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Journals / Türkiye Parazitoloji Dergisi / 2005 / Cilt: 29 - Sayı: 1

Sudan'da yetişen bazı bitkilerin anti-kutanöz leishmaniasis aktivitesinin in vitro olarak değerlendirilmesi

In vitro assessment of anti-cutaneous leishmaniasis activity of some Sudanese plants

Fatima A. KHALID
Husam Eldin O. MOHOMED
Abdalla M. TOUM
Mubark M. A. MAGZOUB
M. Siddig ALİ
Nazar M. ABDALLA
Pages
3–6
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Extracts of Balanites aegyptiaca had a moderate biological activity on L major promastigotes.

📌 3 Key Takeaways

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Objective & Hypothesis:Examination of crude methanol extracts of four Sudanese plants (Azadirachta indica, Acacia nilotica, Balanites aegyptiaca and Allium sativa) revealed that only three species had a considerable in-vitro anti-leishmanial activity on Leishmania major promastigotes.
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Key Findings & Data:The plants Azadrachta indica, Allium sativa, and Acacia nilotica gave a LC50 of 10.2, 4.94, and 89.38 μg/ml, respectively.
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Conclusion & Impact:Extracts of Balanites aegyptiaca had a moderate biological activity on L major promastigotes.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Examination of crude methanol extracts of four Sudanese plants (Azadirachta indica, Acacia nilotica, Balanites aegyptiaca and Allium sativa) revealed that only three species had a considerable in-vitro anti-leishmanial activity on Leishmania major promastigotes. The plants Azadrachta indica, Allium sativa, and Acacia nilotica gave a LC50 of 10.2, 4.94, and 89.38 μg/ml, respectively. Extracts of Balanites aegyptiaca had a moderate biological activity on L major promastigotes.

Özet

Sudan'da yetişen dört bitkinin (Azadirachta indica, Acacia nilotica, Balanites aegyptiaca and Allium sativa) ham metanol ekstraktlarinin incelenmesi sonucunda, sadece üç tanesinin Leishmania major promastigotlarına karşı in vitro olarak etkisi olduğu görülmüştür. Azadrachta indica, Allium sativa, and Acacia nilotica bitkilerinin ekstraklari için %50 öldürücü konsantrasyonun (LCSO) sırasıyla 10.2, 4.94, 89.38 ug/mL olduğu, Balanites aegyptiaca ekstrakti ise L major promastigotlari üzerine orta derecede etkiye sahip olduğu saptanmıştır.

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Cite This Article

KHALID, F. A., MOHOMED, H. E. O., TOUM, A. M., MAGZOUB, M. M. A., ALİ, M. S., ABDALLA, N. M. (2022). Sudan'da yetişen bazı bitkilerin anti-kutanöz leishmaniasis aktivitesinin in vitro olarak değerlendirilmesi. Türkiye Parazitoloji Dergisi, Cilt: 29 - Sayı: 1, 3–6. https://ajindex.com/articles/630877

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