Journals / Türkiye Parazitoloji Dergisi / 2004 / Cilt: 28 - Sayı: 3

Sudan'da yetişen bazı bitkilerle (neem, garad, sarmısak) kutanöz leishmaniasisin tedavisi

Treatment of cutaneous leishmaniasis with some local sudanese plants (Neem, Garad and Garlic)

Pages
129–132
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Leishmanol and garad (Acacia nilotica) showed significant difference from the control (P= 0.05 & 0.04 respectively).

📌 3 Key Takeaways

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Objective & Hypothesis:A total of 72 cutaneous leishmaniasis (CL) cases referred to the Wad Madani Teaching Hospital between September 1999 and December 2000 were included in the present study.
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Key Findings & Data:The duration of lesions varied between several days and more than one year, with the duration of most of them ranging between 1-3 months (91.6%).
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Conclusion & Impact:Leishmanol and garad (Acacia nilotica) showed significant difference from the control (P= 0.05 & 0.04 respectively).
🔬Design:Research Article
📍Scope:2000 Verileri
⚙️Variables:Domain Parameters

Abstract

A total of 72 cutaneous leishmaniasis (CL) cases referred to the Wad Madani Teaching Hospital between September 1999 and December 2000 were included in the present study. The patients were from different parts of the Gezira State. The duration of lesions varied between several days and more than one year, with the duration of most of them ranging between 1-3 months (91.6%). Different types of lesions were observed such as ulcerative (63.9%), nodular (31.9%), nodular/ulcerative (2.8%), and fungal/ulcerative (1.4%). These lesions were found on different parts of the body including the limbs (87.5%), face (1.4%), and trunk (1.4%). The number of lesions varied between 1 and 16. The CL cases were treated using medicinal agents and plant methanol extracts. All agents showed goodresponse (90.3%). The response ratio of medicinal agents to plant methanol extracts was 1.03:1. Garlic (Allium sativa) showed 100% response, with no significant difference from pentostam (p= 0.75). Also neem {Azadirachta indica) showed an insignificant difference from pentostam (P= 0.09). Leishmanol and garad (Acacia nilotica) showed significant difference from the control (P= 0.05 & 0.04 respectively).

Özet

Bu çalışmaya, Eylül 1999 ile Aralık 2000 tarihleri arasinda Wad Madani Eğitim Hastanesi'ne başvuran ve Gezira Eyaleti'nin farklı bölgelerinden gelen 72 kutanöz leishmaniasisli (KL) hasta dahil edilmiştir. Hastalardaki lezyonların süresinin birkaç gün ile bir yıldan fazla, çoğunun -3 ay arasında (%91.6) olduğu saptanmıştır. Lezyonların, ülseratif (%63.9), nodular (%31.9), nodular/ülseratif (%2.8) ve mantar enfeksiyonlu/ülseratif (%1.4) gibi farklı tiplerde olduğu ve %87.5'inin kol ve bacaklarda, %1.4'ünün yüzde ve %1.4'ünün gövdede bulunduğu görülmüştür. Lezyon sayısının 1 ile 16 arasinda değiştiği belirlenmiştir. Bu hastalar, konvansiyonel ilaçlar ve bitki etanol ekstratları kullanılarak tedavi edilmiş ve bütün ajanlarla %90.3 civarında olumlu sonuç alınarak, tedavide iyi oldukları görülmüştür.Konvansiyonel ajanlarla, bitki etanol ekstratlarına verilen cevap arasındaki oranın 1.03:1 olduğu saptanmıştır. Allium sativa (sarımsak) %100 olumlu sonuç verirken, pentostam ile arasında anlamlı bir fark olmadığı bulunmuştur (p=0.75). Azadirachta indica (Neem) da aynı şekilde yüksek etkili bulunmuş, ve pentostam ile anlamlı fark saptanmamıştır (p=0.09). Leishmanol (p=0.05) ve Acacia nilotica (garad) (p=0.04) ise kontrol ile önemli derecede farklılık göstermiştir.

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Cite This Article

KHALID, F. A., MOHOMED, H. E. O., TOUM, A. M., MAGZOUB, M. M. A., ALI, M. S., ABDALLA, N. M. (2022). Sudan'da yetişen bazı bitkilerle (neem, garad, sarmısak) kutanöz leishmaniasisin tedavisi. Türkiye Parazitoloji Dergisi, Cilt: 28 - Sayı: 3, 129–132. https://ajindex.com/articles/630904

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