınlık ölçümü ile evre ve derece tahmini. Türk Jinekoloji ve Obstetrik Derneği Dergisi, Cilt: 11 - Sayı: 4, 211–214. https://ajindex.com/articles/631454

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