Journals / Türkiye Tıp Dergisi Dahili Tıp Bilimleri / 1999 / Cilt: 6 - Sayı: 2

Pre- ve postmenopozal kadınlarda serum osteokalsin ve tip 1 prokollajen düzeyleri

Serum levels of osteocalcin and type 1 procollagen in pre- and postmenopausal women

Pages
102–104
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

As a result, we may conclude that serum osteocalcin and type-1 procollagen levels, biochemical markers of bone formation, are increased in postmenopausal women.

📌 3 Key Takeaways

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Objective & Hypothesis:This study was performed to obtain information about bone formation in postmenopausal period by determining serum osteocalcin and type-1 procollagĞn levels in both pre-ând postmenopausal women and to compare them with bone mineral density (BMD).
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Key Findings & Data:Study group comprised 46postmenopausal and 35premenopausal wo¬men.
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Conclusion & Impact:As a result, we may conclude that serum osteocalcin and type-1 procollagen levels, biochemical markers of bone formation, are increased in postmenopausal women.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

This study was performed to obtain information about bone formation in postmenopausal period by determining serum osteocalcin and type-1 procollagĞn levels in both pre-ând postmenopausal women and to compare them with bone mineral density (BMD). Study group comprised 46postmenopausal and 35premenopausal wo¬men. In the postmenopausal women, we found that the levels of serum osteocalcin and type-1 procollagen were, 22.4±9- 74 ng/ml and 101.0+44.1 ng/ml, respectively, and BMD was 611.7±193- 7gr/ cm?. The same values in premenopausal women were as follows; 1735±4.9 ng/ml for serum osteocalcin, 94.4±24.7 ng/ml for type-1 procollagen, and 927.7±171.4 gr/cm? for BMD. As a result, we may conclude that serum osteocalcin and type-1 procollagen levels, biochemical markers of bone formation, are increased in postmenopausal women.

Özet

Bu çalişma preve postmenopozal kadınlarda serum osteokalsin ve tip-1 prokollajen miktarlarını tayin ederek, kemik mineral yoğunluğu (KMY) ile karşılaştırmak ve postmenopozal dönemde oluşan kemik formasyonu hakkında bilgi edinmek amacıyla yapılmıştır. Çalışmaya 46'sıpostmenopozal 35'ipremenopozal olmak üzere toplam 81 kadın olgu dahil edilmiştir. Postmenopozal kadınlarda serum osteokalsin düzeyi 22.4+9- 7 ng/ml, tip-1 prokollajen düzeyi 101.0+44.1 ng/ml ve KMY ise 611.7±193- 7 gr/cm3 olarak bulundu. Aynı değerler premenopozal kadınlarda, sırasıyla, 1735+4.9 ng/ml, 94.4+24.7 ng/ml ve 927.7+171.4 gr/cm olarak tespit edildi. Sonuç olarak, postmenopozal dönemde kemik oluşumunun biyokimyasal belirteçleri olan serum osteokalsin ve tip-1 prokollajen miktarları artmış, buna karşılık KMY azalmış olup aralarında ters bir ilşki mevcuttur.

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Cite This Article

TARÇIN, O., ÇAKIR, B., BAYKAL, Y., YÖNEM, A., KOCABALKAN, F. (2022). Pre- ve postmenopozal kadınlarda serum osteokalsin ve tip 1 prokollajen düzeyleri. Türkiye Tıp Dergisi Dahili Tıp Bilimleri, Cilt: 6 - Sayı: 2, 102–104. https://ajindex.com/articles/631375