Journals / Türkiye Tıp Dergisi Dahili Tıp Bilimleri / 2000 / Cilt: 7 - Sayı: 3

İdiopatik trombositopenik purpuralı çocuklarda human parvovirüs B19 seroprevalansı

Human parvovirus B19 seroprevalence in children with idiopathic thrombocytopenic purpura

Pages
128–131
Publication Date
2022-11-04
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Our findings in patients with ITP provides support for the hypothesis that HPV-B19 may be a role forHPV-B19 infection with HPV-B19-associated ITP.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The association between idiopathic thrombocytopenic purpura (ITP) and certain viral diseases in childhood has been well established.
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Key Findings & Data:However, the role of Human Parvovirus B19 (HPV-B19) in ITP has yet to be defined.
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Conclusion & Impact:Conclusion: Our findings in patients with ITP provides support for the hypothesis that HPV-B19 may be a role forHPV-B19 infection with HPV-B19-associated ITP.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: The association between idiopathic thrombocytopenic purpura (ITP) and certain viral diseases in childhood has been well established. However, the role of Human Parvovirus B19 (HPV-B19) in ITP has yet to be defined. We herein compare the results of parvovirus HPV-B19 antibody response in 19 patients with ITP in comparison with the antibody response in healthy children. Method: In this study, we analyzed patients with ITP and 29 normal controls in order to determine the prevalence of HPV-B19 IgM and IgG antibodies using enzyme-linked immunosorbent assay (ELISA). Results: We found that HPV-B19 IgM was positive in 5 of 19 patients with ITP, whereas it was positive in 1 of 29 children in the control group. Conclusion: Our findings in patients with ITP provides support for the hypothesis that HPV-B19 may be a role forHPV-B19 infection with HPV-B19-associated ITP.

Özet

Amaç: İdiopatik trombositopenik purpura (ÎTP) ile bazı çocukluk çağı viral hastalıklarının birlikteliği iyi bir şekilde tanımlanmıştır. Bununla birlikte Human parvovirus B19'un (HPV-B19) iTP'deki rolü henüz tam olarak aydınlatılamamıştır. Biz burada sağlıklı çocuklarla iTP'li 19 hastadaki HPV-B19 antikor yanıtlarını kıyasladık. Yöntem: Bu çalışmada "enzyme-linked immunosorbent assay" (ELISA) yöntemini kullanarak HPV-B19 IgM ve IgG antikorlarının varlığını saptamak için ITP'H 19 hasta ve 29 sağlıklı bireyi analiz ettik. Bulgular: iTP'li hastadan 5'inde ve kontrol grubunda 29 hastadan 1'inde HPV-B19 IgM'i pozitif olarak bulduk. Yorum: ITP'H hastalardaki bulgularımız, HPV-B19 enfeksiyonu ile İTP'nin ilişkili olabileceği yönündeki hipotezleri destekler niteliktedir.

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Cite This Article

ÖZKAYA, E., ALTAY, Ç., GÜVENER, E., ÖZBEK, N., AKTEPE, O. (2022). İdiopatik trombositopenik purpuralı çocuklarda human parvovirüs B19 seroprevalansı. Türkiye Tıp Dergisi Dahili Tıp Bilimleri, Cilt: 7 - Sayı: 3, 128–131. https://ajindex.com/articles/631335